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The map label for this gene is dtd [H]

Identifier: 68536170

GI number: 68536170

Start: 1285760

End: 1286230

Strand: Direct

Name: dtd [H]

Synonym: jk1093

Alternate gene names: 68536170

Gene position: 1285760-1286230 (Clockwise)

Preceding gene: 68536169

Following gene: 68536171

Centisome position: 52.21

GC content: 58.6

Gene sequence:

>471_bases
ATGAAAGCGGTTGTGAGCACTGTCAGTAGTGCGGAGGTAACCGTAGACGGTGAGGTCGTCGGGTCAGTACAAGGCCCTGC
ATTATTGGCGCTTGTCGGCATCGGTACAGGTGACATAGAAGACGCGAGTGTGACGGACGCGGCTGTGGAGAAGATGGCTC
GGAAGCTCGCCGAATTGCGTCTGCTACCGGCAGTCGGCGAGCCATGGGATAGCCCGCGCAATCATTCAGTCGAGGAGGTC
GGCGGACAAGTCCTGTTGGTCAGCCAGTTCACGCTCATGGGGGAAACGAAGAAAGGGCGGAGGCCCTCCTGGGCGAATGC
GGCGCCGGGTGAGGCTGCACAACCCGTCTTCGACCGTATCAGCGAGCTACTGCGACAGCGCGGAATAGTTGTAGAAACAG
GCCGATTCGGTGCGATGATGAAAGTCTCCAGTGTGAACGAGGGACCATTCACCGTACTGATAGAGACCTAG

Upstream 100 bases:

>100_bases
TTCCGGAAGACTTGCGAGAGCTGTACTAAAGCTCCAGAACTAGAGCCCCAGAAAACCCTATTGTTAGAAATCCCGAGATT
TTGAGGAAGGCGGATCGGCA

Downstream 100 bases:

>100_bases
GTATACCTGCCGTCTTTTGAATAGTTCCAGGTCAAATGCTTGCTTCGCTTTCGCATCGCTAACCGCTGAAACCGGCGACC
CTATTGCGGGGGTAGGGGAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKAVVSTVSSAEVTVDGEVVGSVQGPALLALVGIGTGDIEDASVTDAAVEKMARKLAELRLLPAVGEPWDSPRNHSVEEV
GGQVLLVSQFTLMGETKKGRRPSWANAAPGEAAQPVFDRISELLRQRGIVVETGRFGAMMKVSSVNEGPFTVLIET

Sequences:

>Translated_156_residues
MKAVVSTVSSAEVTVDGEVVGSVQGPALLALVGIGTGDIEDASVTDAAVEKMARKLAELRLLPAVGEPWDSPRNHSVEEV
GGQVLLVSQFTLMGETKKGRRPSWANAAPGEAAQPVFDRISELLRQRGIVVETGRFGAMMKVSSVNEGPFTVLIET
>Mature_156_residues
MKAVVSTVSSAEVTVDGEVVGSVQGPALLALVGIGTGDIEDASVTDAAVEKMARKLAELRLLPAVGEPWDSPRNHSVEEV
GGQVLLVSQFTLMGETKKGRRPSWANAAPGEAAQPVFDRISELLRQRGIVVETGRFGAMMKVSSVNEGPFTVLIET

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=159, Percent_Identity=35.8490566037736, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790320, Length=155, Percent_Identity=37.4193548387097, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533292, Length=159, Percent_Identity=36.4779874213836, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319982, Length=161, Percent_Identity=36.6459627329193, Blast_Score=98, Evalue=5e-22,
Organism=Drosophila melanogaster, GI281361569, Length=158, Percent_Identity=37.3417721518987, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16428; Mature: 16428

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVSTVSSAEVTVDGEVVGSVQGPALLALVGIGTGDIEDASVTDAAVEKMARKLAELR
CCHHHHCCCCCEEEECCEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LLPAVGEPWDSPRNHSVEEVGGQVLLVSQFTLMGETKKGRRPSWANAAPGEAAQPVFDRI
HCCCCCCCCCCCCCCCHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
SELLRQRGIVVETGRFGAMMKVSSVNEGPFTVLIET
HHHHHHCCCEEECCCCCCEEEECCCCCCCEEEEEEC
>Mature Secondary Structure
MKAVVSTVSSAEVTVDGEVVGSVQGPALLALVGIGTGDIEDASVTDAAVEKMARKLAELR
CCHHHHCCCCCEEEECCEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LLPAVGEPWDSPRNHSVEEVGGQVLLVSQFTLMGETKKGRRPSWANAAPGEAAQPVFDRI
HCCCCCCCCCCCCCCCHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHH
SELLRQRGIVVETGRFGAMMKVSSVNEGPFTVLIET
HHHHHHCCCEEECCCCCCEEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA