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The map label for this gene is coaD [H]

Identifier: 66768046

GI number: 66768046

Start: 2082927

End: 2083433

Strand: Direct

Name: coaD [H]

Synonym: XC_1723

Alternate gene names: 66768046

Gene position: 2082927-2083433 (Clockwise)

Preceding gene: 66768045

Following gene: 66768047

Centisome position: 40.46

GC content: 64.89

Gene sequence:

>507_bases
ATGAGCGTGGCCAACAGCCGCACCGCTGTCTATCCCGGTACCTTCGACCCGATCACCAATGGCCATATCGACCTGGTGAA
CCGCGCCGCGCCGTTGTTCGAGCGTGTGGTTGTCGGCGTTGCCTACAGCCCGTCCAAGGGCCCGGCGCTGCCGTTGGAGC
GTCGCGTCGAACTCGCCCAGGAAGCCCTGGCGGCGCATGCCAATGTGGAAGTGCGCGGTTTCGATACCTTGCTGGCGCAT
TTCGTGCGCGACATGGGCGCCGGCGTGCTGCTGCGCGGCCTGCGTGCGGTGTCCGATTTCGAATACGAATTCCAGATGGC
CAGCATGAATCGCCATCTGATCCCGGAGGTGGAAACGCTGTTCCTCACCCCGGCCGAGCAGTACAGCTTCATCTCGTCTT
CGCTGGTGCGCGAAATCGCGCGGCTGGGCGGGGATGTGTCCGGCTTCGTTCCGGCGTCGGTCGTCGATGCCTTGCGCCAG
GTGCGTGAATCGCGCGCCCAGGTCTGA

Upstream 100 bases:

>100_bases
GGCACCTGCACCGTGAGGGCGCCACCCGTGAGGTGCGCTATGCGCTGTATCGCCGGGCCGCTGCTACACTGAACGGCGAT
CCGACCCCGGTAGCTTCCGT

Downstream 100 bases:

>100_bases
ACCGTCTTAGCAGTCAACACCACCACACGCTTTTCAAAGGGAGGAGTTTCATGAAACACACCATGCGCGCGCTGGCGCTC
GCTTCGATCGCCGCTCTGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQEALAAHANVEVRGFDTLLAH
FVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQ
VRESRAQV

Sequences:

>Translated_168_residues
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQEALAAHANVEVRGFDTLLAH
FVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQ
VRESRAQV
>Mature_167_residues
SVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQEALAAHANVEVRGFDTLLAHF
VRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQV
RESRAQV

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=152, Percent_Identity=59.8684210526316, Blast_Score=196, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18339; Mature: 18208

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQ
CCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
EALAAHANVEVRGFDTLLAHFVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHHHCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQVRESRAQV
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQ
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
EALAAHANVEVRGFDTLLAHFVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETL
HHHHHHCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHE
FLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQVRESRAQV
EECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]