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The map label for this gene is aspA [H]

Identifier: 66767768

GI number: 66767768

Start: 1739184

End: 1740887

Strand: Reverse

Name: aspA [H]

Synonym: XC_1442

Alternate gene names: 66767768

Gene position: 1740887-1739184 (Counterclockwise)

Preceding gene: 66767769

Following gene: 66767767

Centisome position: 33.81

GC content: 62.32

Gene sequence:

>1704_bases
GTGTTGGCGCAAACCCCGGCAACATCACGCGCCCAACCCAGGCCACCAGAAGAAAGTGACCCGCTTTTCCGCTATCAATG
GCATTTGCTCAACGATGGGCAAGAGGTCATTGCCGACACTCGGCCACGCGCCGGAACGGATCTGAATGTGGGCCCGCTGC
ATACGTTGGGGCTGCGTGGACAAGGCGTAACCGTCGCCGTCGTGGACGACGCACTCGAACTACGCCACCCGGATCTTGTT
GCCAACGTGGTGCCCGGCGGTTCCAAGAACTTTGTCGATGGATCGAATGATCCAACGCCACGCAACGGCGCTTCCCACGG
CACGATGGTTGGCGGGATCATGGCGGCAGTGGGCTGGAACGGGCTTGGTGGTCGCGGCGTTGCGCCCGATGCGCGCCTGA
AAGGTTTCAACATCCTTTCCTCAGAAGAAAGCCCGACCGACTTCGATACCAATCTACGCGCCTCCTGGGGCGATTCGGTG
CAATCCCGGGATGTGGATGTATTCAATAACAGCTTTGGCTCAGATCTGACGTACTACCCGACAATCTCTCCAGCAGCAGA
GCGCTCGCTTGACCGCTTGATGCGTCGAGCAAGAAACGGCAAGGGGGGTCTGTATGTCCAGGCAGCAGGGAACACGTTCG
ATAGTTTTACGGTTCTCGACGACCAGGGGAACTGGGTGGAGCGATGCCCTGTGCTGGCCCGCACCTTGGGAGTCACTTGC
TCCACGCCGGCTACCGATCCGTTGAGTAACCAACCCCTGATCATCGCGACGGGCGCAGTCAATGCACGCGGCCTGCGCTC
GTCCTACTCTTCAGCCGGCGCGGCGCTATGGGTCACCGGCTTCGGCGGGGAGTTCGGGCTGCAACGCCGCTACTTTGGCG
ACCGGCCGCGGCCCGCGTTGTTCGATCCCGCCATCGTCACCACCGACCTGACTGGCTGCGCCGTCGGTGACAACAGGGAC
ATCGCCGGCCAGCCGCCGATCAATGCATTGGCTTCAAGCAGCTCACCGATCGACGCCTCTTGCAACTACTCCGCGGCAAT
GAACGGCACCTCCGCAGCGGCACCCACGGTTGCTGGGGTGGTTGCGCTGATCGTGCAGGCCAATCCGTCGCTCACCGCGC
GCGACCTTAAGTACATCCTGGCAACAAGCGCGCGCCAGATCGATCCTGCGCAGCAGGTGATCCGCTACCAAGGCAGCGTG
ATCGAGCCGGGCTGGATCACCAATGCGGCCGGCCATGCATTTAGCAACTGGTACGGTTTCGGCCTGGTGGACGCTGCCGA
AGCGGTCTATCGCGCCTATGGGTTCCAGCCGCTTCCGCCCCAGCGCGATCTGGGCTGGAAAGCGGCACGCGCAGGCACAT
CGACGATTGGCGGACCAAATGCCGCGGCAACCTTGCGGTTGCGGCTCGGGGACACGCTCAAGATCGACACCGTGCAGTGG
TCGATGCAGACCACCCACAAGACACCGAGCAATCTCCGGGTAGTGCTGATCTCGCCGAGTGGCACCCGCAGCTACGTGCT
CACTCCCTTCCAGGCCTTGGATACGATCACGCAGGGGGCCGGCTTTGAGATACCGCTTTCGACCAGCAATGCCTTCCTAG
ACGAAAACGTTGCCGGCACCTGGACGCTGGAAGTCACCGACATGACCGGCTCGGACGTTCCCGCCCAACTGACGGGCTTC
AAACTGCGCATCCGGGGACATTGA

Upstream 100 bases:

>100_bases
CACCCAAATGGGACTCTGTTGATGACTTCTTTTCCGCAACGGCAATTGCTGTTCTCCGCGCTCGTGCTGGCGCTGTGTAG
CGCGGCATCCTCGGCACCGG

Downstream 100 bases:

>100_bases
CATGAACCTCGCTCTCGGTACGACCCTCATCCTTTGCGCGCTTGCCAGCATGCCGGCCTCTGCGCAAGACACCGACCGGC
TCGCATTGCAGCGTGCCGCA

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MLAQTPATSRAQPRPPEESDPLFRYQWHLLNDGQEVIADTRPRAGTDLNVGPLHTLGLRGQGVTVAVVDDALELRHPDLV
ANVVPGGSKNFVDGSNDPTPRNGASHGTMVGGIMAAVGWNGLGGRGVAPDARLKGFNILSSEESPTDFDTNLRASWGDSV
QSRDVDVFNNSFGSDLTYYPTISPAAERSLDRLMRRARNGKGGLYVQAAGNTFDSFTVLDDQGNWVERCPVLARTLGVTC
STPATDPLSNQPLIIATGAVNARGLRSSYSSAGAALWVTGFGGEFGLQRRYFGDRPRPALFDPAIVTTDLTGCAVGDNRD
IAGQPPINALASSSSPIDASCNYSAAMNGTSAAAPTVAGVVALIVQANPSLTARDLKYILATSARQIDPAQQVIRYQGSV
IEPGWITNAAGHAFSNWYGFGLVDAAEAVYRAYGFQPLPPQRDLGWKAARAGTSTIGGPNAAATLRLRLGDTLKIDTVQW
SMQTTHKTPSNLRVVLISPSGTRSYVLTPFQALDTITQGAGFEIPLSTSNAFLDENVAGTWTLEVTDMTGSDVPAQLTGF
KLRIRGH

Sequences:

>Translated_567_residues
MLAQTPATSRAQPRPPEESDPLFRYQWHLLNDGQEVIADTRPRAGTDLNVGPLHTLGLRGQGVTVAVVDDALELRHPDLV
ANVVPGGSKNFVDGSNDPTPRNGASHGTMVGGIMAAVGWNGLGGRGVAPDARLKGFNILSSEESPTDFDTNLRASWGDSV
QSRDVDVFNNSFGSDLTYYPTISPAAERSLDRLMRRARNGKGGLYVQAAGNTFDSFTVLDDQGNWVERCPVLARTLGVTC
STPATDPLSNQPLIIATGAVNARGLRSSYSSAGAALWVTGFGGEFGLQRRYFGDRPRPALFDPAIVTTDLTGCAVGDNRD
IAGQPPINALASSSSPIDASCNYSAAMNGTSAAAPTVAGVVALIVQANPSLTARDLKYILATSARQIDPAQQVIRYQGSV
IEPGWITNAAGHAFSNWYGFGLVDAAEAVYRAYGFQPLPPQRDLGWKAARAGTSTIGGPNAAATLRLRLGDTLKIDTVQW
SMQTTHKTPSNLRVVLISPSGTRSYVLTPFQALDTITQGAGFEIPLSTSNAFLDENVAGTWTLEVTDMTGSDVPAQLTGF
KLRIRGH
>Mature_567_residues
MLAQTPATSRAQPRPPEESDPLFRYQWHLLNDGQEVIADTRPRAGTDLNVGPLHTLGLRGQGVTVAVVDDALELRHPDLV
ANVVPGGSKNFVDGSNDPTPRNGASHGTMVGGIMAAVGWNGLGGRGVAPDARLKGFNILSSEESPTDFDTNLRASWGDSV
QSRDVDVFNNSFGSDLTYYPTISPAAERSLDRLMRRARNGKGGLYVQAAGNTFDSFTVLDDQGNWVERCPVLARTLGVTC
STPATDPLSNQPLIIATGAVNARGLRSSYSSAGAALWVTGFGGEFGLQRRYFGDRPRPALFDPAIVTTDLTGCAVGDNRD
IAGQPPINALASSSSPIDASCNYSAAMNGTSAAAPTVAGVVALIVQANPSLTARDLKYILATSARQIDPAQQVIRYQGSV
IEPGWITNAAGHAFSNWYGFGLVDAAEAVYRAYGFQPLPPQRDLGWKAARAGTSTIGGPNAAATLRLRLGDTLKIDTVQW
SMQTTHKTPSNLRVVLISPSGTRSYVLTPFQALDTITQGAGFEIPLSTSNAFLDENVAGTWTLEVTDMTGSDVPAQLTGF
KLRIRGH

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI76443679, Length=536, Percent_Identity=27.6119402985075, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI20336180, Length=552, Percent_Identity=24.6376811594203, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI4505577, Length=553, Percent_Identity=24.9547920433996, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI20336182, Length=552, Percent_Identity=24.6376811594203, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI20336190, Length=557, Percent_Identity=24.5960502692998, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI20336188, Length=553, Percent_Identity=24.9547920433996, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI27894285, Length=557, Percent_Identity=24.5960502692998, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI20336184, Length=552, Percent_Identity=24.6376811594203, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI299523015, Length=557, Percent_Identity=25.673249551167, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI20336246, Length=556, Percent_Identity=25.5395683453237, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI20336242, Length=575, Percent_Identity=25.5652173913043, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI295424143, Length=575, Percent_Identity=25.5652173913043, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI20336248, Length=558, Percent_Identity=25.9856630824373, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI20336186, Length=422, Percent_Identity=24.1706161137441, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4505579, Length=208, Percent_Identity=32.6923076923077, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI20336244, Length=202, Percent_Identity=34.1584158415842, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI295424145, Length=248, Percent_Identity=28.2258064516129, Blast_Score=73, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71988321, Length=567, Percent_Identity=26.8077601410935, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988301, Length=567, Percent_Identity=26.8077601410935, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988297, Length=562, Percent_Identity=26.8683274021352, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988312, Length=562, Percent_Identity=26.5124555160142, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71988308, Length=562, Percent_Identity=26.5124555160142, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71988315, Length=567, Percent_Identity=26.4550264550265, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25141268, Length=571, Percent_Identity=26.7950963222417, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71983555, Length=436, Percent_Identity=26.1467889908257, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71987206, Length=210, Percent_Identity=31.4285714285714, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324091, Length=542, Percent_Identity=25.830258302583, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24642488, Length=543, Percent_Identity=25.9668508287293, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24642484, Length=543, Percent_Identity=25.9668508287293, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24642486, Length=543, Percent_Identity=25.9668508287293, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24642494, Length=543, Percent_Identity=26.1510128913444, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24642490, Length=543, Percent_Identity=26.1510128913444, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45555723, Length=543, Percent_Identity=26.1510128913444, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24642492, Length=543, Percent_Identity=26.1510128913444, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360987, Length=543, Percent_Identity=26.1510128913444, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17864552, Length=514, Percent_Identity=25.0972762645914, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI45553515, Length=514, Percent_Identity=25.4863813229572, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24650056, Length=513, Percent_Identity=24.7563352826511, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24650058, Length=515, Percent_Identity=24.6601941747573, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650060, Length=515, Percent_Identity=24.6601941747573, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45553513, Length=515, Percent_Identity=24.6601941747573, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360985, Length=196, Percent_Identity=32.6530612244898, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136192, Length=212, Percent_Identity=31.6037735849057, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 60113; Mature: 60113

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQTPATSRAQPRPPEESDPLFRYQWHLLNDGQEVIADTRPRAGTDLNVGPLHTLGLRG
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCEEECCCC
QGVTVAVVDDALELRHPDLVANVVPGGSKNFVDGSNDPTPRNGASHGTMVGGIMAAVGWN
CCEEEEEECCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GLGGRGVAPDARLKGFNILSSEESPTDFDTNLRASWGDSVQSRDVDVFNNSFGSDLTYYP
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEC
TISPAAERSLDRLMRRARNGKGGLYVQAAGNTFDSFTVLDDQGNWVERCPVLARTLGVTC
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCEE
STPATDPLSNQPLIIATGAVNARGLRSSYSSAGAALWVTGFGGEFGLQRRYFGDRPRPAL
CCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCCCC
FDPAIVTTDLTGCAVGDNRDIAGQPPINALASSSSPIDASCNYSAAMNGTSAAAPTVAGV
CCCEEEEECCCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHH
VALIVQANPSLTARDLKYILATSARQIDPAQQVIRYQGSVIEPGWITNAAGHAFSNWYGF
HEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCHHHCCCCC
GLVDAAEAVYRAYGFQPLPPQRDLGWKAARAGTSTIGGPNAAATLRLRLGDTLKIDTVQW
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCEEEEEEEEE
SMQTTHKTPSNLRVVLISPSGTRSYVLTPFQALDTITQGAGFEIPLSTSNAFLDENVAGT
EEECCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHCCCCEEEEECCCCCEECCCCCEE
WTLEVTDMTGSDVPAQLTGFKLRIRGH
EEEEEEECCCCCCCCEECCEEEEEECC
>Mature Secondary Structure
MLAQTPATSRAQPRPPEESDPLFRYQWHLLNDGQEVIADTRPRAGTDLNVGPLHTLGLRG
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCEEECCCC
QGVTVAVVDDALELRHPDLVANVVPGGSKNFVDGSNDPTPRNGASHGTMVGGIMAAVGWN
CCEEEEEECCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GLGGRGVAPDARLKGFNILSSEESPTDFDTNLRASWGDSVQSRDVDVFNNSFGSDLTYYP
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEC
TISPAAERSLDRLMRRARNGKGGLYVQAAGNTFDSFTVLDDQGNWVERCPVLARTLGVTC
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCEE
STPATDPLSNQPLIIATGAVNARGLRSSYSSAGAALWVTGFGGEFGLQRRYFGDRPRPAL
CCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCCCCCCC
FDPAIVTTDLTGCAVGDNRDIAGQPPINALASSSSPIDASCNYSAAMNGTSAAAPTVAGV
CCCEEEEECCCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHH
VALIVQANPSLTARDLKYILATSARQIDPAQQVIRYQGSVIEPGWITNAAGHAFSNWYGF
HEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCHHHCCCCC
GLVDAAEAVYRAYGFQPLPPQRDLGWKAARAGTSTIGGPNAAATLRLRLGDTLKIDTVQW
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEEEECCEEEEEEEEE
SMQTTHKTPSNLRVVLISPSGTRSYVLTPFQALDTITQGAGFEIPLSTSNAFLDENVAGT
EEECCCCCCCCCEEEEECCCCCCCEEECCHHHHHHHHCCCCEEEEECCCCCEECCCCCEE
WTLEVTDMTGSDVPAQLTGFKLRIRGH
EEEEEEECCCCCCCCEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]