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The map label for this gene is 66767548

Identifier: 66767548

GI number: 66767548

Start: 1491817

End: 1493502

Strand: Reverse

Name: 66767548

Synonym: XC_1221

Alternate gene names: NA

Gene position: 1493502-1491817 (Counterclockwise)

Preceding gene: 66767549

Following gene: 66767547

Centisome position: 29.01

GC content: 65.36

Gene sequence:

>1686_bases
ATGACGACCGATAGCCGCCTTGCGGCTCCATCCCGCCGCCACGCCGGAGCTGCACCCAGAACGCGAATGCTCGCGCTCGG
TCTGTTGCTCGCGTTGCCTGCCGCCACGCTCAGCGCTGCGCAATCGCCCACCGCGCCGACCGCCACCACGCTCAGCCCCG
AGGTCATCGACCAGCAGTGGCTCGACGCCACCGCGCAGTACGCGCCCGAACGCGCACGGCTGGTGCGCGAAGCGCAAGCC
GGCGCGCGCAAGGGGCCGTTCCGCCCTGACTGGGCCGCATTGAAGGCGTATCAATCGCCTGCGTGGTACGACAACGCCAA
GTTCGGCATCTTCATTCACTGGGGCGTGTTTTCGGTGCCGGCCTTCGGCAGCGAATGGTATTCGCGCAACATGTATCTGG
AAGGCTCCAAGGAATTCGCGCACCACGTGGCGACCTATGGCCCGCAGGCCAGCAGCGGCTACAAGGACCTGATTCCCAAG
TTCACCGCACCCAAGTTCGACCCCACTGGCTGGGCCAAGCTGTTCCGTGAATCCGGTGCGCGCTACGTGGTGCCGGTGGC
CGAGCATCACGATGGCTTTGCGTTGTACGACTCGAAGTTGTCCGATTGGACGGCGATGAAGATGGGGCCCAAGCGCGACC
TGCTGGGCGAGTTGTCCACCGCGATCCGTGCGCAGGGCCTGCACTTCGGGCTGTCCTCTCACCGCGCCGAGCACAACTGG
TTCTTCGATGGCGGGCGCAAGTTCGATTCGGACGTCAACGACCCGCGCTATGCGGCTCTGTATGGCCCCGCGCAGGTGCG
CCTGCCCGGCAAGGACGACGCCGACGTCGCCAACGACTGGACGCCGGTGTCGCAGGCGTGGCTGGACGACTGGCTGGCGC
GCACCACCGAGTTGATCGATGTCTACCAGCCGGACCTGATCTATTTCGATTGGTGGATCGCCCATCCCACCTTCCGCAGC
AGCCTGCCGACCATGCTGGCGTACTACTACAACCAGGGCGCGGCGCGGACCGAAGCCGACCGTGGCGTGGTGGTGAACTA
CAAGCTGGGTGCGTTCCCCGAAGGCGCCGGCACGCTGGATATCGAGCGCGGCCAGCTCACCGGCATCCACCCCACGCATT
GGCAGACCGACACCTCGGTGAGCAATGCGTCGTGGGGCTACATCGAAAACGACACCTACAAGTCGCCCACCTTCATCATC
CACATGCTGGCCGATGTGGTGGCCAAGAACGGCAACCTGATGCTCAACATCGGCCCGCGCGCCGATGGCTCCATCCCCGA
CACCGAGCGCGGCATCCTGCTTTCGATCGGCAAGTGGCTCAAGACCAATGGCGGCGCGATCTACGACAGCAAGCCGTGGC
GCGTGTATGGCGAAGGCCCCACCGAAGTGGTGGGCGGCACCTTCCAGGACGTCAAGACCAAGCCGTACACGGCTGAAGAT
TTCCGCTTCACCACCCGCGATGGCGCGCTATATGCCATCGAACTGGGCTGGCCGGCCGATGGCAAGGCGGTGATCCGCTC
GCTCACCGCCGCCGATGGCGTGCGCGGGGTGACGCTGCTGGCCAATGGCAAAAAGGTTCCCTTCGAACAACAGGCCGATG
GCTTGCACCTGCGGCTGCCGGCCAAGCCGGTCGGCGAAAGCGCCTACGTGTTCCGCATCGACCTTGCGCCCTCTTCCACT
CCCTGA

Upstream 100 bases:

>100_bases
CCATCGCCCTTCGCTGAAGGATGATGGCCAGTCCCGCTTCCGCAACCACGGGCCGGATGCCTGATGCCGGTGCGTCTTTG
CCCACAGGAGTGCAGTTCCC

Downstream 100 bases:

>100_bases
CGGATCCTGTCTTCATGATCAAGCGATTGACCTGGATGTTGCTCGCGCTGGCGGTTGCCTGCGCGCCCACCTTGGCGCTG
GCCAAGAACCCTACGGCGCT

Product: alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Exported Alpha-L-Fucosidase Protein; Fucosidase; Alpha-L-Fucosidase Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Family; Exporte Hydrolase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase Superfamily; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; Glycoside Hydrolase

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTTDSRLAAPSRRHAGAAPRTRMLALGLLLALPAATLSAAQSPTAPTATTLSPEVIDQQWLDATAQYAPERARLVREAQA
GARKGPFRPDWAALKAYQSPAWYDNAKFGIFIHWGVFSVPAFGSEWYSRNMYLEGSKEFAHHVATYGPQASSGYKDLIPK
FTAPKFDPTGWAKLFRESGARYVVPVAEHHDGFALYDSKLSDWTAMKMGPKRDLLGELSTAIRAQGLHFGLSSHRAEHNW
FFDGGRKFDSDVNDPRYAALYGPAQVRLPGKDDADVANDWTPVSQAWLDDWLARTTELIDVYQPDLIYFDWWIAHPTFRS
SLPTMLAYYYNQGAARTEADRGVVVNYKLGAFPEGAGTLDIERGQLTGIHPTHWQTDTSVSNASWGYIENDTYKSPTFII
HMLADVVAKNGNLMLNIGPRADGSIPDTERGILLSIGKWLKTNGGAIYDSKPWRVYGEGPTEVVGGTFQDVKTKPYTAED
FRFTTRDGALYAIELGWPADGKAVIRSLTAADGVRGVTLLANGKKVPFEQQADGLHLRLPAKPVGESAYVFRIDLAPSST
P

Sequences:

>Translated_561_residues
MTTDSRLAAPSRRHAGAAPRTRMLALGLLLALPAATLSAAQSPTAPTATTLSPEVIDQQWLDATAQYAPERARLVREAQA
GARKGPFRPDWAALKAYQSPAWYDNAKFGIFIHWGVFSVPAFGSEWYSRNMYLEGSKEFAHHVATYGPQASSGYKDLIPK
FTAPKFDPTGWAKLFRESGARYVVPVAEHHDGFALYDSKLSDWTAMKMGPKRDLLGELSTAIRAQGLHFGLSSHRAEHNW
FFDGGRKFDSDVNDPRYAALYGPAQVRLPGKDDADVANDWTPVSQAWLDDWLARTTELIDVYQPDLIYFDWWIAHPTFRS
SLPTMLAYYYNQGAARTEADRGVVVNYKLGAFPEGAGTLDIERGQLTGIHPTHWQTDTSVSNASWGYIENDTYKSPTFII
HMLADVVAKNGNLMLNIGPRADGSIPDTERGILLSIGKWLKTNGGAIYDSKPWRVYGEGPTEVVGGTFQDVKTKPYTAED
FRFTTRDGALYAIELGWPADGKAVIRSLTAADGVRGVTLLANGKKVPFEQQADGLHLRLPAKPVGESAYVFRIDLAPSST
P
>Mature_560_residues
TTDSRLAAPSRRHAGAAPRTRMLALGLLLALPAATLSAAQSPTAPTATTLSPEVIDQQWLDATAQYAPERARLVREAQAG
ARKGPFRPDWAALKAYQSPAWYDNAKFGIFIHWGVFSVPAFGSEWYSRNMYLEGSKEFAHHVATYGPQASSGYKDLIPKF
TAPKFDPTGWAKLFRESGARYVVPVAEHHDGFALYDSKLSDWTAMKMGPKRDLLGELSTAIRAQGLHFGLSSHRAEHNWF
FDGGRKFDSDVNDPRYAALYGPAQVRLPGKDDADVANDWTPVSQAWLDDWLARTTELIDVYQPDLIYFDWWIAHPTFRSS
LPTMLAYYYNQGAARTEADRGVVVNYKLGAFPEGAGTLDIERGQLTGIHPTHWQTDTSVSNASWGYIENDTYKSPTFIIH
MLADVVAKNGNLMLNIGPRADGSIPDTERGILLSIGKWLKTNGGAIYDSKPWRVYGEGPTEVVGGTFQDVKTKPYTAEDF
RFTTRDGALYAIELGWPADGKAVIRSLTAADGVRGVTLLANGKKVPFEQQADGLHLRLPAKPVGESAYVFRIDLAPSSTP

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI119360348, Length=478, Percent_Identity=34.1004184100418, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI40068512, Length=463, Percent_Identity=31.9654427645788, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71997700, Length=387, Percent_Identity=30.2325581395349, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24662717, Length=388, Percent_Identity=31.4432989690722, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI78706642, Length=388, Percent_Identity=31.4432989690722, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 61836; Mature: 61705

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDSRLAAPSRRHAGAAPRTRMLALGLLLALPAATLSAAQSPTAPTATTLSPEVIDQQW
CCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LDATAQYAPERARLVREAQAGARKGPFRPDWAALKAYQSPAWYDNAKFGIFIHWGVFSVP
HHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
AFGSEWYSRNMYLEGSKEFAHHVATYGPQASSGYKDLIPKFTAPKFDPTGWAKLFRESGA
CCCHHHHHCCEEEECCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCC
RYVVPVAEHHDGFALYDSKLSDWTAMKMGPKRDLLGELSTAIRAQGLHFGLSSHRAEHNW
EEEEEECCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEECHHHCCCCCCE
FFDGGRKFDSDVNDPRYAALYGPAQVRLPGKDDADVANDWTPVSQAWLDDWLARTTELID
EECCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VYQPDLIYFDWWIAHPTFRSSLPTMLAYYYNQGAARTEADRGVVVNYKLGAFPEGAGTLD
HCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IERGQLTGIHPTHWQTDTSVSNASWGYIENDTYKSPTFIIHMLADVVAKNGNLMLNIGPR
EECCEECCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
ADGSIPDTERGILLSIGKWLKTNGGAIYDSKPWRVYGEGPTEVVGGTFQDVKTKPYTAED
CCCCCCCCCCCEEEEECHHHHCCCCEEECCCCCEEECCCCHHHCCCCHHHCCCCCCCCCC
FRFTTRDGALYAIELGWPADGKAVIRSLTAADGVRGVTLLANGKKVPFEQQADGLHLRLP
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEECC
AKPVGESAYVFRIDLAPSSTP
CCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
TTDSRLAAPSRRHAGAAPRTRMLALGLLLALPAATLSAAQSPTAPTATTLSPEVIDQQW
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
LDATAQYAPERARLVREAQAGARKGPFRPDWAALKAYQSPAWYDNAKFGIFIHWGVFSVP
HHHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
AFGSEWYSRNMYLEGSKEFAHHVATYGPQASSGYKDLIPKFTAPKFDPTGWAKLFRESGA
CCCHHHHHCCEEEECCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCC
RYVVPVAEHHDGFALYDSKLSDWTAMKMGPKRDLLGELSTAIRAQGLHFGLSSHRAEHNW
EEEEEECCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEECHHHCCCCCCE
FFDGGRKFDSDVNDPRYAALYGPAQVRLPGKDDADVANDWTPVSQAWLDDWLARTTELID
EECCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VYQPDLIYFDWWIAHPTFRSSLPTMLAYYYNQGAARTEADRGVVVNYKLGAFPEGAGTLD
HCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IERGQLTGIHPTHWQTDTSVSNASWGYIENDTYKSPTFIIHMLADVVAKNGNLMLNIGPR
EECCEECCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCC
ADGSIPDTERGILLSIGKWLKTNGGAIYDSKPWRVYGEGPTEVVGGTFQDVKTKPYTAED
CCCCCCCCCCCEEEEECHHHHCCCCEEECCCCCEEECCCCHHHCCCCHHHCCCCCCCCCC
FRFTTRDGALYAIELGWPADGKAVIRSLTAADGVRGVTLLANGKKVPFEQQADGLHLRLP
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEECC
AKPVGESAYVFRIDLAPSSTP
CCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA