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The map label for this gene is udgA [H]

Identifier: 68535238

GI number: 68535238

Start: 216017

End: 217378

Strand: Direct

Name: udgA [H]

Synonym: jk0173

Alternate gene names: 68535238

Gene position: 216017-217378 (Clockwise)

Preceding gene: 68535235

Following gene: 68535239

Centisome position: 8.77

GC content: 64.9

Gene sequence:

>1362_bases
ATGCGTATGACAGTGTTTGGAACGGGATACCTTGGCGCAACCCACGCCGCCTGCATGGCCGAAATGGGCCACGACGTGCT
CGGAGTCGATGTCGACCCGCAGAAGATCCAAGCTCTTTCCGAAGGGCGCGTGCCCTTCTTCGAACCCGGCCTGCCGGAGA
TCCTCACCCGCAACATCGAAGCCGGCCGTCTGCGTTTCACTACCGACTACGCCGAAGCCGCCGAGTTCGCCGACGTGCAC
TTCATCGGCGTGGGCACCCCGCAGCGCAAGGGCTCCTATGCCGCGGATACCACCTATGTAAATGCCGTCATCGAAACGCT
CGCCCCACTGGTAAGCGGCAACCACACCATCTTCGGCAAGTCCACCGTCCCGGTGGGCACTGCGCACGAGCTGCAGCAGA
AGGCTGATGAGATCGTGGCGGCGTCACCAAACGAAGCCCAAATCACCATCGCGTGGAACCCCGAGTTCCTGCGCGAAGGC
CACGCGGTGAAAGACACGCTGCACCCCGACCGCATCGTCCTGGGCCTGGGCGGCGTTAGCACCAACAGTGACGACCGCAC
TGAGCAGCAGCGTGTAGAGGACCTCGCCCGCGAAATTTACGCCCCCGCACTCGAGGAGGGCACCCCGTTCCTGGTGATGG
ACCTGCCGACCGCGGAGCTGGTCAAGGTCTCCGCGAACGCCTTCCTGGCCACCAAGATCTCCTTCATCAACGCTGTCTCT
GAGCTGTGCGAGATCGTCGGCGCGGACGTCACCGCACTAGCCGACGCGATTGGCATGGACGACCGCATCGGGCGCAAGTT
CCTCGGCGCCGGCCTGGGCTTCGGCGGCGGTTGCCTGCCGAAGGATATTCGCGCGTTCATGGCGCGCGCAGGTGAGCTCG
GCGCGGACCAGGCTCTGACGTTCCTTCGTGAGGTGGACGCCATCAACATGCGCCGCCGCGAGAAGACAGTAGAGCTGGCG
CGCGAGACGCTGGGCGGCTCCCTGATCGGCCGGAACGTGACGGTCCTCGGCGCGGCCTTCAAACCCAACAGTGACGACGT
GCGCGATTCCCCGGCGTTGTCCGTGGCCGGTTCGCTATCGCTGAGCGGCGCAAACGTCACCGTGTACGACCCGCAGGGTA
TGGAGAACGCCGCGAAGATCTTCCCGACGCTGACCTACGCGCCGAACGTAGAGGAAGCCCTCGAAGGCGCGGAGATCGTG
ATCGTGGCAACCGAGTGGAAGCAGTTCCAAGAACTCGACCCGGTAGTCGCCCGCAAGCTGGTAGCCGGGGACAACCCCGC
CGTGCTGGACGGTCGCAATTGCCTACCACGCAAGGAATGGGAAGCCGCGGGCTGGAACTTCCTGGCACTGGGGCGGGGCT
AG

Upstream 100 bases:

>100_bases
TTGATGCTCATTCGCGCCTGAGTGCAGTTAACCAAACGCTGCGCAGAAGATCACCTGAGGGTCACCTCCTGTTCACCTGT
CAATTGTAAATTTGCCTGTT

Downstream 100 bases:

>100_bases
TACACGGCTAGCTGGCTGCGCACAGCCCCACACCCGCTAGGCTATAGAGCGTGTTACTTTCAGACCGAGACATCCGCGCC
GCCATCAACTCCGGCGAGCT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MRMTVFGTGYLGATHAACMAEMGHDVLGVDVDPQKIQALSEGRVPFFEPGLPEILTRNIEAGRLRFTTDYAEAAEFADVH
FIGVGTPQRKGSYAADTTYVNAVIETLAPLVSGNHTIFGKSTVPVGTAHELQQKADEIVAASPNEAQITIAWNPEFLREG
HAVKDTLHPDRIVLGLGGVSTNSDDRTEQQRVEDLAREIYAPALEEGTPFLVMDLPTAELVKVSANAFLATKISFINAVS
ELCEIVGADVTALADAIGMDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDAINMRRREKTVELA
RETLGGSLIGRNVTVLGAAFKPNSDDVRDSPALSVAGSLSLSGANVTVYDPQGMENAAKIFPTLTYAPNVEEALEGAEIV
IVATEWKQFQELDPVVARKLVAGDNPAVLDGRNCLPRKEWEAAGWNFLALGRG

Sequences:

>Translated_453_residues
MRMTVFGTGYLGATHAACMAEMGHDVLGVDVDPQKIQALSEGRVPFFEPGLPEILTRNIEAGRLRFTTDYAEAAEFADVH
FIGVGTPQRKGSYAADTTYVNAVIETLAPLVSGNHTIFGKSTVPVGTAHELQQKADEIVAASPNEAQITIAWNPEFLREG
HAVKDTLHPDRIVLGLGGVSTNSDDRTEQQRVEDLAREIYAPALEEGTPFLVMDLPTAELVKVSANAFLATKISFINAVS
ELCEIVGADVTALADAIGMDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDAINMRRREKTVELA
RETLGGSLIGRNVTVLGAAFKPNSDDVRDSPALSVAGSLSLSGANVTVYDPQGMENAAKIFPTLTYAPNVEEALEGAEIV
IVATEWKQFQELDPVVARKLVAGDNPAVLDGRNCLPRKEWEAAGWNFLALGRG
>Mature_453_residues
MRMTVFGTGYLGATHAACMAEMGHDVLGVDVDPQKIQALSEGRVPFFEPGLPEILTRNIEAGRLRFTTDYAEAAEFADVH
FIGVGTPQRKGSYAADTTYVNAVIETLAPLVSGNHTIFGKSTVPVGTAHELQQKADEIVAASPNEAQITIAWNPEFLREG
HAVKDTLHPDRIVLGLGGVSTNSDDRTEQQRVEDLAREIYAPALEEGTPFLVMDLPTAELVKVSANAFLATKISFINAVS
ELCEIVGADVTALADAIGMDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDAINMRRREKTVELA
RETLGGSLIGRNVTVLGAAFKPNSDDVRDSPALSVAGSLSLSGANVTVYDPQGMENAAKIFPTLTYAPNVEEALEGAEIV
IVATEWKQFQELDPVVARKLVAGDNPAVLDGRNCLPRKEWEAAGWNFLALGRG

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=478, Percent_Identity=32.0083682008368, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI296040438, Length=379, Percent_Identity=32.1899736147757, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI296040443, Length=325, Percent_Identity=32.9230769230769, Blast_Score=170, Evalue=3e-42,
Organism=Escherichia coli, GI1788340, Length=432, Percent_Identity=25, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI48994968, Length=439, Percent_Identity=25.5125284738041, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=475, Percent_Identity=33.6842105263158, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17136908, Length=480, Percent_Identity=31.875, Blast_Score=214, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48476; Mature: 48476

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTVFGTGYLGATHAACMAEMGHDVLGVDVDPQKIQALSEGRVPFFEPGLPEILTRNIE
CEEEEEECCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHCCCC
AGRLRFTTDYAEAAEFADVHFIGVGTPQRKGSYAADTTYVNAVIETLAPLVSGNHTIFGK
CCEEEEEECHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECC
STVPVGTAHELQQKADEIVAASPNEAQITIAWNPEFLREGHAVKDTLHPDRIVLGLGGVS
CCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECHHHHHCCCCHHHCCCCCEEEEEECCCC
TNSDDRTEQQRVEDLAREIYAPALEEGTPFLVMDLPTAELVKVSANAFLATKISFINAVS
CCCCCHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCHHHEEECCCCHHHHHHHHHHHHH
ELCEIVGADVTALADAIGMDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALT
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
FLREVDAINMRRREKTVELARETLGGSLIGRNVTVLGAAFKPNSDDVRDSPALSVAGSLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEEECCCCCCCCCCCCEEEECCEE
LSGANVTVYDPQGMENAAKIFPTLTYAPNVEEALEGAEIVIVATEWKQFQELDPVVARKL
ECCCEEEEECCCCCCCHHHHCEEEECCCCHHHHHCCCEEEEEECCCHHHHHCCHHHHHHH
VAGDNPAVLDGRNCLPRKEWEAAGWNFLALGRG
HCCCCCCEECCCCCCCCCCHHCCCCCEEEECCC
>Mature Secondary Structure
MRMTVFGTGYLGATHAACMAEMGHDVLGVDVDPQKIQALSEGRVPFFEPGLPEILTRNIE
CEEEEEECCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHCCCC
AGRLRFTTDYAEAAEFADVHFIGVGTPQRKGSYAADTTYVNAVIETLAPLVSGNHTIFGK
CCEEEEEECHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECC
STVPVGTAHELQQKADEIVAASPNEAQITIAWNPEFLREGHAVKDTLHPDRIVLGLGGVS
CCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECHHHHHCCCCHHHCCCCCEEEEEECCCC
TNSDDRTEQQRVEDLAREIYAPALEEGTPFLVMDLPTAELVKVSANAFLATKISFINAVS
CCCCCHHHHHHHHHHHHHHHCCHHCCCCCEEEEECCCHHHEEECCCCHHHHHHHHHHHHH
ELCEIVGADVTALADAIGMDDRIGRKFLGAGLGFGGGCLPKDIRAFMARAGELGADQALT
HHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHH
FLREVDAINMRRREKTVELARETLGGSLIGRNVTVLGAAFKPNSDDVRDSPALSVAGSLS
HHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEEEECCCCCCCCCCCCEEEECCEE
LSGANVTVYDPQGMENAAKIFPTLTYAPNVEEALEGAEIVIVATEWKQFQELDPVVARKL
ECCCEEEEECCCCCCCHHHHCEEEECCCCHHHHHCCCEEEEEECCCHHHHHCCHHHHHHH
VAGDNPAVLDGRNCLPRKEWEAAGWNFLALGRG
HCCCCCCEECCCCCCCCCCHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]