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The map label for this gene is nahA [H]

Identifier: 66767546

GI number: 66767546

Start: 1488135

End: 1490561

Strand: Reverse

Name: nahA [H]

Synonym: XC_1219

Alternate gene names: 66767546

Gene position: 1490561-1488135 (Counterclockwise)

Preceding gene: 66767547

Following gene: 66767545

Centisome position: 28.95

GC content: 67.78

Gene sequence:

>2427_bases
ATGATGTCGTCGCGACGGCTGCTGTCCACACGATTGCCGTCGCGCCTGCTTGTCTGCTGCGTTGCAGTCAGCGCCCTGCT
TGGATGTGGTCAACGCGAGGCCGGCACTGCACCGGCCGTTGCCAGTGCAGGCGCCCCCGCGGCACCTGCCGCCAACACAC
CGCTGCCCCTGATTCCGGCACCGGCGCAGGTCACACGCGGCAGTGGCAGTTTCCACATCGGTGCCGGCACGGTGATTTCG
ATCGTCGGTGGCGATGCCGATGCACGCCGCAGCGCCGAATATCTCGCCGAGCTGCTCAAGCGCACGCGCGGCCTGTCGCT
GGAAGTGCGCAACGAAACCAGCGCCTCACCGGGCAGCATCCGCCTGGAACGCAGCGCGCAGGCACCGGTAGCGCAGAAGG
AAGGCTATAGCCTGGATAGCGACGCGAAGGGCCTCCGCATCCAGGCGCGTGATGGCGCCGGGTTGTTCTACGGCACCGTG
AGCGCATGGCAGTTGATGACCCCGGATGCACGCAAGGGCGATGTCGAGGTACCGGCGGTGGCCATCCGCGACTGGCCGCG
TTTCAGCTGGCGCGGCCAGCATCTGGATGTGGCGCGCCACTTCCACGACGTGGCAACGGTCAAGCATGTGCTCGACACGA
TGGCCGTGCACAAGCTCAACGTGCTGCACTGGCATCTCACCGATGACCAGGGCTGGCGGATCGAGATCAAGCGCTACCCC
AAGCTCACCGAGGTGGGTGCGTGGCGCACGCCGCCGGGCGCGGGCCAGCACGGCACACCGGAGCGCTATGGCGGCTTCTA
CACGCAGGAACAGATCAGCGAAGTGGTGGCCTACGCGGCGCGCCTGCACATCACCGTGCTGCCCGAGCTGGATATGCCCG
GGCATGCGCAGGCGGCCGTTGCCGCCTACCCCGAAGAGGTGGGCGTCCCCGGTGTGCGCACCCAGGTGGGTGTGGACTGG
GGCGTCAACCCGTACCTGTTCAACACCAGCGAACGCAGCCTGACCTTCATCACCAATGTGCTGGATGAAGTGCTCACGCT
GTTCCCGTCGACCTACATCCACATCGGCGGCGATGAGGCAGTCAAGGACCAATGGGAAGCCTCGCCGGCCGTTCGCGCAC
AGATGCGCAAGCTCGGCGTCAAGGACGCACACGCGATGCAAGGCTGGTTCAACGAACAGCTGGCCCAGTACCTCACCCAG
CATGGCCGGCGCATGATCGGCTGGGACGAAATCCTCGAAGGCGGCGTGCCGGCCAGCGCGGCCGTGATGTCCTGGCGTGG
CATCGAAGGCGCGGTGACCGCCGCCAAGCAAGGCCACGACGTGGTGCTGGCACCGGGCGATTCGCTGTATCTGGACAACC
TGCAGACCACGCGCAGCGATGAACCCAACGGCCGCCTGACCACGCTGCCGCTCTCGAAGGTCTACGCGTTCAACCCGGTG
CCGGCCGCGCTCAATGCCGAGCAGGCCAGGCATGTGCTCGGCGCGCAGGGCGCGTTGTGGGCCGAATACATTCCCTCGCG
CTGGCACGTCGACCACGCGCTGTTCCCGCGCCTGGCAGCGGTAGCCGAAGTGACGTGGTCGCCGATGGCCGCGCGCGACT
GGAAGAATTTCCTGGCGCGGATGCCGGCGCAGCTGCAGCGTTATCAGGCGCTGGGCATCGATTACAGCGATGGCGCGTTT
GCCGCCGACATCGATCTGGACGGCGACGTCAACGCGGTACTGGCCGGTGGCCCGGCCAAGGTATCGCTTGGCAACCAGAG
CGGCGCCGGCAGCCTGCACTACACCGTGGATGGCAGCGACCCCACGCCGGATGCACCGCGCTACACGGCGCCGTTCGCGA
TTCAGCTGCCCACCACCGTCAAGGCCACAGCCTTCACCGACGATGGCATTGCACTGGCCGCCCCACGCAGCCGCACCTTT
GACCGTGCCGCGCTGCTGAGCCGCGACACCCAGGGTCTGCGCCACTGTGTCGAGCAAGGGGCGCTGGGCCTGCGCCTGCC
GCTGCTGCCGGACCTGCCGGGCGCCGACACGCCGGTCTACAACGTGGACCTGTTCCATGCCTGCCGCCTGTATCCGCAGG
CGCGGCTGGATGGTGTGGGCGCGATCAAGGTGGACGCCGCACGCCTGGCGCGCAACTTCGGCCTGGCGCACGAGCAGTCC
AAGGTGCAGAAGTACCCGGCCAAGACACCCGGCGGCGAACTCGAAGTGCGCCTGGGTTGCGAAGGCGAGCTGCTCGCGCG
CATCCCGCTGCCCAAGGGCAACGCGCTCGGCGAACAATTCACACTGGAAAGCGCGCTGCCTGCACGCACCGGCACGCACG
ATCTGTGCCTGCGCTTCACCGCCCCCATCACCGGCCCGTTGTATGCCATCGGCGCCGTCCATCTGATTGAAACCACCGCG
CAGGCGCCCCCCGCCGCCACGCGCTGA

Upstream 100 bases:

>100_bases
GTGGCTGCCGTGTCCTGGCGCGTGGCAAGCTGCATGACACGCGCTGATTGCCACATCGGGATGTGATTGCATGATCTCCA
ACACCGGCCCTGTTCCACGC

Downstream 100 bases:

>100_bases
TCCCTCCAAGGAGAACCCTGCATGTCCCTGTCCCGCCACCGTCGTGTTCCTGCACCCGCCCGCCTCGGGCTTGCCCTCGC
CTTCGCCATGTCGCAGGCCT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MMSSRRLLSTRLPSRLLVCCVAVSALLGCGQREAGTAPAVASAGAPAAPAANTPLPLIPAPAQVTRGSGSFHIGAGTVIS
IVGGDADARRSAEYLAELLKRTRGLSLEVRNETSASPGSIRLERSAQAPVAQKEGYSLDSDAKGLRIQARDGAGLFYGTV
SAWQLMTPDARKGDVEVPAVAIRDWPRFSWRGQHLDVARHFHDVATVKHVLDTMAVHKLNVLHWHLTDDQGWRIEIKRYP
KLTEVGAWRTPPGAGQHGTPERYGGFYTQEQISEVVAYAARLHITVLPELDMPGHAQAAVAAYPEEVGVPGVRTQVGVDW
GVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQWEASPAVRAQMRKLGVKDAHAMQGWFNEQLAQYLTQ
HGRRMIGWDEILEGGVPASAAVMSWRGIEGAVTAAKQGHDVVLAPGDSLYLDNLQTTRSDEPNGRLTTLPLSKVYAFNPV
PAALNAEQARHVLGAQGALWAEYIPSRWHVDHALFPRLAAVAEVTWSPMAARDWKNFLARMPAQLQRYQALGIDYSDGAF
AADIDLDGDVNAVLAGGPAKVSLGNQSGAGSLHYTVDGSDPTPDAPRYTAPFAIQLPTTVKATAFTDDGIALAAPRSRTF
DRAALLSRDTQGLRHCVEQGALGLRLPLLPDLPGADTPVYNVDLFHACRLYPQARLDGVGAIKVDAARLARNFGLAHEQS
KVQKYPAKTPGGELEVRLGCEGELLARIPLPKGNALGEQFTLESALPARTGTHDLCLRFTAPITGPLYAIGAVHLIETTA
QAPPAATR

Sequences:

>Translated_808_residues
MMSSRRLLSTRLPSRLLVCCVAVSALLGCGQREAGTAPAVASAGAPAAPAANTPLPLIPAPAQVTRGSGSFHIGAGTVIS
IVGGDADARRSAEYLAELLKRTRGLSLEVRNETSASPGSIRLERSAQAPVAQKEGYSLDSDAKGLRIQARDGAGLFYGTV
SAWQLMTPDARKGDVEVPAVAIRDWPRFSWRGQHLDVARHFHDVATVKHVLDTMAVHKLNVLHWHLTDDQGWRIEIKRYP
KLTEVGAWRTPPGAGQHGTPERYGGFYTQEQISEVVAYAARLHITVLPELDMPGHAQAAVAAYPEEVGVPGVRTQVGVDW
GVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQWEASPAVRAQMRKLGVKDAHAMQGWFNEQLAQYLTQ
HGRRMIGWDEILEGGVPASAAVMSWRGIEGAVTAAKQGHDVVLAPGDSLYLDNLQTTRSDEPNGRLTTLPLSKVYAFNPV
PAALNAEQARHVLGAQGALWAEYIPSRWHVDHALFPRLAAVAEVTWSPMAARDWKNFLARMPAQLQRYQALGIDYSDGAF
AADIDLDGDVNAVLAGGPAKVSLGNQSGAGSLHYTVDGSDPTPDAPRYTAPFAIQLPTTVKATAFTDDGIALAAPRSRTF
DRAALLSRDTQGLRHCVEQGALGLRLPLLPDLPGADTPVYNVDLFHACRLYPQARLDGVGAIKVDAARLARNFGLAHEQS
KVQKYPAKTPGGELEVRLGCEGELLARIPLPKGNALGEQFTLESALPARTGTHDLCLRFTAPITGPLYAIGAVHLIETTA
QAPPAATR
>Mature_808_residues
MMSSRRLLSTRLPSRLLVCCVAVSALLGCGQREAGTAPAVASAGAPAAPAANTPLPLIPAPAQVTRGSGSFHIGAGTVIS
IVGGDADARRSAEYLAELLKRTRGLSLEVRNETSASPGSIRLERSAQAPVAQKEGYSLDSDAKGLRIQARDGAGLFYGTV
SAWQLMTPDARKGDVEVPAVAIRDWPRFSWRGQHLDVARHFHDVATVKHVLDTMAVHKLNVLHWHLTDDQGWRIEIKRYP
KLTEVGAWRTPPGAGQHGTPERYGGFYTQEQISEVVAYAARLHITVLPELDMPGHAQAAVAAYPEEVGVPGVRTQVGVDW
GVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEAVKDQWEASPAVRAQMRKLGVKDAHAMQGWFNEQLAQYLTQ
HGRRMIGWDEILEGGVPASAAVMSWRGIEGAVTAAKQGHDVVLAPGDSLYLDNLQTTRSDEPNGRLTTLPLSKVYAFNPV
PAALNAEQARHVLGAQGALWAEYIPSRWHVDHALFPRLAAVAEVTWSPMAARDWKNFLARMPAQLQRYQALGIDYSDGAF
AADIDLDGDVNAVLAGGPAKVSLGNQSGAGSLHYTVDGSDPTPDAPRYTAPFAIQLPTTVKATAFTDDGIALAAPRSRTF
DRAALLSRDTQGLRHCVEQGALGLRLPLLPDLPGADTPVYNVDLFHACRLYPQARLDGVGAIKVDAARLARNFGLAHEQS
KVQKYPAKTPGGELEVRLGCEGELLARIPLPKGNALGEQFTLESALPARTGTHDLCLRFTAPITGPLYAIGAVHLIETTA
QAPPAATR

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=543, Percent_Identity=25.2302025782689, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI189181666, Length=423, Percent_Identity=28.1323877068558, Blast_Score=146, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17569815, Length=412, Percent_Identity=28.6407766990291, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24657468, Length=452, Percent_Identity=26.9911504424779, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17647501, Length=452, Percent_Identity=26.9911504424779, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281365639, Length=474, Percent_Identity=26.7932489451477, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24657474, Length=474, Percent_Identity=26.7932489451477, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17933586, Length=423, Percent_Identity=26.0047281323877, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24653074, Length=421, Percent_Identity=24.7030878859857, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45551090, Length=421, Percent_Identity=24.7030878859857, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 86877; Mature: 86877

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSRRLLSTRLPSRLLVCCVAVSALLGCGQREAGTAPAVASAGAPAAPAANTPLPLIPA
CCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
PAQVTRGSGSFHIGAGTVISIVGGDADARRSAEYLAELLKRTRGLSLEVRNETSASPGSI
CHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCE
RLERSAQAPVAQKEGYSLDSDAKGLRIQARDGAGLFYGTVSAWQLMTPDARKGDVEVPAV
EEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCEE
AIRDWPRFSWRGQHLDVARHFHDVATVKHVLDTMAVHKLNVLHWHLTDDQGWRIEIKRYP
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCC
KLTEVGAWRTPPGAGQHGTPERYGGFYTQEQISEVVAYAARLHITVLPELDMPGHAQAAV
CHHHCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHH
AAYPEEVGVPGVRTQVGVDWGVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEA
HCCHHHHCCCCCEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHH
VKDQWEASPAVRAQMRKLGVKDAHAMQGWFNEQLAQYLTQHGRRMIGWDEILEGGVPASA
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHH
AVMSWRGIEGAVTAAKQGHDVVLAPGDSLYLDNLQTTRSDEPNGRLTTLPLSKVYAFNPV
HHHEECCCCHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCCCCEEEEEHHHEEECCCC
PAALNAEQARHVLGAQGALWAEYIPSRWHVDHALFPRLAAVAEVTWSPMAARDWKNFLAR
CCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MPAQLQRYQALGIDYSDGAFAADIDLDGDVNAVLAGGPAKVSLGNQSGAGSLHYTVDGSD
CHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCEEEEECCCCCCCEEEEEECCCC
PTPDAPRYTAPFAIQLPTTVKATAFTDDGIALAAPRSRTFDRAALLSRDTQGLRHCVEQG
CCCCCCCCCCCEEEECCCEEEEEEECCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHCC
ALGLRLPLLPDLPGADTPVYNVDLFHACRLYPQARLDGVGAIKVDAARLARNFGLAHEQS
CCEEECCCCCCCCCCCCCEEEEHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHCCCHHHH
KVQKYPAKTPGGELEVRLGCEGELLARIPLPKGNALGEQFTLESALPARTGTHDLCLRFT
HHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEHHHCCCCCCCCCCEEEEEE
APITGPLYAIGAVHLIETTAQAPPAATR
CCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMSSRRLLSTRLPSRLLVCCVAVSALLGCGQREAGTAPAVASAGAPAAPAANTPLPLIPA
CCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
PAQVTRGSGSFHIGAGTVISIVGGDADARRSAEYLAELLKRTRGLSLEVRNETSASPGSI
CHHHCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCE
RLERSAQAPVAQKEGYSLDSDAKGLRIQARDGAGLFYGTVSAWQLMTPDARKGDVEVPAV
EEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCEEEEECCCEEEEECCCCCCCCCCCCEE
AIRDWPRFSWRGQHLDVARHFHDVATVKHVLDTMAVHKLNVLHWHLTDDQGWRIEIKRYP
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCC
KLTEVGAWRTPPGAGQHGTPERYGGFYTQEQISEVVAYAARLHITVLPELDMPGHAQAAV
CHHHCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHH
AAYPEEVGVPGVRTQVGVDWGVNPYLFNTSERSLTFITNVLDEVLTLFPSTYIHIGGDEA
HCCHHHHCCCCCEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHH
VKDQWEASPAVRAQMRKLGVKDAHAMQGWFNEQLAQYLTQHGRRMIGWDEILEGGVPASA
HHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCHH
AVMSWRGIEGAVTAAKQGHDVVLAPGDSLYLDNLQTTRSDEPNGRLTTLPLSKVYAFNPV
HHHEECCCCHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCCCCEEEEEHHHEEECCCC
PAALNAEQARHVLGAQGALWAEYIPSRWHVDHALFPRLAAVAEVTWSPMAARDWKNFLAR
CCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MPAQLQRYQALGIDYSDGAFAADIDLDGDVNAVLAGGPAKVSLGNQSGAGSLHYTVDGSD
CHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCEEEEECCCCCCCEEEEEECCCC
PTPDAPRYTAPFAIQLPTTVKATAFTDDGIALAAPRSRTFDRAALLSRDTQGLRHCVEQG
CCCCCCCCCCCEEEECCCEEEEEEECCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHCC
ALGLRLPLLPDLPGADTPVYNVDLFHACRLYPQARLDGVGAIKVDAARLARNFGLAHEQS
CCEEECCCCCCCCCCCCCEEEEHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHCCCHHHH
KVQKYPAKTPGGELEVRLGCEGELLARIPLPKGNALGEQFTLESALPARTGTHDLCLRFT
HHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEHHHCCCCCCCCCCEEEEEE
APITGPLYAIGAVHLIETTAQAPPAATR
CCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]