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The map label for this gene is tagO [H]

Identifier: 66768249

GI number: 66768249

Start: 2326729

End: 2327703

Strand: Direct

Name: tagO [H]

Synonym: XC_1928

Alternate gene names: 66768249

Gene position: 2326729-2327703 (Clockwise)

Preceding gene: 66768248

Following gene: 66768250

Centisome position: 45.19

GC content: 62.67

Gene sequence:

>975_bases
GTGCCGCCGCTCTGGCTGTGGTGCGCGCTACATCTACTGATCGCAGCGCTGGCAACCTGGGGGCTGCGGCGCTATGCGTT
GCACCGGCGCCTGCTCGACCATCCCGGCGAGCGGCGCAGCCATACCGTGGCTACCCCGCGTGGTGGTGGCATGGCTATTG
TCGCTGCGCTCCTGACGGGCTGCCTGGTCGCCTCGTTTGTATGGCCCACCGGGCGTCTATCGATTGCCTGGTTCGCTGCA
GGCTTACTCCTGGTTGCGGGCGTGGGCTGGTGGGACGACCACCGGCCGCTCTCGGCCACACTGCGCTTTGCGATCCATGC
CCTCGCATCGGTGTCGCTTGGCCTGCTGGTGGTACGCCATACAGGGCAACCGCTGGATGGGATCCTCACGGCGTTGGCGT
CGGTGGTGCTGATCAATGTCTGGAATTTCATGGATGGCATCAACGGGCTGGCTTCCAGTCAGGCCGCACTTGCGGGTGCC
GCGTTCGCGCTTGTCGTCCCAGGCAACCTTTCGTGGGCTGGATGGGCACTGACAGCGGCATGTCTTGGATTTCTTCCATT
CAACTTTCCACGCGCGCGCATCTTCCTGGGCGATGGCGGCAGCGGGGCACTCGGTTATGTGCTGGCCGGGCTCCTGGCTT
TGTCAGTGGGAGCGGGGCAGGTGAGTTGGTGGATCGTGTGGTTCCCGTTGACTGCATTTCTTGTCGACGCGGGCTTCACG
CTGCTGTCTCGCATGCTTTCCGGACAGCGCTGGTGGGAGCCTCACGCCTCGCACGTCTATCAACGCCTGGCACGATTGCT
GACCAATCATGTGCCGGTGACCACGGTTTACTTCGCTTTCAGTCTCATCGCTGTTTGCTTGTTTGTCATAATTCGTACCG
ATTCGCGCGGGTGGCTCATGGCTGATGCGGTGGCATGGGGCATCGGCGCAACGGCGATCTGGCAACTTCTGCGCCATGGA
TTGCGCAATTCTTGA

Upstream 100 bases:

>100_bases
GCACCCGCTGCGGGTTCGGTGCCAAGACCCATCACTGGCAATGCCCCAGCTGCAAGGAATGGGGAACCGTCAAGCCGCTG
CTGAACTACGCGGTGGTCTA

Downstream 100 bases:

>100_bases
GTAATGGATTTTTATGATTTCCTGGCGTGATCGTTTGACCAAGTCGCTTCCACAGATCGCCGTGGTCGTCCATGACCTGC
TGATGGTCTGGGTGTGCTGG

Product: lipopolysaccharide core biosynthesis protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MPPLWLWCALHLLIAALATWGLRRYALHRRLLDHPGERRSHTVATPRGGGMAIVAALLTGCLVASFVWPTGRLSIAWFAA
GLLLVAGVGWWDDHRPLSATLRFAIHALASVSLGLLVVRHTGQPLDGILTALASVVLINVWNFMDGINGLASSQAALAGA
AFALVVPGNLSWAGWALTAACLGFLPFNFPRARIFLGDGGSGALGYVLAGLLALSVGAGQVSWWIVWFPLTAFLVDAGFT
LLSRMLSGQRWWEPHASHVYQRLARLLTNHVPVTTVYFAFSLIAVCLFVIIRTDSRGWLMADAVAWGIGATAIWQLLRHG
LRNS

Sequences:

>Translated_324_residues
MPPLWLWCALHLLIAALATWGLRRYALHRRLLDHPGERRSHTVATPRGGGMAIVAALLTGCLVASFVWPTGRLSIAWFAA
GLLLVAGVGWWDDHRPLSATLRFAIHALASVSLGLLVVRHTGQPLDGILTALASVVLINVWNFMDGINGLASSQAALAGA
AFALVVPGNLSWAGWALTAACLGFLPFNFPRARIFLGDGGSGALGYVLAGLLALSVGAGQVSWWIVWFPLTAFLVDAGFT
LLSRMLSGQRWWEPHASHVYQRLARLLTNHVPVTTVYFAFSLIAVCLFVIIRTDSRGWLMADAVAWGIGATAIWQLLRHG
LRNS
>Mature_323_residues
PPLWLWCALHLLIAALATWGLRRYALHRRLLDHPGERRSHTVATPRGGGMAIVAALLTGCLVASFVWPTGRLSIAWFAAG
LLLVAGVGWWDDHRPLSATLRFAIHALASVSLGLLVVRHTGQPLDGILTALASVVLINVWNFMDGINGLASSQAALAGAA
FALVVPGNLSWAGWALTAACLGFLPFNFPRARIFLGDGGSGALGYVLAGLLALSVGAGQVSWWIVWFPLTAFLVDAGFTL
LSRMLSGQRWWEPHASHVYQRLARLLTNHVPVTTVYFAFSLIAVCLFVIIRTDSRGWLMADAVAWGIGATAIWQLLRHGL
RNS

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 34979; Mature: 34848

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLWLWCALHLLIAALATWGLRRYALHRRLLDHPGERRSHTVATPRGGGMAIVAALLTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
CLVASFVWPTGRLSIAWFAAGLLLVAGVGWWDDHRPLSATLRFAIHALASVSLGLLVVRH
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
TGQPLDGILTALASVVLINVWNFMDGINGLASSQAALAGAAFALVVPGNLSWAGWALTAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
CLGFLPFNFPRARIFLGDGGSGALGYVLAGLLALSVGAGQVSWWIVWFPLTAFLVDAGFT
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLSRMLSGQRWWEPHASHVYQRLARLLTNHVPVTTVYFAFSLIAVCLFVIIRTDSRGWLM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ADAVAWGIGATAIWQLLRHGLRNS
HHHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPLWLWCALHLLIAALATWGLRRYALHRRLLDHPGERRSHTVATPRGGGMAIVAALLTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
CLVASFVWPTGRLSIAWFAAGLLLVAGVGWWDDHRPLSATLRFAIHALASVSLGLLVVRH
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
TGQPLDGILTALASVVLINVWNFMDGINGLASSQAALAGAAFALVVPGNLSWAGWALTAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
CLGFLPFNFPRARIFLGDGGSGALGYVLAGLLALSVGAGQVSWWIVWFPLTAFLVDAGFT
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LLSRMLSGQRWWEPHASHVYQRLARLLTNHVPVTTVYFAFSLIAVCLFVIIRTDSRGWLM
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ADAVAWGIGATAIWQLLRHGLRNS
HHHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]