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The map label for this gene is clpX [H]

Identifier: 68535618

GI number: 68535618

Start: 661836

End: 663110

Strand: Direct

Name: clpX [H]

Synonym: jk0546

Alternate gene names: 68535618

Gene position: 661836-663110 (Clockwise)

Preceding gene: 68535617

Following gene: 68535620

Centisome position: 26.88

GC content: 62.59

Gene sequence:

>1275_bases
ATGCCTGAAAGCGCAGAGCTCCTGAAGTGCTCCTTCTGTGGAAAGAGCCAGAAGCAGGTCCGCAAGCTGATTGCCGGCCC
TGGTGTTTACATTTGCGACGAATGCATCGAGCTTTGTAACGAGATCATCGAAGAGGAGTTGCTGGCGGTCGATCCCGCAG
AGAGCTCGGCGAAGCTGCCGAAGCCCGCGGCCATCGCCGAGTTCCTGGATAGCTACGTGATTGGTCAGGACGAGGCCAAG
CGCACCCTGGCCGTTGCCGTGTACAACCACTACAAGCGCATTCAGGTCGAGGAGTCGAACGCTGCTGCCCGCCGCTCTGA
CGACGAGGTGGAGCTGGCGAAGTCCAACATTCTGATGTTGGGGCCGACTGGTTCGGGCAAGACCTATCTGGCGCAGTCGC
TCGCCCGGATGCTCGATGTGCCTTTCGCCATTGCTGACGCCACCAGTTTGACCGAAGCCGGCTACGTCGGTGAAGACGTA
GAGAATATCCTGCTGAAGCTTCTCCAGGCCGCCGACTTTGACGTGGCGAAGGCCCAGCGCGGCATCATCTACGTCGACGA
GGTGGACAAGATCTCCCGCAAGTCGGAGAACCCGTCCATCACCCGCGATGTATCCGGCGAGGGCGTGCAGCAGGCCCTGC
TGAAGATCCTGGAAGGCACCGTTGCCGCCGTGCCGCCGCAGGGAGGCCGCAAGCACCCGAACCAGGAGTTCATCCAGTTC
GACACGAAGAACGTGCTGTTCATCGTGGCGGGTGCGTTCTCCGGGTTGGAGAAGGTCATCTCCGAGCGCCGCGGCAAGAA
GGGTCTGGGTTTCGGCGCGGAGATCAGCGCGAAGTCCGAGGAGGATCCGAACCCGTTCCAGTTCGTGGAGCCGGAGGACC
TGGTGAAGTTCGGTTTGATCCCCGAGCTGATCGGCCGCCTGCCGGTACTGACCCACGTTGGCCACCTGGACGAGGACGCC
CTTGTGCGCGTACTCACCGAGCCGAAGAACTCCCTAGTGCGCCAGTACCAGCGCCTGTTCGACATGGACGGTGTGCGCCT
GACCTTCGAGGACGAGGCGCTGCGGGAGATCGCCCAAAAGGCGCTGGCGCGCGAGACTGGCGCCCGCGGCCTGCGGTCCA
TCATGGAAACCCTGCTGCTGCCGACCATGTTCGCCATTCCGGAAGATGAGGAAACCGGCGAGGTCATCATCACCGGTGCA
TGTGCCCGCGGGGAAGCGGAACCGACCCTGCTGACCCACGAAGAGGTCGCCAAGCGGGATAAGAAGAGCGCCTAG

Upstream 100 bases:

>100_bases
CGCGGGGTTTTTGGTGTGGCGCAGTAGAATTGAAGGCCTACGAGGGTGCTAATCTAGCTGTCCCGCAAGTTACCCGACCC
AAGAAAGCCTGATTTCCCGC

Downstream 100 bases:

>100_bases
TCGTGATATAGGTCCGATGGCGCCGAGGGGGCGTCATCAACCTCTTCATCCTCGTGCCGCGCATGGTGGTAGAGCGACGC
GGCGACCGAGGTACCAATCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MPESAELLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELLAVDPAESSAKLPKPAAIAEFLDSYVIGQDEAK
RTLAVAVYNHYKRIQVEESNAAARRSDDEVELAKSNILMLGPTGSGKTYLAQSLARMLDVPFAIADATSLTEAGYVGEDV
ENILLKLLQAADFDVAKAQRGIIYVDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPNQEFIQF
DTKNVLFIVAGAFSGLEKVISERRGKKGLGFGAEISAKSEEDPNPFQFVEPEDLVKFGLIPELIGRLPVLTHVGHLDEDA
LVRVLTEPKNSLVRQYQRLFDMDGVRLTFEDEALREIAQKALARETGARGLRSIMETLLLPTMFAIPEDEETGEVIITGA
CARGEAEPTLLTHEEVAKRDKKSA

Sequences:

>Translated_424_residues
MPESAELLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELLAVDPAESSAKLPKPAAIAEFLDSYVIGQDEAK
RTLAVAVYNHYKRIQVEESNAAARRSDDEVELAKSNILMLGPTGSGKTYLAQSLARMLDVPFAIADATSLTEAGYVGEDV
ENILLKLLQAADFDVAKAQRGIIYVDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPNQEFIQF
DTKNVLFIVAGAFSGLEKVISERRGKKGLGFGAEISAKSEEDPNPFQFVEPEDLVKFGLIPELIGRLPVLTHVGHLDEDA
LVRVLTEPKNSLVRQYQRLFDMDGVRLTFEDEALREIAQKALARETGARGLRSIMETLLLPTMFAIPEDEETGEVIITGA
CARGEAEPTLLTHEEVAKRDKKSA
>Mature_423_residues
PESAELLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELLAVDPAESSAKLPKPAAIAEFLDSYVIGQDEAKR
TLAVAVYNHYKRIQVEESNAAARRSDDEVELAKSNILMLGPTGSGKTYLAQSLARMLDVPFAIADATSLTEAGYVGEDVE
NILLKLLQAADFDVAKAQRGIIYVDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPNQEFIQFD
TKNVLFIVAGAFSGLEKVISERRGKKGLGFGAEISAKSEEDPNPFQFVEPEDLVKFGLIPELIGRLPVLTHVGHLDEDAL
VRVLTEPKNSLVRQYQRLFDMDGVRLTFEDEALREIAQKALARETGARGLRSIMETLLLPTMFAIPEDEETGEVIITGAC
ARGEAEPTLLTHEEVAKRDKKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=310, Percent_Identity=51.9354838709677, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=411, Percent_Identity=62.5304136253041, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=110, Percent_Identity=42.7272727272727, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=293, Percent_Identity=49.4880546075085, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71982905, Length=295, Percent_Identity=49.8305084745763, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=38.0462724935733, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40.8, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=411, Percent_Identity=40.3892944038929, Blast_Score=276, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24648291, Length=322, Percent_Identity=49.0683229813665, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24648289, Length=322, Percent_Identity=49.0683229813665, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46393; Mature: 46262

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESAELLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELLAVDPAESSAKLP
CCCCHHHHEEHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KPAAIAEFLDSYVIGQDEAKRTLAVAVYNHYKRIQVEESNAAARRSDDEVELAKSNILML
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCHHCCCCCHHHHHHCCEEEE
GPTGSGKTYLAQSLARMLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVAKAQR
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIIYVDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPNQEFIQF
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHEE
DTKNVLFIVAGAFSGLEKVISERRGKKGLGFGAEISAKSEEDPNPFQFVEPEDLVKFGLI
CCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCH
PELIGRLPVLTHVGHLDEDALVRVLTEPKNSLVRQYQRLFDMDGVRLTFEDEALREIAQK
HHHHCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
ALARETGARGLRSIMETLLLPTMFAIPEDEETGEVIITGACARGEAEPTLLTHEEVAKRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEECHHHHHHHH
KKSA
CCCC
>Mature Secondary Structure 
PESAELLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELLAVDPAESSAKLP
CCCHHHHEEHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KPAAIAEFLDSYVIGQDEAKRTLAVAVYNHYKRIQVEESNAAARRSDDEVELAKSNILML
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCHHCCCCCHHHHHHCCEEEE
GPTGSGKTYLAQSLARMLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVAKAQR
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIIYVDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPNQEFIQF
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHEE
DTKNVLFIVAGAFSGLEKVISERRGKKGLGFGAEISAKSEEDPNPFQFVEPEDLVKFGLI
CCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCH
PELIGRLPVLTHVGHLDEDALVRVLTEPKNSLVRQYQRLFDMDGVRLTFEDEALREIAQK
HHHHCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
ALARETGARGLRSIMETLLLPTMFAIPEDEETGEVIITGACARGEAEPTLLTHEEVAKRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEECHHHHHHHH
KKSA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA