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The map label for this gene is ykoW [H]

Identifier: 66768145

GI number: 66768145

Start: 2216864

End: 2218933

Strand: Reverse

Name: ykoW [H]

Synonym: XC_1824

Alternate gene names: 66768145

Gene position: 2218933-2216864 (Counterclockwise)

Preceding gene: 66768146

Following gene: 66768143

Centisome position: 43.1

GC content: 65.12

Gene sequence:

>2070_bases
ATGCAGAAAGGCAAAGATCTCACCCTCCGCCTGATGATTGTCGATGACAGCGTGGAGAGTGCCGAGGCCATCGTGACCGC
GCTGCGCAACGGCGGCATCGCCGTGCGGCCGTCACGCCCGCAGACACCGGAAGAGCTCGGCAGCATGTTGTCCGGGCAGA
TCGACCTGGCGGTGCAAGGCCAGGCGCAGCAGATTCCGATGTCGGCCCTGCAGCAGCAGATTGCCGGCAGCGGCAAGGAC
ATCCCGATCATCCAGCTGGCCGATCGCATCGAAGAGAACGCATTGGTCGAAGCCGCCGCGCATGGCGTGCGTGCGATTGC
GCTGCGCCATCGCACCGAGCATCTGCTGGCATTGGTGCGCTCTGAGTGGGCCGACCTGCAGGCGCGCCGCGGCTTGCGTC
GCATCGAGGCGCAGATGCGCGAAACCGAGCGCCGCTGCGATGCACTGATTGCCTCGTCGCGCGACCCGATCGCCTACGTC
CACGAAGGCATGCATATCCGTGCCAACGAGGCGTACCTGGAGATGTTCGGTTTTGAGTCCTTCGAGGACGTGGAAGGTGT
GTCGCTGCTGGACATGATCGCCGCGCAATACGTGGACGATTTCAAGCAACTGCTCAAGGCCCTGTCCAAGGGCGAGCCGC
CGCCGGCGCAGTACAAGGTCGACGCGCGTCGGCTGGAGGGCGATACCTTTCCGGCGACCATGGAATTTGCCACCGCCACC
TATGAGGGCGAGCCCTGCATCCAGGTGGTGTTCCGGCGCCGCGAAGAATTCGACCCGGAACTGGCGCGCGAGGTCGAGGA
CCTGCGCCAACGCGACCAGGTCACCGGCCTGCTCAACCGCCCCACCTTCATGGTGGCGCTCGAACAGGCGGTGGCACAGG
CCGGCCGCAGCGAAGGCCAGTCCGGCTTCCTGTTGATCGAACCGGATCATTACGCGCGGATCCTGCCGGAGATCGGCCTG
GATTCGGCGGATGCGCTGATCGCCTCACTGGCGGCGCACCTGGCCAGCGTGCTGGATGACAGCGTGGTGGCCGCGCGCTT
CGGCGAGCACAGCTTTGCGTTGTTGATGGACGGCAACTATGCGCGCTCGCATGCGCTGGCCGAATTGGTGCGTGACGCGT
TTGCGCAGCACGTGTTCAGTGTTGGCGAACGCTCGGCCACGGTCACCGTCAGCATCGGCGGTGTGCAGATTGGCGAGAAG
ATCGCCAGCATCGGGCAGGTGCTCAACCGCGGCACCGAGGCGGTGCGCACCACGGCCGAGCTCGGTGGCAATGCGGTCAG
CATCTTCGACCCGGCCGCCGCCGATCGCGCCGAGGAAGAACGCATCGAGCGCTGGGTGGAACAGTTGCGCGAGGCGCTGA
TCGGCGACGGCTTCCTGCTGCATTACCAGCCCGTGCTCAACCTGCAGGGCGAGCCGCTGGAGCTGTATCAGGCGTTCCTG
CGGCTGGAGCGCAATGGCGAGATGATGTCGCCGAATGCGTTCATGGCCATTGCCGAAGAACACGACCTGATCACCGAGAT
CGACCGCTGGGTGGTGGCACGTGCCATCCGCCAGCTGGGCGAGCGCCAGCGCGCCGGGCACAAGACCCACCTGCTGGTGC
GCATCGGGCCCAATTCGTTCTCCGACCCACAGATGATCGACACTATCCGCGAACAGCTGGCGGTCTACGGCGTGCCAGGA
GAGCGGTTGTGGCTGCAGACCCCGGAATCGAAGGTATTCACCCACCTGCGCAACGCCCAGCAATTCCTGGCTTCGGTCTC
GGCAATGGGCTGCAAGGTGGGGCTGGAGCAATTCGGTTCGGGACTGGATTCGTTCCAGCTGCTCGCACACTTCCAGCCCG
CGTTCCTCAAGCTCGACCGCAGCATCACCGGCGACATCGCCTCTGCCCGCGAAAGCCAGGAAAAGATCCGCGAGATCACC
TCACGGGCGCAGCCGACCGGCATCCTCACGGTGGCCGAGTTCGTGGCCGATGCACAGTCGATGAGCAGCTTCTTCACTGC
GGGGGTCGATTACGTGCAAGGCGACTTCGTCGCGCCCACCGGCCCGCTGATGAACTACGAGTTCGGCTGA

Upstream 100 bases:

>100_bases
GGAAGCGTGGCCTAGGTCTCACCGTCGCTGCGCGCCCGTCCACATACATGGACGCGCCGAACCCCTTCGTGTATTAAAGC
CCGTCTCTAGGGAGCCGCGC

Downstream 100 bases:

>100_bases
GGCCATAGCCACCCGCGTAAGGCGCCATGCTGCTGGCTGGCGCCGTGTGCGGTTTATCGCCACGGTGCGCTGCCGAGAAT
CAAGGAAACACGCCACAACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MQKGKDLTLRLMIVDDSVESAEAIVTALRNGGIAVRPSRPQTPEELGSMLSGQIDLAVQGQAQQIPMSALQQQIAGSGKD
IPIIQLADRIEENALVEAAAHGVRAIALRHRTEHLLALVRSEWADLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANEAYLEMFGFESFEDVEGVSLLDMIAAQYVDDFKQLLKALSKGEPPPAQYKVDARRLEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEIGL
DSADALIASLAAHLASVLDDSVVAARFGEHSFALLMDGNYARSHALAELVRDAFAQHVFSVGERSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIFDPAAADRAEEERIERWVEQLREALIGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLITEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLASVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRSITGDIASARESQEKIREIT
SRAQPTGILTVAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG

Sequences:

>Translated_689_residues
MQKGKDLTLRLMIVDDSVESAEAIVTALRNGGIAVRPSRPQTPEELGSMLSGQIDLAVQGQAQQIPMSALQQQIAGSGKD
IPIIQLADRIEENALVEAAAHGVRAIALRHRTEHLLALVRSEWADLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANEAYLEMFGFESFEDVEGVSLLDMIAAQYVDDFKQLLKALSKGEPPPAQYKVDARRLEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEIGL
DSADALIASLAAHLASVLDDSVVAARFGEHSFALLMDGNYARSHALAELVRDAFAQHVFSVGERSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIFDPAAADRAEEERIERWVEQLREALIGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLITEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLASVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRSITGDIASARESQEKIREIT
SRAQPTGILTVAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG
>Mature_689_residues
MQKGKDLTLRLMIVDDSVESAEAIVTALRNGGIAVRPSRPQTPEELGSMLSGQIDLAVQGQAQQIPMSALQQQIAGSGKD
IPIIQLADRIEENALVEAAAHGVRAIALRHRTEHLLALVRSEWADLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANEAYLEMFGFESFEDVEGVSLLDMIAAQYVDDFKQLLKALSKGEPPPAQYKVDARRLEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEIGL
DSADALIASLAAHLASVLDDSVVAARFGEHSFALLMDGNYARSHALAELVRDAFAQHVFSVGERSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIFDPAAADRAEEERIERWVEQLREALIGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLITEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLASVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRSITGDIASARESQEKIREIT
SRAQPTGILTVAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=25, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=26.8595041322314, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=23.6533957845433, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=23.728813559322, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788381, Length=432, Percent_Identity=22.6851851851852, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=22.6890756302521, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI226510982, Length=435, Percent_Identity=23.6781609195402, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081980, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789650, Length=279, Percent_Identity=22.9390681003584, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76027; Mature: 76027

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGKDLTLRLMIVDDSVESAEAIVTALRNGGIAVRPSRPQTPEELGSMLSGQIDLAVQG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCEEEEECC
QAQQIPMSALQQQIAGSGKDIPIIQLADRIEENALVEAAAHGVRAIALRHRTEHLLALVR
CHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEWADLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANEAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCHHHHHHHCCCC
FEDVEGVSLLDMIAAQYVDDFKQLLKALSKGEPPPAQYKVDARRLEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCHHHHHEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEIGLDSADALIASLAAHLASVLDDSVVAARFGEHSFALLMDGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
ARSHALAELVRDAFAQHVFSVGERSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAVSIFDPAAADRAEEERIERWVEQLREALIGDGFLLHYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLITEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLASVSAMGCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLDSFQLLAHFQPAFLKLDRSITGDIASARESQEKIREITSRAQPTGILTVAEFVADAQS
CCHHHHHHHHCCHHHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSSFFTAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKGKDLTLRLMIVDDSVESAEAIVTALRNGGIAVRPSRPQTPEELGSMLSGQIDLAVQG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCEEEEECC
QAQQIPMSALQQQIAGSGKDIPIIQLADRIEENALVEAAAHGVRAIALRHRTEHLLALVR
CHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEWADLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANEAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCHHHHHHHCCCC
FEDVEGVSLLDMIAAQYVDDFKQLLKALSKGEPPPAQYKVDARRLEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCHHHHHEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEIGLDSADALIASLAAHLASVLDDSVVAARFGEHSFALLMDGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
ARSHALAELVRDAFAQHVFSVGERSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAVSIFDPAAADRAEEERIERWVEQLREALIGDGFLLHYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLITEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLASVSAMGCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLDSFQLLAHFQPAFLKLDRSITGDIASARESQEKIREITSRAQPTGILTVAEFVADAQS
CCHHHHHHHHCCHHHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSSFFTAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]