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The map label for this gene is hsdS [C]

Identifier: 66767532

GI number: 66767532

Start: 1464058

End: 1465305

Strand: Reverse

Name: hsdS [C]

Synonym: XC_1205

Alternate gene names: 66767532

Gene position: 1465305-1464058 (Counterclockwise)

Preceding gene: 66767533

Following gene: 66767531

Centisome position: 28.46

GC content: 49.04

Gene sequence:

>1248_bases
ATGCTTCCTGACGGCTGGCGACGCACAACGCTTGGGAATATTGGCTCCGTCAAATCTGGCAGCACGCCCGCACGCTCTCA
ACATGACCGCTATTTCGTAGATGGAAAGTGGCCATGGGTTAAAACCATGGACCTCACAAATTCAGAGATATTAACAACAG
ACGAAGTCATCACCGATGCAGCGCTCGCGGAATCTTCTTGCAGGCTTTTCCCTGCCGGCACCGTCTTAGTCGCCATGTAC
GGAGGCTTCAAGCAAATCGGCCGCACAGGGCTATTGCGAGAGAAAAGCGCTATCAATCAAGCGATCTCTGCAATTGATAT
TGAACGAAACCAAGCGGACCCAGAGTTTGTCTTACATTGGCTAAATGGAAGCGTTGAGACGTGGAAAAACTACGCTGCCA
GCAGCAGAAAAGATCCAAACATCACACGCGAAAACGTATGTGACTTTCCGGTCATTCTGCCCACTTTGGGAGAACAACGC
CGCATCGCCCACATTCTCTCCACCTGGGATCAAGCCATCGCCACCACGGAACGATTGCTTAAAAATAGCCAGAAGCAAAT
GGACATACTTCTGCGCGACCTAACTCTCGGGACACAGCGAACAACCTCGACACCTTCACCTTGGGCAAAGTTCACACTTG
GTGAGCTTGGTCGGACTTATAGCGGCCTTTCCGGAAAAAAAGGCGAGGACTTTGGATTCGGCGCTAAATTCATCCCATAC
ACCAACGTTTTCAAAAATAATCGTATTGACATTGAAGACTTTTCCTTAGTAAAAATATCGGAAAACGAAAACCAAACTCG
AGTCAAGTCAGGAGACATTATTTTCACAATTTCTTCTGAAACACCCAATGAGGTCGGCATGGCATCGGTACTGCTTGATG
ACGTGAACGAACTTTACTTGAATAGTTTTTGCTTTGGATATCGACTAAACGACTTCAAAACCTTATTGCCAGAATATGCA
GGATTTGTACTGCGCGCACCTCATATTAGGGCTCTCATGACACAAATCGCGCAAGGCTCGACTCGCTTCAATATTTCCAA
AGCGAATGTGATGCGCATGGAACTCGCCCTTCCATCTATTGCCGAGCAAAAGCGCATAGCATCGATCCTCGGCGGAGCCC
ATTCAACAGTAAAAAACCTCCGCGATCAGCTTGCTCGACTCAAGGCGGAAAAAGTCATTCTGATGTCCCAACTCCTCACC
GGCAAACGCCGCGTGCGCCTGCCCACCGACGAAGCCGCACACGCATGA

Upstream 100 bases:

>100_bases
ACTGCCGCCGACGGCCAGAAGACCGCTGCGCAACGCATGGTCGAACGCGCTGACCTCAACCAGCCCAACATGGTGCTGAA
AATTAAAATTAGGAAAAGTG

Downstream 100 bases:

>100_bases
CCCACAGCGCCCCGGACACCCGCGAACAGGCCAGCGCGCAGCTGCCCGCATTGCACCTGCTATGCAACCTGGGCTGGCGC
TACCTGAGCAGTGCGCACTG

Product: type I restriction enzyme specificity chain-like protein

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MLPDGWRRTTLGNIGSVKSGSTPARSQHDRYFVDGKWPWVKTMDLTNSEILTTDEVITDAALAESSCRLFPAGTVLVAMY
GGFKQIGRTGLLREKSAINQAISAIDIERNQADPEFVLHWLNGSVETWKNYAASSRKDPNITRENVCDFPVILPTLGEQR
RIAHILSTWDQAIATTERLLKNSQKQMDILLRDLTLGTQRTTSTPSPWAKFTLGELGRTYSGLSGKKGEDFGFGAKFIPY
TNVFKNNRIDIEDFSLVKISENENQTRVKSGDIIFTISSETPNEVGMASVLLDDVNELYLNSFCFGYRLNDFKTLLPEYA
GFVLRAPHIRALMTQIAQGSTRFNISKANVMRMELALPSIAEQKRIASILGGAHSTVKNLRDQLARLKAEKVILMSQLLT
GKRRVRLPTDEAAHA

Sequences:

>Translated_415_residues
MLPDGWRRTTLGNIGSVKSGSTPARSQHDRYFVDGKWPWVKTMDLTNSEILTTDEVITDAALAESSCRLFPAGTVLVAMY
GGFKQIGRTGLLREKSAINQAISAIDIERNQADPEFVLHWLNGSVETWKNYAASSRKDPNITRENVCDFPVILPTLGEQR
RIAHILSTWDQAIATTERLLKNSQKQMDILLRDLTLGTQRTTSTPSPWAKFTLGELGRTYSGLSGKKGEDFGFGAKFIPY
TNVFKNNRIDIEDFSLVKISENENQTRVKSGDIIFTISSETPNEVGMASVLLDDVNELYLNSFCFGYRLNDFKTLLPEYA
GFVLRAPHIRALMTQIAQGSTRFNISKANVMRMELALPSIAEQKRIASILGGAHSTVKNLRDQLARLKAEKVILMSQLLT
GKRRVRLPTDEAAHA
>Mature_415_residues
MLPDGWRRTTLGNIGSVKSGSTPARSQHDRYFVDGKWPWVKTMDLTNSEILTTDEVITDAALAESSCRLFPAGTVLVAMY
GGFKQIGRTGLLREKSAINQAISAIDIERNQADPEFVLHWLNGSVETWKNYAASSRKDPNITRENVCDFPVILPTLGEQR
RIAHILSTWDQAIATTERLLKNSQKQMDILLRDLTLGTQRTTSTPSPWAKFTLGELGRTYSGLSGKKGEDFGFGAKFIPY
TNVFKNNRIDIEDFSLVKISENENQTRVKSGDIIFTISSETPNEVGMASVLLDDVNELYLNSFCFGYRLNDFKTLLPEYA
GFVLRAPHIRALMTQIAQGSTRFNISKANVMRMELALPSIAEQKRIASILGGAHSTVKNLRDQLARLKAEKVILMSQLLT
GKRRVRLPTDEAAHA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

Organism=Escherichia coli, GI1790807, Length=423, Percent_Identity=23.1678486997636, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 46317; Mature: 46317

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDGWRRTTLGNIGSVKSGSTPARSQHDRYFVDGKWPWVKTMDLTNSEILTTDEVITDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCEEEHHHHHHHH
ALAESSCRLFPAGTVLVAMYGGFKQIGRTGLLREKSAINQAISAIDIERNQADPEFVLHW
HHHHCCCEEEECCCEEHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LNGSVETWKNYAASSRKDPNITRENVCDFPVILPTLGEQRRIAHILSTWDQAIATTERLL
HCCCHHHHHHHHHCCCCCCCCCHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KNSQKQMDILLRDLTLGTQRTTSTPSPWAKFTLGELGRTYSGLSGKKGEDFGFGAKFIPY
HCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCC
TNVFKNNRIDIEDFSLVKISENENQTRVKSGDIIFTISSETPNEVGMASVLLDDVNELYL
HHHHCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
NSFCFGYRLNDFKTLLPEYAGFVLRAPHIRALMTQIAQGSTRFNISKANVMRMELALPSI
HHHHHCEECHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCEEEEEHHHEEEEEHHCCHH
AEQKRIASILGGAHSTVKNLRDQLARLKAEKVILMSQLLTGKRRVRLPTDEAAHA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCC
>Mature Secondary Structure
MLPDGWRRTTLGNIGSVKSGSTPARSQHDRYFVDGKWPWVKTMDLTNSEILTTDEVITDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCEEEHHHHHHHH
ALAESSCRLFPAGTVLVAMYGGFKQIGRTGLLREKSAINQAISAIDIERNQADPEFVLHW
HHHHCCCEEEECCCEEHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LNGSVETWKNYAASSRKDPNITRENVCDFPVILPTLGEQRRIAHILSTWDQAIATTERLL
HCCCHHHHHHHHHCCCCCCCCCHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KNSQKQMDILLRDLTLGTQRTTSTPSPWAKFTLGELGRTYSGLSGKKGEDFGFGAKFIPY
HCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCC
TNVFKNNRIDIEDFSLVKISENENQTRVKSGDIIFTISSETPNEVGMASVLLDDVNELYL
HHHHCCCCCCCCCCEEEEEECCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
NSFCFGYRLNDFKTLLPEYAGFVLRAPHIRALMTQIAQGSTRFNISKANVMRMELALPSI
HHHHHCEECHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCEEEEEHHHEEEEEHHCCHH
AEQKRIASILGGAHSTVKNLRDQLARLKAEKVILMSQLLTGKRRVRLPTDEAAHA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]