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The map label for this gene is purL [H]

Identifier: 68535420

GI number: 68535420

Start: 425618

End: 428137

Strand: Direct

Name: purL [H]

Synonym: jk0355

Alternate gene names: 68535420

Gene position: 425618-428137 (Clockwise)

Preceding gene: 68535419

Following gene: 68535422

Centisome position: 17.28

GC content: 66.03

Gene sequence:

>2520_bases
ATGGCCTGGGGCTGTTCCAGTCCGTTCTGTCTACGCTCGTTTCCTAATCTTTTTTCTTACAAGGAGCACCCGATCCTCAT
GATTCACAACGACACGGTCGCCGATGCTAAGGCCAACCCGGACCTGGAGCAGCCGTATCACGAGCTGGGCCTAAAGGACG
ACGAGTACGCGCGCATCAAGGAACTGCTGGGCCGCCGCCCGACCGATGCGGAGCTGGCCATGTACTCCGTCATGTGGTCC
GAGCACTGCTCGTACAAGTCCTCGAAGACGCACCTGCGTTACTTCGGCGAGACCACGACCGAAGAGATGAAGTCCAAGAT
GCTCGCCGGTATCGGTGAGAACGCTGGCGTGATCGACATCGGCGATGGCCACGCGGTGACCTTCAAGGTCGAGTCCCACA
ACCACCCCTCCTACGTGGAGCCCTACCAGGGCGCAGCCACCGGCGTGGGCGGTATCGTCCGCGACATCATGGCAATGGGC
GCGCGCCCGGTGGCTGTGATGGACCAGCTGCGCTTCGGCCCGGCCGACCTGCCGGATACCCAGCGCGTGCTGCCCGGCGT
GGTCGCGGGTGTGGGCGGTTATGGCAACTCTCTGGGGCTGCCGAACATTGGCGGCGAGACTGTTTTTGACGCCACCTACG
CGGGTAACCCGTTGGTAAATGCACTGTGCGTGGGCACTTTGAAGACCGAAGACCTCAAGCTGGCCTTCGCCTCTGGCAAG
GGCAACCGAGTGATCCTTTTCGGCTCCCGCACGGGCTTGGACGGCATCGGTGGCGTGTCTGTGCTGGCCTCGGACACCTT
CGAGGAAGGCGCGGAGCGCAAGCTGCCCGCCGTGCAGGTGGGCGACCCCTTCGCGGAGAAGGTACTGATCGAGTGCTGCC
TGGACCTGTACCGCGCCAACGTGGTGGTGGGTATTCAGGACCTCGGCGGCGCCGGGCTTTCCTGCGCCACTGCAGAGCTG
GCTTCCGCCGGTGACGGCGGCATGCACATCAACCTGGACAATGTGCACCTGCGCGCTGAGGGCATGACCGCCGCGGAGAT
CTTGTCCTCCGAGTCGCAGGAGCGCATGTGCGCCGTGGTGGAGCCGGAGAACGTGGATGCGTTCATGGAAATCTGCCGCA
AGTGGGACGTGCTGGCCTCCGACATCGGCTGCGTAACCGATGGCGAGCACCTCGTCATCGAGCACTGCGGCGAGATTGTG
GTGGACGCTTCGGCACACACCATGGCCGAAGAAGGCCCGGTCTACGAGCGCCCCTACGAGCGCCCGGCGGAGCAGGACGA
GCTGAACGAGCCCCGCGGCGTGGAGTTGCCGGAGACCTCCCAGGAGGTCCGTCAACAGATCCTGGACCTGGCGGCCTCCC
CGGCGCTGTGCTCCCGCGAGTTCATCACCGAGCAGTACGACCGTTACGTGCGCGGCAACACCGTCGCGGCCAAGGACGCG
GACGCGGGCGTGCTACGCATCGACGAGGAGACCGGGCGCGGCATCGCCGTGTCTACTGACGCCTCCGGCCGTTACGCCCG
CCTGGACCCGCGCACCGGCGCACAGTTGGCGCTGGCCGAGGCATACCGCAACGTCTCCGTCACGGGTGCGACCCCCGTGG
CGGTCTCCAACTGCCTGAACTTCGGCTCCCCGGAGGACCCGGGCGTGATGTGGCAGTTCCGCGAGGCCGTTCACGGCCTG
GCCGATGGCTGTAAGGAAATGGGCATTCCGGTGACGGGCGGCAACGTTTCGTTCTACAACCAGACCGGCGATACCGCTAT
CCTGCCGACCCCGGTTATCGCAGTGCTGGGCACCATCGACGATTGTGCTCGCCGCATCCCGCAGCAGCTGCCGAAGCAGG
CTGGTGCCGAGGCCGGCGCCGACGAGAGCCAGGAACAGTACCACCTGGTTCTGGTGGGCGCGGAGACCCGCGAGGAGCTC
GGCGGTTCCATCTGGCAGCAGGTTGTTCACGACGAGCTGGCCGGCCTGCCCCCGCAGGTTGACCTGTCCGTGGAACAGCG
CCTGGGCGCCTTCATCACCGACCAGCGCGACAAGATCGTCGCCGCCCACGACCTCTCCGAGGGCGGCCTGTCGCAGGCCG
TTGTGGAGCTGGCAATCCAGTCCGGTCGGGGAATGGCTGTGAACCCGATGCTCAGCCAGCACGAATCCGCCGTCGCGCAG
GGTCGCACGCTGGCACAGCAAGCGGCGGTTGGCCTGTTCTCCGAGACCGCTTCCCGCGTCCTGCTGGCCGTGCGCAGCGA
GGACTACGGCGATCTGATGCGCGACCTGGCCGAGACCGGCCTGACCGGCGGGTGGATCGGCCTGACCGGTGTCAGTGACG
CAGCTGGTCAGCCGGTCATCCGCTTCGGCTCCGGCGTGTACCCGGTGCTGCCGTTCGGCGGGGAGATCGAGCTCGACCCG
GCCAAGCAGCATGATGATGACTTCGACATCGTCATCTCGCTGGATGAGGCCGAGACGGCGTGGAAGTCCACCCTGCCCGC
GTTGTTTAGCCACGCGGCCGGCAACAATTCTGTGATCTAG

Upstream 100 bases:

>100_bases
CGCAACTCGATCGCCGGAGTGTGCAGCGAAAACGGTCGCGTGGTTGGCCTTATGCCGCACCCGGAGCACGCCGTGGAAAC
CCTGACCGGCCCGTCCTTGG

Downstream 100 bases:

>100_bases
GTAGCCGCGACAAGTAATCAAGGGGCCCACGACCAGATGGTCGCGGGCCCCTTGCCTTGTGCTGTGGCGTGTTGCCGCCG
CGCTTTACTCTACGAAGCGG

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 839; Mature: 838

Protein sequence:

>839_residues
MAWGCSSPFCLRSFPNLFSYKEHPILMIHNDTVADAKANPDLEQPYHELGLKDDEYARIKELLGRRPTDAELAMYSVMWS
EHCSYKSSKTHLRYFGETTTEEMKSKMLAGIGENAGVIDIGDGHAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMG
ARPVAVMDQLRFGPADLPDTQRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPLVNALCVGTLKTEDLKLAFASGK
GNRVILFGSRTGLDGIGGVSVLASDTFEEGAERKLPAVQVGDPFAEKVLIECCLDLYRANVVVGIQDLGGAGLSCATAEL
ASAGDGGMHINLDNVHLRAEGMTAAEILSSESQERMCAVVEPENVDAFMEICRKWDVLASDIGCVTDGEHLVIEHCGEIV
VDASAHTMAEEGPVYERPYERPAEQDELNEPRGVELPETSQEVRQQILDLAASPALCSREFITEQYDRYVRGNTVAAKDA
DAGVLRIDEETGRGIAVSTDASGRYARLDPRTGAQLALAEAYRNVSVTGATPVAVSNCLNFGSPEDPGVMWQFREAVHGL
ADGCKEMGIPVTGGNVSFYNQTGDTAILPTPVIAVLGTIDDCARRIPQQLPKQAGAEAGADESQEQYHLVLVGAETREEL
GGSIWQQVVHDELAGLPPQVDLSVEQRLGAFITDQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAVNPMLSQHESAVAQ
GRTLAQQAAVGLFSETASRVLLAVRSEDYGDLMRDLAETGLTGGWIGLTGVSDAAGQPVIRFGSGVYPVLPFGGEIELDP
AKQHDDDFDIVISLDEAETAWKSTLPALFSHAAGNNSVI

Sequences:

>Translated_839_residues
MAWGCSSPFCLRSFPNLFSYKEHPILMIHNDTVADAKANPDLEQPYHELGLKDDEYARIKELLGRRPTDAELAMYSVMWS
EHCSYKSSKTHLRYFGETTTEEMKSKMLAGIGENAGVIDIGDGHAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMG
ARPVAVMDQLRFGPADLPDTQRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPLVNALCVGTLKTEDLKLAFASGK
GNRVILFGSRTGLDGIGGVSVLASDTFEEGAERKLPAVQVGDPFAEKVLIECCLDLYRANVVVGIQDLGGAGLSCATAEL
ASAGDGGMHINLDNVHLRAEGMTAAEILSSESQERMCAVVEPENVDAFMEICRKWDVLASDIGCVTDGEHLVIEHCGEIV
VDASAHTMAEEGPVYERPYERPAEQDELNEPRGVELPETSQEVRQQILDLAASPALCSREFITEQYDRYVRGNTVAAKDA
DAGVLRIDEETGRGIAVSTDASGRYARLDPRTGAQLALAEAYRNVSVTGATPVAVSNCLNFGSPEDPGVMWQFREAVHGL
ADGCKEMGIPVTGGNVSFYNQTGDTAILPTPVIAVLGTIDDCARRIPQQLPKQAGAEAGADESQEQYHLVLVGAETREEL
GGSIWQQVVHDELAGLPPQVDLSVEQRLGAFITDQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAVNPMLSQHESAVAQ
GRTLAQQAAVGLFSETASRVLLAVRSEDYGDLMRDLAETGLTGGWIGLTGVSDAAGQPVIRFGSGVYPVLPFGGEIELDP
AKQHDDDFDIVISLDEAETAWKSTLPALFSHAAGNNSVI
>Mature_838_residues
AWGCSSPFCLRSFPNLFSYKEHPILMIHNDTVADAKANPDLEQPYHELGLKDDEYARIKELLGRRPTDAELAMYSVMWSE
HCSYKSSKTHLRYFGETTTEEMKSKMLAGIGENAGVIDIGDGHAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGA
RPVAVMDQLRFGPADLPDTQRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPLVNALCVGTLKTEDLKLAFASGKG
NRVILFGSRTGLDGIGGVSVLASDTFEEGAERKLPAVQVGDPFAEKVLIECCLDLYRANVVVGIQDLGGAGLSCATAELA
SAGDGGMHINLDNVHLRAEGMTAAEILSSESQERMCAVVEPENVDAFMEICRKWDVLASDIGCVTDGEHLVIEHCGEIVV
DASAHTMAEEGPVYERPYERPAEQDELNEPRGVELPETSQEVRQQILDLAASPALCSREFITEQYDRYVRGNTVAAKDAD
AGVLRIDEETGRGIAVSTDASGRYARLDPRTGAQLALAEAYRNVSVTGATPVAVSNCLNFGSPEDPGVMWQFREAVHGLA
DGCKEMGIPVTGGNVSFYNQTGDTAILPTPVIAVLGTIDDCARRIPQQLPKQAGAEAGADESQEQYHLVLVGAETREELG
GSIWQQVVHDELAGLPPQVDLSVEQRLGAFITDQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAVNPMLSQHESAVAQG
RTLAQQAAVGLFSETASRVLLAVRSEDYGDLMRDLAETGLTGGWIGLTGVSDAAGQPVIRFGSGVYPVLPFGGEIELDPA
KQHDDDFDIVISLDEAETAWKSTLPALFSHAAGNNSVI

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=668, Percent_Identity=24.4011976047904, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI48994899, Length=813, Percent_Identity=25.2152521525215, Blast_Score=125, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17553022, Length=657, Percent_Identity=24.3531202435312, Blast_Score=102, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321498, Length=898, Percent_Identity=24.9443207126949, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24582111, Length=654, Percent_Identity=26.2996941896024, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24582109, Length=654, Percent_Identity=26.2996941896024, Blast_Score=126, Evalue=7e-29,
Organism=Drosophila melanogaster, GI17137292, Length=654, Percent_Identity=26.2996941896024, Blast_Score=126, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 89496; Mature: 89365

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWGCSSPFCLRSFPNLFSYKEHPILMIHNDTVADAKANPDLEQPYHELGLKDDEYARIK
CCCCCCCCHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCHHHHHH
ELLGRRPTDAELAMYSVMWSEHCSYKSSKTHLRYFGETTTEEMKSKMLAGIGENAGVIDI
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEC
GDGHAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGPADLPDT
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
QRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPLVNALCVGTLKTEDLKLAFASGK
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHEEECCCCCCEEEEEECCC
GNRVILFGSRTGLDGIGGVSVLASDTFEEGAERKLPAVQVGDPFAEKVLIECCLDLYRAN
CCEEEEEECCCCCCCCCCHHHEECCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCC
VVVGIQDLGGAGLSCATAELASAGDGGMHINLDNVHLRAEGMTAAEILSSESQERMCAVV
EEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCEEEEECCCHHHHHHCCCCHHCEEEEE
EPENVDAFMEICRKWDVLASDIGCVTDGEHLVIEHCGEIVVDASAHTMAEEGPVYERPYE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEECCCHHHHHHCCCCCCCCCC
RPAEQDELNEPRGVELPETSQEVRQQILDLAASPALCSREFITEQYDRYVRGNTVAAKDA
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCC
DAGVLRIDEETGRGIAVSTDASGRYARLDPRTGAQLALAEAYRNVSVTGATPVAVSNCLN
CCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHCCCEECCCCHHHHHHHHC
FGSPEDPGVMWQFREAVHGLADGCKEMGIPVTGGNVSFYNQTGDTAILPTPVIAVLGTID
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCEECCCHHHHHHCCHH
DCARRIPQQLPKQAGAEAGADESQEQYHLVLVGAETREELGGSIWQQVVHDELAGLPPQV
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DLSVEQRLGAFITDQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAVNPMLSQHESAVAQ
CCCHHHHCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHH
GRTLAQQAAVGLFSETASRVLLAVRSEDYGDLMRDLAETGLTGGWIGLTGVSDAAGQPVI
HHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCE
RFGSGVYPVLPFGGEIELDPAKQHDDDFDIVISLDEAETAWKSTLPALFSHAAGNNSVI
EECCCCCEEECCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AWGCSSPFCLRSFPNLFSYKEHPILMIHNDTVADAKANPDLEQPYHELGLKDDEYARIK
CCCCCCCHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCHHHHHH
ELLGRRPTDAELAMYSVMWSEHCSYKSSKTHLRYFGETTTEEMKSKMLAGIGENAGVIDI
HHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEC
GDGHAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGPADLPDT
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCH
QRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPLVNALCVGTLKTEDLKLAFASGK
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHEEECCCCCCEEEEEECCC
GNRVILFGSRTGLDGIGGVSVLASDTFEEGAERKLPAVQVGDPFAEKVLIECCLDLYRAN
CCEEEEEECCCCCCCCCCHHHEECCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCC
VVVGIQDLGGAGLSCATAELASAGDGGMHINLDNVHLRAEGMTAAEILSSESQERMCAVV
EEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCEEEEECCCHHHHHHCCCCHHCEEEEE
EPENVDAFMEICRKWDVLASDIGCVTDGEHLVIEHCGEIVVDASAHTMAEEGPVYERPYE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEECCCHHHHHHCCCCCCCCCC
RPAEQDELNEPRGVELPETSQEVRQQILDLAASPALCSREFITEQYDRYVRGNTVAAKDA
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCC
DAGVLRIDEETGRGIAVSTDASGRYARLDPRTGAQLALAEAYRNVSVTGATPVAVSNCLN
CCCEEEEECCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHCCCEECCCCHHHHHHHHC
FGSPEDPGVMWQFREAVHGLADGCKEMGIPVTGGNVSFYNQTGDTAILPTPVIAVLGTID
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCEECCCHHHHHHCCHH
DCARRIPQQLPKQAGAEAGADESQEQYHLVLVGAETREELGGSIWQQVVHDELAGLPPQV
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DLSVEQRLGAFITDQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAVNPMLSQHESAVAQ
CCCHHHHCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHH
GRTLAQQAAVGLFSETASRVLLAVRSEDYGDLMRDLAETGLTGGWIGLTGVSDAAGQPVI
HHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCE
RFGSGVYPVLPFGGEIELDPAKQHDDDFDIVISLDEAETAWKSTLPALFSHAAGNNSVI
EECCCCCEEECCCCEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA