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The map label for this gene is corA [H]

Identifier: 68537110

GI number: 68537110

Start: 2351849

End: 2352892

Strand: Direct

Name: corA [H]

Synonym: jk2015

Alternate gene names: 68537110

Gene position: 2351849-2352892 (Clockwise)

Preceding gene: 68537103

Following gene: 68537112

Centisome position: 95.51

GC content: 56.42

Gene sequence:

>1044_bases
ATGGCAAAGCACGAACCAAACCGGATCCGGGTCCCCGTCGAACGAGCTATCCGCGAGTGTCGCCTTTATGTACAGGGCAA
GCAGTACCCAGGTCAGGCCAACTACATCACGGCTCTCAAGGACATCGAGGAGCTGTCGGATGGCACCAGTCAGGACTTTG
TCATGGTGACCCTGGAGGAGCCCTCCGAGGAACAGATGTTGCGTGTCGCCCAGCGCTATGGCGTCGACGAACTGATTGTT
GAAGATGCCGTCAATGCCCACCAGCGTGCAAAGGTGGAGCGCTACGAGGATCAGCTGTTTTCTGTCATCCGCTCCGTCCA
ATATGCGGATAACCAGGACATCATCGACCGGCGCGACATCATTCAAACCGGCGAAGTGCAGATGGTCATTGGCCGGAAGT
TCATCATCGTCATTTCCCACGGCACGGATCTCCCAAACCCTGAGATGCGGCTCCACCAGGCCCCGGAGCTACGCAGCAAA
GGGCCGCTCTCTATTGCGTGGGCTATCTCGGATTATCTAGTCGACGAGTACACACGCATCGCCGAACAGCTCGAAACCCG
GGTCGATGATCTCGAAGAGGAGGTCTTCACCCTCCGCGACGAGTTCGACATCGAGAACATCTACACCCTCAAGCGCGAGA
TCTTGGAAATGCGGCATGCTATCGACCCACTGATCCCCGCCCTGCGCGCGTTGATCCAAAATCATAAGGATCTCACGTCC
AAGCAGATTCGGGCCTTCTTCCGCGATGTGCTGGATCACGCCATGTTGGCAAAGGACAAGATCGATTCCTTCGACGAGCG
ACTGTCGTCCCTTATCCAGGCGGGTTCGGCGATCATTTCCTTGCGTCAAAACCAAGATATGCGCACGATTTCCGCGGTCG
TCGGTATGGCCGCCGCCCCGACAATGATTGCGGGTGTGTACGGCATGAACTTCGAAAACATGCCTGAGCTGCAGTGGCAC
TACGCGTACTACGTCTGCTTAGCGGCGATGGTTGGCGTAGTCGCGTTGATGTGGTGGTGGTTTAAACACAACAACTGGCT
ATAG

Upstream 100 bases:

>100_bases
CAGTGCTACGGGCTGACGGTTAGGATATCGACAGGCTGCGAGGGACAAGCAGCGGTGCAGCACCGCGCGAACCACCGGGT
TTAGTTGGAAAGGACTCACC

Downstream 100 bases:

>100_bases
CCCAGCTCCCGAGCCCCAAGTCCCGTCCCCCGGTAATAGATAAAAAAGGGGACCCCGCGCACCCGTCAGAGCTCGTTGAC
CCTTGCTGCATTCCTGCCCT

Product: putative magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAKHEPNRIRVPVERAIRECRLYVQGKQYPGQANYITALKDIEELSDGTSQDFVMVTLEEPSEEQMLRVAQRYGVDELIV
EDAVNAHQRAKVERYEDQLFSVIRSVQYADNQDIIDRRDIIQTGEVQMVIGRKFIIVISHGTDLPNPEMRLHQAPELRSK
GPLSIAWAISDYLVDEYTRIAEQLETRVDDLEEEVFTLRDEFDIENIYTLKREILEMRHAIDPLIPALRALIQNHKDLTS
KQIRAFFRDVLDHAMLAKDKIDSFDERLSSLIQAGSAIISLRQNQDMRTISAVVGMAAAPTMIAGVYGMNFENMPELQWH
YAYYVCLAAMVGVVALMWWWFKHNNWL

Sequences:

>Translated_347_residues
MAKHEPNRIRVPVERAIRECRLYVQGKQYPGQANYITALKDIEELSDGTSQDFVMVTLEEPSEEQMLRVAQRYGVDELIV
EDAVNAHQRAKVERYEDQLFSVIRSVQYADNQDIIDRRDIIQTGEVQMVIGRKFIIVISHGTDLPNPEMRLHQAPELRSK
GPLSIAWAISDYLVDEYTRIAEQLETRVDDLEEEVFTLRDEFDIENIYTLKREILEMRHAIDPLIPALRALIQNHKDLTS
KQIRAFFRDVLDHAMLAKDKIDSFDERLSSLIQAGSAIISLRQNQDMRTISAVVGMAAAPTMIAGVYGMNFENMPELQWH
YAYYVCLAAMVGVVALMWWWFKHNNWL
>Mature_346_residues
AKHEPNRIRVPVERAIRECRLYVQGKQYPGQANYITALKDIEELSDGTSQDFVMVTLEEPSEEQMLRVAQRYGVDELIVE
DAVNAHQRAKVERYEDQLFSVIRSVQYADNQDIIDRRDIIQTGEVQMVIGRKFIIVISHGTDLPNPEMRLHQAPELRSKG
PLSIAWAISDYLVDEYTRIAEQLETRVDDLEEEVFTLRDEFDIENIYTLKREILEMRHAIDPLIPALRALIQNHKDLTSK
QIRAFFRDVLDHAMLAKDKIDSFDERLSSLIQAGSAIISLRQNQDMRTISAVVGMAAAPTMIAGVYGMNFENMPELQWHY
AYYVCLAAMVGVVALMWWWFKHNNWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=107, Percent_Identity=32.7102803738318, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40172; Mature: 40040

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHEPNRIRVPVERAIRECRLYVQGKQYPGQANYITALKDIEELSDGTSQDFVMVTLEE
CCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECC
PSEEQMLRVAQRYGVDELIVEDAVNAHQRAKVERYEDQLFSVIRSVQYADNQDIIDRRDI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IQTGEVQMVIGRKFIIVISHGTDLPNPEMRLHQAPELRSKGPLSIAWAISDYLVDEYTRI
HCCCCEEEEECCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
AEQLETRVDDLEEEVFTLRDEFDIENIYTLKREILEMRHAIDPLIPALRALIQNHKDLTS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQIRAFFRDVLDHAMLAKDKIDSFDERLSSLIQAGSAIISLRQNQDMRTISAVVGMAAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TMIAGVYGMNFENMPELQWHYAYYVCLAAMVGVVALMWWWFKHNNWL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKHEPNRIRVPVERAIRECRLYVQGKQYPGQANYITALKDIEELSDGTSQDFVMVTLEE
CCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECC
PSEEQMLRVAQRYGVDELIVEDAVNAHQRAKVERYEDQLFSVIRSVQYADNQDIIDRRDI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IQTGEVQMVIGRKFIIVISHGTDLPNPEMRLHQAPELRSKGPLSIAWAISDYLVDEYTRI
HCCCCEEEEECCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
AEQLETRVDDLEEEVFTLRDEFDIENIYTLKREILEMRHAIDPLIPALRALIQNHKDLTS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQIRAFFRDVLDHAMLAKDKIDSFDERLSSLIQAGSAIISLRQNQDMRTISAVVGMAAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TMIAGVYGMNFENMPELQWHYAYYVCLAAMVGVVALMWWWFKHNNWL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]