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The map label for this gene is hrcA

Identifier: 68535672

GI number: 68535672

Start: 727000

End: 728025

Strand: Direct

Name: hrcA

Synonym: jk0600

Alternate gene names: 68535672

Gene position: 727000-728025 (Clockwise)

Preceding gene: 68535671

Following gene: 68535673

Centisome position: 29.52

GC content: 64.33

Gene sequence:

>1026_bases
TTGTCGAGCGGAACGGAACACAGAAGAAACCAAGTGCTGCGGGCGATCGTCAGCGATTTCATCGCCTCGCACGAGCCGGT
GGGCTCGAAGATGCTGGTGGATCGGCACCAGCTGGGCGTTTCCTCCGCGACGATCCGCAACGACATGGCAGTGCTAGAGG
CCGAGGGGTACATCACTCAGCAGCATGCCTCCTCTGGACGCATCCCCACGGTAAAGGGCTACCGCCGCTTCGTGGACGGC
ATTAACGAGGTCAAGCCGCTAAGCACCCCTGAGCGCCGCGCCATCCTGGACTTCCTGGAACATGGCGTGGATCTAGAGGA
TGTTCTGCGCCGCAGCGTGCAGCTGCTTTCCCAGCTGACCCGCCAAGTGGCCGTGGTGCAGATGCCGGACCTGCGGCGCG
GGCGGGTGAAGCACTGCGAGCTGGTGAAGCTGGGCAGCCACCGCATCCTGTTGGTGCTGATCACCGACACGGGGCGCGTG
GATCAGCGCAACGTGGATCTAGGCCAGCCGATCAGTGACGACGATCTGCCGCGGCTGCGCGACCTGGTGAACTCCGCGAT
GGTAGGGCGCACCCTGGACGACGCATGCACCAACATCGCCGCCCTGGCCAACGAGGCCAAGGGCAACAGCATGCCCGAGG
AACTGCGCGACGTCGCACTTGTGGTGACGACCGTGCTGGTGGAGACCCTGCTCGAACGCCCAAACGACCGGCTGATCCTG
GCGGGCACGCCCAACCTGATGCGCACCAGCGAACTCAGCCCCGTGGTGGAAGCACTGGAAGAGCAGGTGGTGGTGCTGAA
GCTGCTGAATAGCGTGCGCGACCTGCAGGTGCAGGTGAGCATCGGCGAGGAGAACGAAGACGAGGAGCTGCGCGGCGCAT
CCGTCGTATCCACCGGCTACGGTAACGCCAACGCGGTGCTCGGCGGAATGGGAGTGGTGGGGCCAACCCACCTGGACTAC
TCCGGCACCATTTCCTCTGTGACCGCCGTGGCGCACTACGTCTCGCGGATTTTGAGCGAAGAGTAG

Upstream 100 bases:

>100_bases
GGCCGACGGGATCGTCACGGACATTGTGTTGGCGCTCGGGCTTTAAGAGCCAATCGAGAGCTAATCGAGGCTGATCGGAC
TCACGCGAGGAGTGAAGGAT

Downstream 100 bases:

>100_bases
GAATAGTAGGATAGTGCAGTTGGTTAAGCACTAAAGACTGCAAGCAACTCAAGATAGACGTGAAAAGGACCCGCTGAACG
TGGCTCGAGACTATTACGGA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSSGTEHRRNQVLRAIVSDFIASHEPVGSKMLVDRHQLGVSSATIRNDMAVLEAEGYITQQHASSGRIPTVKGYRRFVDG
INEVKPLSTPERRAILDFLEHGVDLEDVLRRSVQLLSQLTRQVAVVQMPDLRRGRVKHCELVKLGSHRILLVLITDTGRV
DQRNVDLGQPISDDDLPRLRDLVNSAMVGRTLDDACTNIAALANEAKGNSMPEELRDVALVVTTVLVETLLERPNDRLIL
AGTPNLMRTSELSPVVEALEEQVVVLKLLNSVRDLQVQVSIGEENEDEELRGASVVSTGYGNANAVLGGMGVVGPTHLDY
SGTISSVTAVAHYVSRILSEE

Sequences:

>Translated_341_residues
MSSGTEHRRNQVLRAIVSDFIASHEPVGSKMLVDRHQLGVSSATIRNDMAVLEAEGYITQQHASSGRIPTVKGYRRFVDG
INEVKPLSTPERRAILDFLEHGVDLEDVLRRSVQLLSQLTRQVAVVQMPDLRRGRVKHCELVKLGSHRILLVLITDTGRV
DQRNVDLGQPISDDDLPRLRDLVNSAMVGRTLDDACTNIAALANEAKGNSMPEELRDVALVVTTVLVETLLERPNDRLIL
AGTPNLMRTSELSPVVEALEEQVVVLKLLNSVRDLQVQVSIGEENEDEELRGASVVSTGYGNANAVLGGMGVVGPTHLDY
SGTISSVTAVAHYVSRILSEE
>Mature_340_residues
SSGTEHRRNQVLRAIVSDFIASHEPVGSKMLVDRHQLGVSSATIRNDMAVLEAEGYITQQHASSGRIPTVKGYRRFVDGI
NEVKPLSTPERRAILDFLEHGVDLEDVLRRSVQLLSQLTRQVAVVQMPDLRRGRVKHCELVKLGSHRILLVLITDTGRVD
QRNVDLGQPISDDDLPRLRDLVNSAMVGRTLDDACTNIAALANEAKGNSMPEELRDVALVVTTVLVETLLERPNDRLILA
GTPNLMRTSELSPVVEALEEQVVVLKLLNSVRDLQVQVSIGEENEDEELRGASVVSTGYGNANAVLGGMGVVGPTHLDYS
GTISSVTAVAHYVSRILSEE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_CORJK (Q4JWP8)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250377.1
- HSSP:   Q9WZV5
- STRING:   Q4JWP8
- GeneID:   3433410
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0600
- NMPDR:   fig|306537.3.peg.829
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   CJEI306537:JK0600-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00081
- InterPro:   IPR001034
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 37299; Mature: 37168

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGTEHRRNQVLRAIVSDFIASHEPVGSKMLVDRHQLGVSSATIRNDMAVLEAEGYITQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCHHEEECCCCEEC
QHASSGRIPTVKGYRRFVDGINEVKPLSTPERRAILDFLEHGVDLEDVLRRSVQLLSQLT
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RQVAVVQMPDLRRGRVKHCELVKLGSHRILLVLITDTGRVDQRNVDLGQPISDDDLPRLR
HHHHHHCCCCCCCCCCCHHHEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
DLVNSAMVGRTLDDACTNIAALANEAKGNSMPEELRDVALVVTTVLVETLLERPNDRLIL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AGTPNLMRTSELSPVVEALEEQVVVLKLLNSVRDLQVQVSIGEENEDEELRGASVVSTGY
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHCCCCEEECCC
GNANAVLGGMGVVGPTHLDYSGTISSVTAVAHYVSRILSEE
CCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSGTEHRRNQVLRAIVSDFIASHEPVGSKMLVDRHQLGVSSATIRNDMAVLEAEGYITQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHCHHEEECCCCEEC
QHASSGRIPTVKGYRRFVDGINEVKPLSTPERRAILDFLEHGVDLEDVLRRSVQLLSQLT
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RQVAVVQMPDLRRGRVKHCELVKLGSHRILLVLITDTGRVDQRNVDLGQPISDDDLPRLR
HHHHHHCCCCCCCCCCCHHHEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
DLVNSAMVGRTLDDACTNIAALANEAKGNSMPEELRDVALVVTTVLVETLLERPNDRLIL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
AGTPNLMRTSELSPVVEALEEQVVVLKLLNSVRDLQVQVSIGEENEDEELRGASVVSTGY
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHCCCCEEECCC
GNANAVLGGMGVVGPTHLDYSGTISSVTAVAHYVSRILSEE
CCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA