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The map label for this gene is nuoN [H]

Identifier: 66767926

GI number: 66767926

Start: 1921884

End: 1923344

Strand: Direct

Name: nuoN [H]

Synonym: XC_1602

Alternate gene names: 66767926

Gene position: 1921884-1923344 (Clockwise)

Preceding gene: 66767925

Following gene: 66767927

Centisome position: 37.33

GC content: 64.54

Gene sequence:

>1461_bases
ATGACCACGCCAACGCTCGCGCCGTTGACCACCGCTGACCTGGCTCCGCTCGCACCGGAGCTGGTGCTGATCGGCGGTGC
CTTCGCACTGTTGATGATCGATCTGTTCGTGAGCCAGCGGCACAAGGTCTGGACCCACCTGTTCTCTGTCGCAGTCCTGG
CCGTGGTGCTGGTGATGCTGGCAACCGGCACGGGCGGGCAGGGCGAAGCCTTCCACGGCATGTTCGTGCGCGACACCGCC
GCCGATGTCATGAAGACGGTGATCGTGCTGGTCAGTGGCCTGAGCCTGGTTTACGGCTGGAGCTATCTGCGCGAGCGCAA
TCTGTACCAGGGCGAGATTCCGGTGCTGGTGCTGTTTGCGACTGCCGGCATGATGCTGCTCACCTCCGCCGGCAGCCTGC
TGATGGTCTACCTTGGCCTGGAGTTGCTGGCGCTGTGCTCGTATGCGCTGGTGGCGTCCAACCGGGACAACGGCCTGGCG
ACCGAAGCGGCGATGAAGTACTTCGTGCTGGGTTCGCTGGCCTCCGGTCTGCTGTTGTACGGCATGTCGCTGGTGTATGG
CGCCACGGGGACGCTGAGCCTGGCCGGCATCCACGACGCAATCGAAGGCTCGGGCGAGCGCACGCTGTTGCTGACCGGTA
CGATCTTCATGATCGCCGGTGTGGCCTTCAAACTGGGTGCCGCGCCGTTCCATATGTGGCTGCCCGACGTCTATCAGGGT
GCGCCAGCGCCGATCGCGCTGTTCATCAGCTCCGCGCCCAAGCTGGCCGCCTTCGGCATGGCGTATCGCCTGCTCGAAAT
GGGCATGGGCCCGCTGTCGCCGCAGTGGCATCTGCTGATCGGTGGCCTGTCAGCTTTGTCGCTGGTGATCGGTAACCTGA
TGGCCATCGCGCAGAGCAACCTCAAGCGCATGCTGGCGTACTCAACGGTCTCGCATATCGGCTTCCTGCTGATGGGCGTG
GCAGGTGGCGGCGAGGAGGGCTATGCCGCCGCGATGTTCTACGCGGTGAGCTACACCATCATGTCCACGGCGTCGTTCGG
CGCGATCATTGCGCTGTCGCGCAGCGGCTTCGAAGCTGAGCACATCGACGACTTCAAGGGCCTGAACGCACGCAACCCGT
GGATGGCTGGCCTGGTGCTCTGCATCATGGCGTCGTTGGCCGGCATTCCGCCGTTCCTCGGTTTCTGGACCAAGCTGGCC
GTGCTCGGCGCGGCGGTGAAGGGCGACATGTTGTGGCTCGCGATGGTCGGCGTGCTGTGCGCGGTGATCGGTGCGTATTA
CTACCTGCGCGTCATCAAGGTCATGTACTTCGACGAACCGGTTGGCGAGCCGCTGCCTGCCAACAAGGATCGCGTGCTGG
GGACGGTGCTGGGTGTCAATGCGCTCGCGTTGCTCGCACTGGGCCTGGCCTGGAACCCGATCATGGTGTGGTGCCAGCGC
GCGTTTGCGGGCCTGGCCTGA

Upstream 100 bases:

>100_bases
GACCGACCTGATGGAACCGTCGATCGCCAAGCTGGCGACCCAGATTGCAACGACCAAGCTCTAACCGCTTGCCGTCCGTA
TTGATTTTCAGGATTTGATG

Downstream 100 bases:

>100_bases
TCGCATAGCTAGTGCCCGCTGTGTGCAGGCACGTGTCCTGACTAAACTGGCAGGGCACTGAAATAAAGTCGTGATCGCTG
TTTCGTTTTTGTGTCATCGC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTTPTLAPLTTADLAPLAPELVLIGGAFALLMIDLFVSQRHKVWTHLFSVAVLAVVLVMLATGTGGQGEAFHGMFVRDTA
ADVMKTVIVLVSGLSLVYGWSYLRERNLYQGEIPVLVLFATAGMMLLTSAGSLLMVYLGLELLALCSYALVASNRDNGLA
TEAAMKYFVLGSLASGLLLYGMSLVYGATGTLSLAGIHDAIEGSGERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQG
APAPIALFISSAPKLAAFGMAYRLLEMGMGPLSPQWHLLIGGLSALSLVIGNLMAIAQSNLKRMLAYSTVSHIGFLLMGV
AGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRSGFEAEHIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLA
VLGAAVKGDMLWLAMVGVLCAVIGAYYYLRVIKVMYFDEPVGEPLPANKDRVLGTVLGVNALALLALGLAWNPIMVWCQR
AFAGLA

Sequences:

>Translated_486_residues
MTTPTLAPLTTADLAPLAPELVLIGGAFALLMIDLFVSQRHKVWTHLFSVAVLAVVLVMLATGTGGQGEAFHGMFVRDTA
ADVMKTVIVLVSGLSLVYGWSYLRERNLYQGEIPVLVLFATAGMMLLTSAGSLLMVYLGLELLALCSYALVASNRDNGLA
TEAAMKYFVLGSLASGLLLYGMSLVYGATGTLSLAGIHDAIEGSGERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQG
APAPIALFISSAPKLAAFGMAYRLLEMGMGPLSPQWHLLIGGLSALSLVIGNLMAIAQSNLKRMLAYSTVSHIGFLLMGV
AGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRSGFEAEHIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLA
VLGAAVKGDMLWLAMVGVLCAVIGAYYYLRVIKVMYFDEPVGEPLPANKDRVLGTVLGVNALALLALGLAWNPIMVWCQR
AFAGLA
>Mature_485_residues
TTPTLAPLTTADLAPLAPELVLIGGAFALLMIDLFVSQRHKVWTHLFSVAVLAVVLVMLATGTGGQGEAFHGMFVRDTAA
DVMKTVIVLVSGLSLVYGWSYLRERNLYQGEIPVLVLFATAGMMLLTSAGSLLMVYLGLELLALCSYALVASNRDNGLAT
EAAMKYFVLGSLASGLLLYGMSLVYGATGTLSLAGIHDAIEGSGERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQGA
PAPIALFISSAPKLAAFGMAYRLLEMGMGPLSPQWHLLIGGLSALSLVIGNLMAIAQSNLKRMLAYSTVSHIGFLLMGVA
GGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRSGFEAEHIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLAV
LGAAVKGDMLWLAMVGVLCAVIGAYYYLRVIKVMYFDEPVGEPLPANKDRVLGTVLGVNALALLALGLAWNPIMVWCQRA
FAGLA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=319, Percent_Identity=25.3918495297806, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI145693160, Length=475, Percent_Identity=33.4736842105263, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1788614, Length=368, Percent_Identity=27.445652173913, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788827, Length=324, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788831, Length=332, Percent_Identity=25.9036144578313, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788613, Length=333, Percent_Identity=27.027027027027, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788829, Length=347, Percent_Identity=25.9365994236311, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51356; Mature: 51225

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTLAPLTTADLAPLAPELVLIGGAFALLMIDLFVSQRHKVWTHLFSVAVLAVVLVML
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGTGGQGEAFHGMFVRDTAADVMKTVIVLVSGLSLVYGWSYLRERNLYQGEIPVLVLFA
HCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
TAGMMLLTSAGSLLMVYLGLELLALCSYALVASNRDNGLATEAAMKYFVLGSLASGLLLY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GMSLVYGATGTLSLAGIHDAIEGSGERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQG
HHHHHHCCCCCEEEHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCHHHCC
APAPIALFISSAPKLAAFGMAYRLLEMGMGPLSPQWHLLIGGLSALSLVIGNLMAIAQSN
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKRMLAYSTVSHIGFLLMGVAGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRSGFEAE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
HIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLAVLGAAVKGDMLWLAMVGVLC
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIGAYYYLRVIKVMYFDEPVGEPLPANKDRVLGTVLGVNALALLALGLAWNPIMVWCQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AFAGLA
HHHCCC
>Mature Secondary Structure 
TTPTLAPLTTADLAPLAPELVLIGGAFALLMIDLFVSQRHKVWTHLFSVAVLAVVLVML
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGTGGQGEAFHGMFVRDTAADVMKTVIVLVSGLSLVYGWSYLRERNLYQGEIPVLVLFA
HCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHH
TAGMMLLTSAGSLLMVYLGLELLALCSYALVASNRDNGLATEAAMKYFVLGSLASGLLLY
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GMSLVYGATGTLSLAGIHDAIEGSGERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQG
HHHHHHCCCCCEEEHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHHHCCHHHCC
APAPIALFISSAPKLAAFGMAYRLLEMGMGPLSPQWHLLIGGLSALSLVIGNLMAIAQSN
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKRMLAYSTVSHIGFLLMGVAGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRSGFEAE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
HIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLAVLGAAVKGDMLWLAMVGVLC
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIGAYYYLRVIKVMYFDEPVGEPLPANKDRVLGTVLGVNALALLALGLAWNPIMVWCQR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AFAGLA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA