Click here to switch to the map view.

The map label for this gene is ypdF [C]

Identifier: 66768027

GI number: 66768027

Start: 2043690

End: 2044889

Strand: Direct

Name: ypdF [C]

Synonym: XC_1703

Alternate gene names: 66768027

Gene position: 2043690-2044889 (Clockwise)

Preceding gene: 77761163

Following gene: 66768028

Centisome position: 39.69

GC content: 68.25

Gene sequence:

>1200_bases
ATGAGCACGCAGATCGGCGGGATGTCGCTGGACCAGGCCCGCACGCAGCTGGCGCCGTGGACGCAGCGGGCAGCGCCGAT
CGGCGCGGACGAATACCAGCAGCGTATCGAGCGCGCACGCGTGCTGATGCGCGCGCAGGGCGTGGATGCCTTGCTGATCG
GCGCAGGCACCTCGTTGCGCTATTTCAGCGGCGTGCCGTGGGGCGCCAGCGAGCGGCTGGTGGCGCTGTTGCTCACCACC
GAGGGCGACCCGGTGCTGATCTGCCCGGCCTTTGAAGAAGGCTCGCTGGATGCGGTGCTGCAACTCCCGGTGCGCAAGCG
CCTGTGGGAAGAGCACGAAGACCCGTATGCGCTGGTGGTGCAGGCCATGGATGAGCAGCATGCGCATGCCCTGGCGCTGG
ACCCGGGCATCGCCTTTGCGGTGCACACCGGTTTGCGGGCGCACCTGGGCACCGCGATCCGCGATGCCGGCGCCATCATC
GATGGCTGCCGCATGTGCAAGTCGCCGGCGGAGCTGGCGTTGATGCAGCAGGCCTGCGACATGACGCTGCTGGTGCAGCG
GCTGGCCGCCGGCATTGCGCACGAAGGTATCGGCACTGACCAACTGGTGCGCTTCATCGACGAAGCGCACCGCGCGCTGG
GTGCCGATAACGGCTCCACTTTTTGCATCGTGCAGTTTGGTCATGCCACCGCATTTCCGCATGGCATTCCCGGCGTGCAG
CATCTGCGGGCCGGCGAGCTGGTGTTGATCGATACCGGCTGCACCGTGCAGGGCTACCACTCCGACATTACCCGCACCTG
GATCTACGGCACGCCGAGCGACGCGCAGCAGCGCATCTGGGAACTGGAGCTGGCCGCGCAGGCGGCCGCGTTTGCCGCGG
TGCGCCCGGGCGTGGCGTGCGAGGCGGTTGACCAGGCGGCGCGCGCGGTGTTGCAGGCGGCCGGGTTGGGGCCGGATTAC
CGCTTGCCCGGGTTGCCGCACCGCACCGGCCATGGCTGCGGCCTGGCGATCCACGAAGCGCCGTACCTGGTGCGCGGCAA
TCGCCAGCCATTGCAGCCGGGCATGTGCGCCAGCAACGAACCAATGATCGTGGTGCCGGGTGCGTTCGGTGTGCGCCTGG
AAGACCATTTCTATGTCACCGACACCGGCGCGCAGTGGTTCACGCCGCCGTCGGTGGCGATCGATCAACCGTTTGCATGA

Upstream 100 bases:

>100_bases
CGGATGCGCTGCTGCCGATGGAGCTGCGCCAGCGCAACCCGGGCGGTGTGGCACGCCTGGTGGATGGGCAGTGGAGCAGC
GCCGACCTCGGGGCGCATGC

Downstream 100 bases:

>100_bases
GCCAGCACACGCGCGCAGTGCGCTGGTGTGGTGACCGGCATGGTCCGGTCGATCTCGTAGGAGCGCGCTTGCGCGCGATG
CGGCATTCCCGGGACAGCGT

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSTQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTT
EGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAII
DGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQ
HLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDY
RLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA

Sequences:

>Translated_399_residues
MSTQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTT
EGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAII
DGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQ
HLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDY
RLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
>Mature_398_residues
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTE
GDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIID
GCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQH
LRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYR
LPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI264681563, Length=140, Percent_Identity=35.7142857142857, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788728, Length=230, Percent_Identity=36.5217391304348, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789275, Length=257, Percent_Identity=27.6264591439689, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786364, Length=210, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920384, Length=259, Percent_Identity=27.7992277992278, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 42805; Mature: 42674

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLR
CCCCCCCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
YFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVV
HHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEECHHHHHHHHHCCCCCEEHE
QAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACD
EHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
MTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHH
HLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVAC
HCCCCCEEEEECCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCC
PMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
CEEEECCCCCEEEECEEEEEECCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLR
CCCCCCCCHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
YFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVV
HHCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEECHHHHHHHHHCCCCCEEHE
QAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACD
EHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
MTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHH
HLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVAC
HCCCCCEEEEECCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCC
PMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
CEEEECCCCCEEEECEEEEEECCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA