Click here to switch to the map view.

The map label for this gene is ccmB [H]

Identifier: 66768218

GI number: 66768218

Start: 2292776

End: 2293471

Strand: Reverse

Name: ccmB [H]

Synonym: XC_1897

Alternate gene names: 66768218

Gene position: 2293471-2292776 (Counterclockwise)

Preceding gene: 66768219

Following gene: 66768217

Centisome position: 44.54

GC content: 68.53

Gene sequence:

>696_bases
ATGAGCGCGCATTCGCCGCAACCCTCGCTGTGGCAGGCCGGGCGGGCGCTGGTGCGCCGCGACCTGCAACTGCTGTGGCG
CCGCCGCAGCGATGCGCTGCAACCGGCGCTGTTTGCGCTGCTGATCGTGGTGCTGTTCGCGCTGGGCCTGGGCGGGCGCC
CGGACCTGTTGGCGCAGGCCGCGCCGGCGGTGCTGTGGCTGTCGGTGCTGCTGGCCGGGCTGTTGTCGCTGGATGCGCTG
TTCCGCAGCGATGTCGAAGACGGCTCGATGGAGCAATGGCTGCTCGCGCCGGTGCCGCTGGCCTGGTTGATCGCGGTGCG
CGTGCTGTTGCACTGGGCCACCAGCGCACTGCCGCTGATCGCGGTGACCCCGTTGCTGGGCGAATTGCTGCACCTGCCAC
ATGACCAACTGCCCGTGCTGCTGGCATCGTTGGCCCTGGGAACACCGCTTCTGAGCCTGCTCGGCGCCGTGGTTGCAGCG
CTGACAGTCACCATGAAACGCTCTGGTATTCTCGTGGCGCTGCTGGCGTTGCCGCTGTATGTGCCGGTGCTGGTGTTCGG
CGCCGGCAGTGTGGCAGCCAGCGGACAAGGCCAGGATGCGGTGGGTGCGTTGTTGTTGTTGGGGGCCGGCCTGGTGATCG
GCGTGGTTTTGGCACCGCTGGCTGCGGCGGCCGCGATCCGTATTTCACTGAGCTGA

Upstream 100 bases:

>100_bases
CCGCGCATCTGCGTGGCGGTGGCGCGGCCCTGGTCACCACGCACGGCGCCTATGCCGCGCCGCCGGTGCGCACGCGCATG
CTGACCCTGGAGGCCGCCGC

Downstream 100 bases:

>100_bases
CCAATGCAGTCGATGCGGCGTTGATGCGACACTCCGCTCCGCGAGCAATTGTCATACCGAGAGCCATCGCCATCGCATGA
ACGTCGTCGCCCGCTGGTTC

Product: ABC transporter heme permease

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSAHSPQPSLWQAGRALVRRDLQLLWRRRSDALQPALFALLIVVLFALGLGGRPDLLAQAAPAVLWLSVLLAGLLSLDAL
FRSDVEDGSMEQWLLAPVPLAWLIAVRVLLHWATSALPLIAVTPLLGELLHLPHDQLPVLLASLALGTPLLSLLGAVVAA
LTVTMKRSGILVALLALPLYVPVLVFGAGSVAASGQGQDAVGALLLLGAGLVIGVVLAPLAAAAAIRISLS

Sequences:

>Translated_231_residues
MSAHSPQPSLWQAGRALVRRDLQLLWRRRSDALQPALFALLIVVLFALGLGGRPDLLAQAAPAVLWLSVLLAGLLSLDAL
FRSDVEDGSMEQWLLAPVPLAWLIAVRVLLHWATSALPLIAVTPLLGELLHLPHDQLPVLLASLALGTPLLSLLGAVVAA
LTVTMKRSGILVALLALPLYVPVLVFGAGSVAASGQGQDAVGALLLLGAGLVIGVVLAPLAAAAAIRISLS
>Mature_230_residues
SAHSPQPSLWQAGRALVRRDLQLLWRRRSDALQPALFALLIVVLFALGLGGRPDLLAQAAPAVLWLSVLLAGLLSLDALF
RSDVEDGSMEQWLLAPVPLAWLIAVRVLLHWATSALPLIAVTPLLGELLHLPHDQLPVLLASLALGTPLLSLLGAVVAAL
TVTMKRSGILVALLALPLYVPVLVFGAGSVAASGQGQDAVGALLLLGAGLVIGVVLAPLAAAAAIRISLS

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=40, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23969; Mature: 23838

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHSPQPSLWQAGRALVRRDLQLLWRRRSDALQPALFALLIVVLFALGLGGRPDLLAQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
APAVLWLSVLLAGLLSLDALFRSDVEDGSMEQWLLAPVPLAWLIAVRVLLHWATSALPLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTPLLGELLHLPHDQLPVLLASLALGTPLLSLLGAVVAALTVTMKRSGILVALLALPLY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VPVLVFGAGSVAASGQGQDAVGALLLLGAGLVIGVVLAPLAAAAAIRISLS
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SAHSPQPSLWQAGRALVRRDLQLLWRRRSDALQPALFALLIVVLFALGLGGRPDLLAQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
APAVLWLSVLLAGLLSLDALFRSDVEDGSMEQWLLAPVPLAWLIAVRVLLHWATSALPLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTPLLGELLHLPHDQLPVLLASLALGTPLLSLLGAVVAALTVTMKRSGILVALLALPLY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VPVLVFGAGSVAASGQGQDAVGALLLLGAGLVIGVVLAPLAAAAAIRISLS
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]