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The map label for this gene is cya

Identifier: 68537046

GI number: 68537046

Start: 2277364

End: 2278896

Strand: Direct

Name: cya

Synonym: jk1952

Alternate gene names: NA

Gene position: 2277364-2278896 (Clockwise)

Preceding gene: 68537044

Following gene: 68537050

Centisome position: 92.48

GC content: 66.34

Gene sequence:

>1533_bases
ATGAAACAACTGCTGCGCTACCTCTCGTGGGCCTGGGGAACCTCCTGGCCCCTGTACGCAGCAACCGTTCTGGCCACGAA
CGTCATCGGCGCGACCGCCGTAGCGACGTTCCTACGCTTCCTCATCCCCCTGCCTGCCGCGCGTGAGCTGACGAGCCCGG
ATACCACCATCGCCTCGCTGTACCTGATCTACTTCGGGGTGGCCGTGGTCGCCGGCATCGCGATGACGTTGTACTTCTTC
GCGCCCGTCCTGCGCTGGCAGCGCACGCCGCAGGCTTATGACCCGAATATGGTGCGCGACTTGGTGCTGCGCATTCCCTT
GCTGCAGACCGTCACAGGCATCGTGCTGTGGGGCATCGGCGTGGTGCTATTCACCGTTGTGGCCTGGAGGCATAGCACCG
AGTGGGGCATAACCGTCGGTGTGACGGCAACGCTCGGCGGCATGATGGTGAGCCTGATGACGTACATGGAGGCCGAGCGC
CTGGTGCGCCCGGTCGCCGCAAAGGCGCTGGCCAAGGGCGCACCAGACCACTCACGGCTCTCTCCGCTGTCGCACCGCCT
GATGACTACGTGGGCGCTGACTTCTGCTGTGCCCGTGTTGGGCATGGTGCTGCTGCTCTTCGCTGCGGCCACTGAGTTCT
ACCCCGAAAGCTCGCGTGGCATCATCCCGGCGATGCTGGCGTTGGCGCTGACTACCCTGCTGACCGGCTTCATGGGCACC
ACACTGTTCTCCATGGCCGTGGCTGACCCGATCCGCGAGCTGCAGTACGCCATCAACCGCGTACGTCGCGGCAAGGTGAA
CACCGACGTGCGGATCTACGATTCCTCGGAGATCGGCGTGCTGCAGGCCGGCTTCAACGAGATGATGCGCGGCCTGCAGG
AACGCCAGCGGGTCTCGGACCTCTTTGGCCGCTACGTCGGCACCGAGGTCGCTCGCCGCGCGCTAGAGGAGAAGCCGGAG
CTGGGCGGCGAAACCCGTCATGTGGCCGTGCTCTTCGTGGACGTGATCGGCTCCACCGGGTTCGCCACGGAGAAGGAACC
GCAGCACGTGGTGAAGGCCCTCAACGAGTTCTTCGACCGCGTGGTGGAGGTCGTACATGCCAACAAGGGCATCATCAACA
AGTTCGAGGGCGATGCCGCGCTGGCCGTGTTCGGCGCGCCTCTGCCGCTGGATGATGTGGCCGGCCACGCCCTGGCCGCC
GCCCGCGAGCTGAAGGCGAAGCTGCAGGGGCTGGAGTTCGCCGCGGGAGTTGGCGTGGCCGCCGGTTCCGTCGTCGCGGG
CCACATCGGCGCGAAGGATCGCTTCGAGTACACCGTCATCGGCGACGCTGTGAACCAGGCCGCCCGTCTGACGGACCTGG
CGAAGAAAACCCCCGGACAGGTGCTGACCAGTGCCGCGACCCTGCGCGCGGCCAACGAGGCCGAGCAAGCTCGCTGGACC
ATGATGAAATCCGTGGAGCTACGCGGCCGCCGCGAGATGACGCAGATCGCCCGCCCCATCCGCGCGACCCTGGCCGACCG
TTCGGAGGCTTAG

Upstream 100 bases:

>100_bases
GTGGTTTCCGTCATGGTTACTCAGTGTAGCTACCGACAAGGATAGACAAGGACAGGGCAGACGCACCCGGCGCGGGGCAG
CGTGCGTTAATCTGAAGGGC

Downstream 100 bases:

>100_bases
GCCCCGCGCCGTACTGCGGCGATGGGGAGGTTTCTTTTCGACGCCACCTCGTCCCACCACGCCGCCGTTTTCCGTCCCAC
TGCCGCGGCCAGCTGCTCTG

Product: adenylate cyclase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKQLLRYLSWAWGTSWPLYAATVLATNVIGATAVATFLRFLIPLPAARELTSPDTTIASLYLIYFGVAVVAGIAMTLYFF
APVLRWQRTPQAYDPNMVRDLVLRIPLLQTVTGIVLWGIGVVLFTVVAWRHSTEWGITVGVTATLGGMMVSLMTYMEAER
LVRPVAAKALAKGAPDHSRLSPLSHRLMTTWALTSAVPVLGMVLLLFAAATEFYPESSRGIIPAMLALALTTLLTGFMGT
TLFSMAVADPIRELQYAINRVRRGKVNTDVRIYDSSEIGVLQAGFNEMMRGLQERQRVSDLFGRYVGTEVARRALEEKPE
LGGETRHVAVLFVDVIGSTGFATEKEPQHVVKALNEFFDRVVEVVHANKGIINKFEGDAALAVFGAPLPLDDVAGHALAA
ARELKAKLQGLEFAAGVGVAAGSVVAGHIGAKDRFEYTVIGDAVNQAARLTDLAKKTPGQVLTSAATLRAANEAEQARWT
MMKSVELRGRREMTQIARPIRATLADRSEA

Sequences:

>Translated_510_residues
MKQLLRYLSWAWGTSWPLYAATVLATNVIGATAVATFLRFLIPLPAARELTSPDTTIASLYLIYFGVAVVAGIAMTLYFF
APVLRWQRTPQAYDPNMVRDLVLRIPLLQTVTGIVLWGIGVVLFTVVAWRHSTEWGITVGVTATLGGMMVSLMTYMEAER
LVRPVAAKALAKGAPDHSRLSPLSHRLMTTWALTSAVPVLGMVLLLFAAATEFYPESSRGIIPAMLALALTTLLTGFMGT
TLFSMAVADPIRELQYAINRVRRGKVNTDVRIYDSSEIGVLQAGFNEMMRGLQERQRVSDLFGRYVGTEVARRALEEKPE
LGGETRHVAVLFVDVIGSTGFATEKEPQHVVKALNEFFDRVVEVVHANKGIINKFEGDAALAVFGAPLPLDDVAGHALAA
ARELKAKLQGLEFAAGVGVAAGSVVAGHIGAKDRFEYTVIGDAVNQAARLTDLAKKTPGQVLTSAATLRAANEAEQARWT
MMKSVELRGRREMTQIARPIRATLADRSEA
>Mature_510_residues
MKQLLRYLSWAWGTSWPLYAATVLATNVIGATAVATFLRFLIPLPAARELTSPDTTIASLYLIYFGVAVVAGIAMTLYFF
APVLRWQRTPQAYDPNMVRDLVLRIPLLQTVTGIVLWGIGVVLFTVVAWRHSTEWGITVGVTATLGGMMVSLMTYMEAER
LVRPVAAKALAKGAPDHSRLSPLSHRLMTTWALTSAVPVLGMVLLLFAAATEFYPESSRGIIPAMLALALTTLLTGFMGT
TLFSMAVADPIRELQYAINRVRRGKVNTDVRIYDSSEIGVLQAGFNEMMRGLQERQRVSDLFGRYVGTEVARRALEEKPE
LGGETRHVAVLFVDVIGSTGFATEKEPQHVVKALNEFFDRVVEVVHANKGIINKFEGDAALAVFGAPLPLDDVAGHALAA
ARELKAKLQGLEFAAGVGVAAGSVVAGHIGAKDRFEYTVIGDAVNQAARLTDLAKKTPGQVLTSAATLRAANEAEQARWT
MMKSVELRGRREMTQIARPIRATLADRSEA

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI24497587, Length=152, Percent_Identity=33.5526315789474, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 55424; Mature: 55424

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]