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The map label for this gene is yprA [H]

Identifier: 68537050

GI number: 68537050

Start: 2283522

End: 2285876

Strand: Direct

Name: yprA [H]

Synonym: jk1956

Alternate gene names: 68537050

Gene position: 2283522-2285876 (Clockwise)

Preceding gene: 68537046

Following gene: 68537051

Centisome position: 92.73

GC content: 67.56

Gene sequence:

>2355_bases
ATGTCCGACTCCACGCCCCCTACCCCAGCCTCCACGCCCGGCGGCACGGCACCGTCTTTCGGCGAGGAACTTCTGGCCGA
TCTGACGCCCGAATTTCCGCGCTCCACCGTCACCCATACACACACCATTCCCGCCCGCCCATCGCAGACGGCGCAGTGGC
CAGAATGGGCCGATGAGACTCTGGTGGAATACCTGCATGAACAGGGAATTTCCACACCGTGGTCGCACCAGGTGGAGACC
GCGAACCACGCACACGCGGGGCGGGATGTGGTGGTCGCCACCGGCACGGCGTCCGGAAAGAGCCTCGGCTACCAGCTAGC
GGCCTTGAGCGACCTGGCTACGGCGAGCACCTCGACGGCCCTTTATATTGCACCGACGAAGGCCCTGGCGCAGGACCAGC
GGGCGGCGCTGGCGCGAATGTGCGCGGGCGCGGTGAACCTGAACGACATCATGGTGGCCACCTACGACGGCGACACTCCA
CCCGAGACGCGGCGGGTGATCCGCGACCAGGCGCGGGTGATCGTGACGAACCCGGACATGTTGCATGCCTCGATCCTGGG
GAATCCGCAGTCGTGGAGCCGACTGCTGCGCACGCTGCGCTACGTGGTGATCGACGAATGCCACGTATATCGCGGGGTGT
TCGGCGCGCACGTAGCGATGGTGCTGCGCAGGCTTCTGCGGCTGTGTGGGACGGCCCCGACGATCGTGCTCGCATCCGCG
ACCAGCGTGGATCCGGCGGCGCACGCACGCCGACTGACGGGGCGGTCAGACGTGGTGGCGGTGACGCAGGACGGGGCGCC
CGCGGGAGAACGGACCGTCGCGCTGTGGGAGCCCGGATTCCTGCCAGATATGGAAGGCGAAAACGGCGCCCCGGTTCGGC
GGGCGGCGAATTCCGAGGCTGCGGACGTGATGGGGTTGGCAATCGCCCAGGGCGCGCGGACGCTGACTTTCGTGCGCTCC
CGGCGCGGGGCGGAAGTGGTTTCCGTCGCCGCCGCGGAGAAGCTGTCGGCGATGGGGCGCAGCGCGGATGCGGTGCGGGT
GGCGGCCTATCGCGCGGGCTACACCCCGGAGGATCGCCGCGAGCTGGAGCGTCGCTTCGACAATGGCGAACTGCTGGGTA
TTGCCTCGACGAACGCCCTGGAGCTGGGCATCGACGTCGGCGGGCTGGACGTGGTGGTGACTAGCGGCTTCCCCGGCACT
ATCGCGAGCTTCCGGCAGCAGGCGGGCCGCGCGGGCAGGCGCGGACAAGGTGCGCTGGTGGTGCTGGTCGGTGCGGACGA
CCCGATGGATACGTACTTACTGCACCACCCGGAGGCCTTGCTGGATCGGCCGGTAGAGAACACTGTGTTCGATCCGACGA
ACCCCTACGTGCTGGCCGATCATGTGGTGTGTGCGGCGGCGGAGAAGCCCCTTTCTGAGGCGGAGGTTGCGCACTGGGGT
GCGGAGCGGGTGGTGGAACACCTGCTGCGCCAGGGTGCACTGAAGCGCAGGCCGCGAGGCATTTTTGCAGACCTGAAGGT
CGCGGAGCAGGTGCATTCGCAGGTGTCGATTCGTGGCGGTGCGGCAGCCCAGGTGGCGATCGTGGAGGTCGATTCCGGTC
GACTGCTGGGCACGGTGGATCAGTCGCGCGCAACGTCGGACGTGCACACGGGGGCGGTGTACATGCATCAGGGCGAGACG
TTTGTGGTGCAGCTGCTGGACCTGGAGGAGTCCGTGGCGTGGGTGCGGCCGGAGTTCCCGGAGTACACCACCCAGGTGAT
CCGCGATACCGACATTGCGGTACGGCGCACCCGGGGGACGCGCAAGGTCTGCGAGGGGGTGTGGCTGGCGGATGTGGACG
TGGAGGTTTCGCACACCGTCAGCGGTTATCGAAAGCGCCTGCCGGGTGGCGAGATCCTGGAGACCGTGCCGCTGGACGTG
CCGCCGGAATCGCTGCGCACCCGCGCGGTGGCTTACACCGTGGACCCGGATGTGCTGCTGGATCTGGGGTTGCCGGAGCC
GACGTGGCCGGGGACGTTGCATGCCGCGGAACATGCGGCGATTGGACTATTGCCGCTGATTGCGACGTGCGACCGCTGGG
ATATTGGTGGCGTTTCTACCGCTTTACATGCGGATACGGGCCTACCGACGGTGTTTGTGTACGACGGCTATGCAGGCGGC
GCGGGCTTCGCCGAACAGGGCTTTGCGCGCTTTGCCGAGTGGATGGCCGCCACCGCCGAGACCGTGGAGACCTGCGAGTG
CGAGTCCGGCTGCCCGTCTTGTGTGCAGTCGCCGAAGTGCGGCAATGGCAACGATCCGCTGTTCAAGGCGGGTGCGGTGT
TGTTGTTGCAAACGCTGGCCGGGGCGGCGGGTTAG

Upstream 100 bases:

>100_bases
CGACAGTCTGCCACGTTGCGGGTTAAACATTCAGACGAGCTTGGATTCTGCAGGACAATAACTTGTATCCACCCCCTAAT
GGGGTCTAGAACTAACGTTA

Downstream 100 bases:

>100_bases
TTCACTGTTTTTCTTTGGGACGCCCACATCGCAGCTTGCCCGAGAATATACTTTCCCCCATGAAGGCTTTTTCTGGGAAT
AATCACACTGGGTTCCGGCG

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MSDSTPPTPASTPGGTAPSFGEELLADLTPEFPRSTVTHTHTIPARPSQTAQWPEWADETLVEYLHEQGISTPWSHQVET
ANHAHAGRDVVVATGTASGKSLGYQLAALSDLATASTSTALYIAPTKALAQDQRAALARMCAGAVNLNDIMVATYDGDTP
PETRRVIRDQARVIVTNPDMLHASILGNPQSWSRLLRTLRYVVIDECHVYRGVFGAHVAMVLRRLLRLCGTAPTIVLASA
TSVDPAAHARRLTGRSDVVAVTQDGAPAGERTVALWEPGFLPDMEGENGAPVRRAANSEAADVMGLAIAQGARTLTFVRS
RRGAEVVSVAAAEKLSAMGRSADAVRVAAYRAGYTPEDRRELERRFDNGELLGIASTNALELGIDVGGLDVVVTSGFPGT
IASFRQQAGRAGRRGQGALVVLVGADDPMDTYLLHHPEALLDRPVENTVFDPTNPYVLADHVVCAAAEKPLSEAEVAHWG
AERVVEHLLRQGALKRRPRGIFADLKVAEQVHSQVSIRGGAAAQVAIVEVDSGRLLGTVDQSRATSDVHTGAVYMHQGET
FVVQLLDLEESVAWVRPEFPEYTTQVIRDTDIAVRRTRGTRKVCEGVWLADVDVEVSHTVSGYRKRLPGGEILETVPLDV
PPESLRTRAVAYTVDPDVLLDLGLPEPTWPGTLHAAEHAAIGLLPLIATCDRWDIGGVSTALHADTGLPTVFVYDGYAGG
AGFAEQGFARFAEWMAATAETVETCECESGCPSCVQSPKCGNGNDPLFKAGAVLLLQTLAGAAG

Sequences:

>Translated_784_residues
MSDSTPPTPASTPGGTAPSFGEELLADLTPEFPRSTVTHTHTIPARPSQTAQWPEWADETLVEYLHEQGISTPWSHQVET
ANHAHAGRDVVVATGTASGKSLGYQLAALSDLATASTSTALYIAPTKALAQDQRAALARMCAGAVNLNDIMVATYDGDTP
PETRRVIRDQARVIVTNPDMLHASILGNPQSWSRLLRTLRYVVIDECHVYRGVFGAHVAMVLRRLLRLCGTAPTIVLASA
TSVDPAAHARRLTGRSDVVAVTQDGAPAGERTVALWEPGFLPDMEGENGAPVRRAANSEAADVMGLAIAQGARTLTFVRS
RRGAEVVSVAAAEKLSAMGRSADAVRVAAYRAGYTPEDRRELERRFDNGELLGIASTNALELGIDVGGLDVVVTSGFPGT
IASFRQQAGRAGRRGQGALVVLVGADDPMDTYLLHHPEALLDRPVENTVFDPTNPYVLADHVVCAAAEKPLSEAEVAHWG
AERVVEHLLRQGALKRRPRGIFADLKVAEQVHSQVSIRGGAAAQVAIVEVDSGRLLGTVDQSRATSDVHTGAVYMHQGET
FVVQLLDLEESVAWVRPEFPEYTTQVIRDTDIAVRRTRGTRKVCEGVWLADVDVEVSHTVSGYRKRLPGGEILETVPLDV
PPESLRTRAVAYTVDPDVLLDLGLPEPTWPGTLHAAEHAAIGLLPLIATCDRWDIGGVSTALHADTGLPTVFVYDGYAGG
AGFAEQGFARFAEWMAATAETVETCECESGCPSCVQSPKCGNGNDPLFKAGAVLLLQTLAGAAG
>Mature_783_residues
SDSTPPTPASTPGGTAPSFGEELLADLTPEFPRSTVTHTHTIPARPSQTAQWPEWADETLVEYLHEQGISTPWSHQVETA
NHAHAGRDVVVATGTASGKSLGYQLAALSDLATASTSTALYIAPTKALAQDQRAALARMCAGAVNLNDIMVATYDGDTPP
ETRRVIRDQARVIVTNPDMLHASILGNPQSWSRLLRTLRYVVIDECHVYRGVFGAHVAMVLRRLLRLCGTAPTIVLASAT
SVDPAAHARRLTGRSDVVAVTQDGAPAGERTVALWEPGFLPDMEGENGAPVRRAANSEAADVMGLAIAQGARTLTFVRSR
RGAEVVSVAAAEKLSAMGRSADAVRVAAYRAGYTPEDRRELERRFDNGELLGIASTNALELGIDVGGLDVVVTSGFPGTI
ASFRQQAGRAGRRGQGALVVLVGADDPMDTYLLHHPEALLDRPVENTVFDPTNPYVLADHVVCAAAEKPLSEAEVAHWGA
ERVVEHLLRQGALKRRPRGIFADLKVAEQVHSQVSIRGGAAAQVAIVEVDSGRLLGTVDQSRATSDVHTGAVYMHQGETF
VVQLLDLEESVAWVRPEFPEYTTQVIRDTDIAVRRTRGTRKVCEGVWLADVDVEVSHTVSGYRKRLPGGEILETVPLDVP
PESLRTRAVAYTVDPDVLLDLGLPEPTWPGTLHAAEHAAIGLLPLIATCDRWDIGGVSTALHADTGLPTVFVYDGYAGGA
GFAEQGFARFAEWMAATAETVETCECESGCPSCVQSPKCGNGNDPLFKAGAVLLLQTLAGAAG

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=491, Percent_Identity=27.0875763747454, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320497, Length=811, Percent_Identity=32.059186189889, Blast_Score=428, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 83512; Mature: 83381

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSTPPTPASTPGGTAPSFGEELLADLTPEFPRSTVTHTHTIPARPSQTAQWPEWADET
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHH
LVEYLHEQGISTPWSHQVETANHAHAGRDVVVATGTASGKSLGYQLAALSDLATASTSTA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCE
LYIAPTKALAQDQRAALARMCAGAVNLNDIMVATYDGDTPPETRRVIRDQARVIVTNPDM
EEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCE
LHASILGNPQSWSRLLRTLRYVVIDECHVYRGVFGAHVAMVLRRLLRLCGTAPTIVLASA
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TSVDPAAHARRLTGRSDVVAVTQDGAPAGERTVALWEPGFLPDMEGENGAPVRRAANSEA
CCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCH
ADVMGLAIAQGARTLTFVRSRRGAEVVSVAAAEKLSAMGRSADAVRVAAYRAGYTPEDRR
HHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHH
ELERRFDNGELLGIASTNALELGIDVGGLDVVVTSGFPGTIASFRQQAGRAGRRGQGALV
HHHHHCCCCCEEEEECCCEEEEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEE
VLVGADDPMDTYLLHHPEALLDRPVENTVFDPTNPYVLADHVVCAAAEKPLSEAEVAHWG
EEECCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCEEEECCEEEHHCCCCCHHHHHHHCC
AERVVEHLLRQGALKRRPRGIFADLKVAEQVHSQVSIRGGAAAQVAIVEVDSGRLLGTVD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCEEEECC
QSRATSDVHTGAVYMHQGETFVVQLLDLEESVAWVRPEFPEYTTQVIRDTDIAVRRTRGT
HHCCCCCCCCCEEEEECCCEEEEEEECHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCH
RKVCEGVWLADVDVEVSHTVSGYRKRLPGGEILETVPLDVPPESLRTRAVAYTVDPDVLL
HHHHCCCEEEECCEEHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHCEEEEEEECCCEEE
DLGLPEPTWPGTLHAAEHAAIGLLPLIATCDRWDIGGVSTALHADTGLPTVFVYDGYAGG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCCCC
AGFAEQGFARFAEWMAATAETVETCECESGCPSCVQSPKCGNGNDPLFKAGAVLLLQTLA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
GAAG
CCCC
>Mature Secondary Structure 
SDSTPPTPASTPGGTAPSFGEELLADLTPEFPRSTVTHTHTIPARPSQTAQWPEWADET
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHH
LVEYLHEQGISTPWSHQVETANHAHAGRDVVVATGTASGKSLGYQLAALSDLATASTSTA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCE
LYIAPTKALAQDQRAALARMCAGAVNLNDIMVATYDGDTPPETRRVIRDQARVIVTNPDM
EEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEECCCE
LHASILGNPQSWSRLLRTLRYVVIDECHVYRGVFGAHVAMVLRRLLRLCGTAPTIVLASA
EEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
TSVDPAAHARRLTGRSDVVAVTQDGAPAGERTVALWEPGFLPDMEGENGAPVRRAANSEA
CCCCHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHCCCCCH
ADVMGLAIAQGARTLTFVRSRRGAEVVSVAAAEKLSAMGRSADAVRVAAYRAGYTPEDRR
HHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHH
ELERRFDNGELLGIASTNALELGIDVGGLDVVVTSGFPGTIASFRQQAGRAGRRGQGALV
HHHHHCCCCCEEEEECCCEEEEEEEECCEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEE
VLVGADDPMDTYLLHHPEALLDRPVENTVFDPTNPYVLADHVVCAAAEKPLSEAEVAHWG
EEECCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCEEEECCEEEHHCCCCCHHHHHHHCC
AERVVEHLLRQGALKRRPRGIFADLKVAEQVHSQVSIRGGAAAQVAIVEVDSGRLLGTVD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEEEECCCCEEEECC
QSRATSDVHTGAVYMHQGETFVVQLLDLEESVAWVRPEFPEYTTQVIRDTDIAVRRTRGT
HHCCCCCCCCCEEEEECCCEEEEEEECHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCH
RKVCEGVWLADVDVEVSHTVSGYRKRLPGGEILETVPLDVPPESLRTRAVAYTVDPDVLL
HHHHCCCEEEECCEEHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHCEEEEEEECCCEEE
DLGLPEPTWPGTLHAAEHAAIGLLPLIATCDRWDIGGVSTALHADTGLPTVFVYDGYAGG
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCCCC
AGFAEQGFARFAEWMAATAETVETCECESGCPSCVQSPKCGNGNDPLFKAGAVLLLQTLA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
GAAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]