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The map label for this gene is orn [H]

Identifier: 66768271

GI number: 66768271

Start: 2353827

End: 2354411

Strand: Direct

Name: orn [H]

Synonym: XC_1950

Alternate gene names: 66768271

Gene position: 2353827-2354411 (Clockwise)

Preceding gene: 66768270

Following gene: 66768274

Centisome position: 45.72

GC content: 63.76

Gene sequence:

>585_bases
ATGGCAGACAACGTTGCGGGCAACGACCGACTGATCTGGATCGATCTGGAAATGACCGGCCTGGATACCGATCGCGATTC
GATCATCGAGATCGCCACCATCGTGACCGATGCGCAGTTGAACGTGCTCGCCGAGGGGCCGGAACTGGCCATTGCCCATT
CGCTGGAAACCCTGGAAGCGATGGACGAGTGGAACCGCAACCAGCACCGCCGCTCCGGCCTGTGGCAACGCGTGCTCGAC
AGCCAGGTCACCCACGCGCAAGCCGAGGCGCAGACAGTGGCCTTCCTGAGCGAATGGATCCGCGCCGGCGCCTCGCCGAT
GTGCGGCAATTCGATCTGTCAGGACCGCCGTTTCCTGCACCGCCAGATGTCACGCCTGGAGCGCTACTTCCACTACCGCA
ACCTGGACGTGTCCACCATCAAGGAACTGGCGCGGCGATGGGCACCGGCAGTGGCCTCCGGCTTTGCCAAGAGTTCGGCG
CATACGGCGCTGAGCGACGTACGCGACTCCATCGACGAGCTGCGGCACTACCGGCAGTTCATGGGCACGCTAGGTGGCGA
TAACGGCGGCGGTGTGCAGAACTGA

Upstream 100 bases:

>100_bases
AGCGTGGCAAGCCGCCGCTCGTGCCCTGATCGGCATGGCCGCGGTATGATGCGCGCCCTTTCAGCACCCGGCCGGCAACG
GCCCTCCACAGGACGGTGAT

Downstream 100 bases:

>100_bases
GGTTCCCAACTGGCAACACGGCTGCGAGGCTCCGGCATTCGTGCGGCTAGCGTATCGCTGTACCGCGCACCTATTGACCG
GACACCCGCAGTAACAAAAA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEAMDEWNRNQHRRSGLWQRVLD
SQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSA
HTALSDVRDSIDELRHYRQFMGTLGGDNGGGVQN

Sequences:

>Translated_194_residues
MADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEAMDEWNRNQHRRSGLWQRVLD
SQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSA
HTALSDVRDSIDELRHYRQFMGTLGGDNGGGVQN
>Mature_193_residues
ADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEAMDEWNRNQHRRSGLWQRVLDS
QVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLHRQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSAH
TALSDVRDSIDELRHYRQFMGTLGGDNGGGVQN

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=180, Percent_Identity=43.8888888888889, Blast_Score=167, Evalue=5e-42,
Organism=Escherichia coli, GI87082382, Length=174, Percent_Identity=58.0459770114943, Blast_Score=213, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17557752, Length=170, Percent_Identity=43.5294117647059, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6323088, Length=176, Percent_Identity=39.7727272727273, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355135, Length=179, Percent_Identity=43.5754189944134, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21809; Mature: 21677

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEA
CCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
MDEWNRNQHRRSGLWQRVLDSQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSAHTALSDVRDSIDELRHYRQF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTLGGDNGGGVQN
HHHCCCCCCCCCCC
>Mature Secondary Structure 
ADNVAGNDRLIWIDLEMTGLDTDRDSIIEIATIVTDAQLNVLAEGPELAIAHSLETLEA
CCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
MDEWNRNQHRRSGLWQRVLDSQVTHAQAEAQTVAFLSEWIRAGASPMCGNSICQDRRFLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RQMSRLERYFHYRNLDVSTIKELARRWAPAVASGFAKSSAHTALSDVRDSIDELRHYRQF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGTLGGDNGGGVQN
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]