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The map label for this gene is comEA [H]

Identifier: 68535643

GI number: 68535643

Start: 690665

End: 691549

Strand: Direct

Name: comEA [H]

Synonym: jk0571

Alternate gene names: 68535643

Gene position: 690665-691549 (Clockwise)

Preceding gene: 68535642

Following gene: 68535644

Centisome position: 28.05

GC content: 65.31

Gene sequence:

>885_bases
ATGTCCACACGACGCATGAGGCAGAGTTCTGCTGACAAGGTCCGCGCCCGCGCCGAGGCTTTGGCCCAACCCATGCCGGA
GCATGAACTCGCCAACGTTGACCTAGACACGCATACCGTCATAAGCAGCACTGCGTCCCGGGGGCTTGTCGTCACAGTGG
TCGTGGCAGTTCTCATCAGCGTCGCATTTTTCGCCTGCCAACGGCAGGATTCGGACGACGGGGCAGGCGGCGCCGACATG
CTGGCGACCACGAGCGGACCTGGAGCACCTGGCGGCGCCGCTGATACGGGCATGGGCGGCGCCGTTCCGGCAAGCGATAC
GGGGCAGGCCACAGCCGGGGATGGTAGTCAGTCTGACGAGCAAGCCGAAAGCCAGGAAGTCGTCGTGAGCGTGCAGGGGA
TGGTGCACCATCCGGGGCTGCTCCGGGTGCAGGCCACCACCCGGGTGGGCGAAGCCATAGAGGCCGCAGGCGGAGGTCTT
CCCAAGGCAGTTGTATTGGGCATCAATCTGGCAGAGCCGGTCAGTGATGGAATGCAGATCGTTGTCGATGATCGCGGCTC
GCGCGTGGTGTACGCCGGGGGTGCGCAATCCGCGCCGGGCGGGACCGCAGGAGCGGGCGCGGGCGGGGCGAACCAGGGTG
GTGGGGCAGGCGGTGGTTCTGCGCGTGGGGCGGACGGCGCAAACGGCGCAGACGCCAAGGTGAACCTCAATACCGCTGAC
GCCACGCAGTTGGAAACCATAAGTGGCATCGGTCCTGCCACTGCTGAGGCCATCATCGATTGGAGAGAATCCAACGGTCC
ATTCACCAGCGTTGAGCAGCTCCTGGACGTCCGCGGCATCGGCCCAGCGAAGTTCGAAGCGATGCGCGATGCCGTCACTA
TCTAG

Upstream 100 bases:

>100_bases
TATCCACAGGGGAGGGGTTTTCCACAGCTTCCTGGAGTTTTGACGTTCCAGCTGTGGTATCCGGCGGTCAGTAGTCCGCT
AGACATGTTCTGATCGGCGC

Downstream 100 bases:

>100_bases
CTCCTTTGCGACGGGTCTATGGACGTCCGCGGCACCGCAAGAATCGCCGGAGCCGTTCAGCCCGGAGGCCGTCACCAAAG
CTCGTGGCGTCGATCTGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSTRRMRQSSADKVRARAEALAQPMPEHELANVDLDTHTVISSTASRGLVVTVVVAVLISVAFFACQRQDSDDGAGGADM
LATTSGPGAPGGAADTGMGGAVPASDTGQATAGDGSQSDEQAESQEVVVSVQGMVHHPGLLRVQATTRVGEAIEAAGGGL
PKAVVLGINLAEPVSDGMQIVVDDRGSRVVYAGGAQSAPGGTAGAGAGGANQGGGAGGGSARGADGANGADAKVNLNTAD
ATQLETISGIGPATAEAIIDWRESNGPFTSVEQLLDVRGIGPAKFEAMRDAVTI

Sequences:

>Translated_294_residues
MSTRRMRQSSADKVRARAEALAQPMPEHELANVDLDTHTVISSTASRGLVVTVVVAVLISVAFFACQRQDSDDGAGGADM
LATTSGPGAPGGAADTGMGGAVPASDTGQATAGDGSQSDEQAESQEVVVSVQGMVHHPGLLRVQATTRVGEAIEAAGGGL
PKAVVLGINLAEPVSDGMQIVVDDRGSRVVYAGGAQSAPGGTAGAGAGGANQGGGAGGGSARGADGANGADAKVNLNTAD
ATQLETISGIGPATAEAIIDWRESNGPFTSVEQLLDVRGIGPAKFEAMRDAVTI
>Mature_293_residues
STRRMRQSSADKVRARAEALAQPMPEHELANVDLDTHTVISSTASRGLVVTVVVAVLISVAFFACQRQDSDDGAGGADML
ATTSGPGAPGGAADTGMGGAVPASDTGQATAGDGSQSDEQAESQEVVVSVQGMVHHPGLLRVQATTRVGEAIEAAGGGLP
KAVVLGINLAEPVSDGMQIVVDDRGSRVVYAGGAQSAPGGTAGAGAGGANQGGGAGGGSARGADGANGADAKVNLNTADA
TQLETISGIGPATAEAIIDWRESNGPFTSVEQLLDVRGIGPAKFEAMRDAVTI

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 29054; Mature: 28923

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRRMRQSSADKVRARAEALAQPMPEHELANVDLDTHTVISSTASRGLVVTVVVAVLIS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
VAFFACQRQDSDDGAGGADMLATTSGPGAPGGAADTGMGGAVPASDTGQATAGDGSQSDE
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QAESQEVVVSVQGMVHHPGLLRVQATTRVGEAIEAAGGGLPKAVVLGINLAEPVSDGMQI
HHHHCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEE
VVDDRGSRVVYAGGAQSAPGGTAGAGAGGANQGGGAGGGSARGADGANGADAKVNLNTAD
EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
ATQLETISGIGPATAEAIIDWRESNGPFTSVEQLLDVRGIGPAKFEAMRDAVTI
CHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
STRRMRQSSADKVRARAEALAQPMPEHELANVDLDTHTVISSTASRGLVVTVVVAVLIS
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
VAFFACQRQDSDDGAGGADMLATTSGPGAPGGAADTGMGGAVPASDTGQATAGDGSQSDE
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QAESQEVVVSVQGMVHHPGLLRVQATTRVGEAIEAAGGGLPKAVVLGINLAEPVSDGMQI
HHHHCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEE
VVDDRGSRVVYAGGAQSAPGGTAGAGAGGANQGGGAGGGSARGADGANGADAKVNLNTAD
EEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
ATQLETISGIGPATAEAIIDWRESNGPFTSVEQLLDVRGIGPAKFEAMRDAVTI
CHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]