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The map label for this gene is cysH [H]

Identifier: 68535310

GI number: 68535310

Start: 302457

End: 303257

Strand: Direct

Name: cysH [H]

Synonym: jk0245

Alternate gene names: 68535310

Gene position: 302457-303257 (Clockwise)

Preceding gene: 68535309

Following gene: 68535311

Centisome position: 12.28

GC content: 64.04

Gene sequence:

>801_bases
ATGAGCCTGGTAGATGCGACCGGCCTGCTCGGCGGGAATTCGGATGACTTCCGAGACCCAGCCGAGAGTCCGCAGGGCGC
GCCAACCAAGACCACACCGCTGAGCGACGAGGAGCGAGCAGCCAACGAGCAGCTCGTCGCCGAGTGGAACGACAAGCTAG
AGGGCGCCAGCGCCGAAGAGATCATGGAATGGGTAGCCGAGCACGTACCTGGCAAGGTTGCCGTGACCATGTCGATGCAG
GACACCGTCCTGGCCGAGCTGGCGGAAGGCCGCCTGGCGGAAGACCGTGCAGAGCTGGTCTTCCTGGATACCGGCTATCA
CTTTGCCGAAACGCTCGAGACCCGCGATAAGGTCCAGCAGCGCTACAACCTGCCGCTGGAGAACATCACCCCGGTCCTCA
ACCGCGAGGAGCAGGACAAGGTCTACGGCCCGCGCCTGTACTCCCGCGACAACACCGCCTGCTGCCGCATGCGCAAGGTC
GAGCCGTTGGCCCGAATGCTGAACCCTTTCAACGCCTGGATCACCGGCGTGCGCCGCGTAGACAACGCCCTGCGCGCCAA
CACCCCGGTGCTGGATGTGGATCGCACCGGGCGGCTGAAAATCAACCCCATCGTCGCCTGGAGTGACGAGGACGTGGAGG
CGTACATCAACGACCACGACCTGATCATCAACCCCTTGACCAAGCAGGGCTACCCGTCGATCGGCTGCGAAACCTGCACC
TTGCCAGTTGCCCCAGGACAGGACCCCCGATCCGGCCGCTGGGCCGGCTCCAACAAGACAGAATGCGGACTTCACACATG
A

Upstream 100 bases:

>100_bases
CAGACCGATCGGTCTGTCTAGGGAATAAGCAAGAGTTCCCCCGAGTTCTTAAGAAGCACACTTCGACAAACCAACTATCA
ACCCCCGAGAAGAGGAGCTC

Downstream 100 bases:

>100_bases
GCAATGAAAACACCACCGCCCTCTCGCCGCACCTGGCGAGCCTCGAGGCGGAAGCAATCGAGATCCTGCGCGAAGTAGCA
GGCCAGTTCGACCGCCCCGC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSLVDATGLLGGNSDDFRDPAESPQGAPTKTTPLSDEERAANEQLVAEWNDKLEGASAEEIMEWVAEHVPGKVAVTMSMQ
DTVLAELAEGRLAEDRAELVFLDTGYHFAETLETRDKVQQRYNLPLENITPVLNREEQDKVYGPRLYSRDNTACCRMRKV
EPLARMLNPFNAWITGVRRVDNALRANTPVLDVDRTGRLKINPIVAWSDEDVEAYINDHDLIINPLTKQGYPSIGCETCT
LPVAPGQDPRSGRWAGSNKTECGLHT

Sequences:

>Translated_266_residues
MSLVDATGLLGGNSDDFRDPAESPQGAPTKTTPLSDEERAANEQLVAEWNDKLEGASAEEIMEWVAEHVPGKVAVTMSMQ
DTVLAELAEGRLAEDRAELVFLDTGYHFAETLETRDKVQQRYNLPLENITPVLNREEQDKVYGPRLYSRDNTACCRMRKV
EPLARMLNPFNAWITGVRRVDNALRANTPVLDVDRTGRLKINPIVAWSDEDVEAYINDHDLIINPLTKQGYPSIGCETCT
LPVAPGQDPRSGRWAGSNKTECGLHT
>Mature_265_residues
SLVDATGLLGGNSDDFRDPAESPQGAPTKTTPLSDEERAANEQLVAEWNDKLEGASAEEIMEWVAEHVPGKVAVTMSMQD
TVLAELAEGRLAEDRAELVFLDTGYHFAETLETRDKVQQRYNLPLENITPVLNREEQDKVYGPRLYSRDNTACCRMRKVE
PLARMLNPFNAWITGVRRVDNALRANTPVLDVDRTGRLKINPIVAWSDEDVEAYINDHDLIINPLTKQGYPSIGCETCTL
PVAPGQDPRSGRWAGSNKTECGLHT

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=225, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325425, Length=251, Percent_Identity=32.2709163346614, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29563; Mature: 29432

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVDATGLLGGNSDDFRDPAESPQGAPTKTTPLSDEERAANEQLVAEWNDKLEGASAEE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IMEWVAEHVPGKVAVTMSMQDTVLAELAEGRLAEDRAELVFLDTGYHFAETLETRDKVQQ
HHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
RYNLPLENITPVLNREEQDKVYGPRLYSRDNTACCRMRKVEPLARMLNPFNAWITGVRRV
HHCCCHHHCCHHHCCCCCHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNALRANTPVLDVDRTGRLKINPIVAWSDEDVEAYINDHDLIINPLTKQGYPSIGCETCT
HHHHHCCCCEEECCCCCCEEEEEEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
LPVAPGQDPRSGRWAGSNKTECGLHT
ECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLVDATGLLGGNSDDFRDPAESPQGAPTKTTPLSDEERAANEQLVAEWNDKLEGASAEE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IMEWVAEHVPGKVAVTMSMQDTVLAELAEGRLAEDRAELVFLDTGYHFAETLETRDKVQQ
HHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
RYNLPLENITPVLNREEQDKVYGPRLYSRDNTACCRMRKVEPLARMLNPFNAWITGVRRV
HHCCCHHHCCHHHCCCCCHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNALRANTPVLDVDRTGRLKINPIVAWSDEDVEAYINDHDLIINPLTKQGYPSIGCETCT
HHHHHCCCCEEECCCCCCEEEEEEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCEEE
LPVAPGQDPRSGRWAGSNKTECGLHT
ECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA