Click here to switch to the map view.

The map label for this gene is btuB [H]

Identifier: 66767407

GI number: 66767407

Start: 1301163

End: 1303598

Strand: Reverse

Name: btuB [H]

Synonym: XC_1079

Alternate gene names: 66767407

Gene position: 1303598-1301163 (Counterclockwise)

Preceding gene: 66767413

Following gene: 66767406

Centisome position: 25.32

GC content: 66.38

Gene sequence:

>2436_bases
ATGACCCGCCCCACCCTTTCGGTTATCGGCCTGGCCGTGGCCGCCGTCCTCAGCGCCAACGCCCAGGCCCAGCAAGCCGC
GCCCGGCGCCACCACGCTGGACACGGTGATCGTCACCGGCACCCGTGCCAGCGACCGCACCGTGCTCGAATCCACGGTGC
CGGTGGACGTGCTCACCGCCGAGGACATCCGCAAGGCCGGCGTGGTCAACGGTGAACTGGGCAGCGCGCTGCAGGCGCTG
CTGCCATCCTTCAACTTCCCGCGCCAGTCCAACTCCGGTGGTGCCGACCACATCCGCGCCGCACAGCTGCGTGGGCTCTC
GCCCGATCAGGTGCTGGTGCTGGTCAACGGCAAGCGCCGGCATACCTCGGCGCTGGTCAATACCGACAGCAAGATCGGCA
AGGGCACCACGCCGGTGGATTTCAATTCCATCCCGATCAACGCCATCAAGCGCATCGAAGTGCTGCGCGACGGCGCCGGC
GCGCAATACGGCTCCGATGCCATCGCCGGGGTCATCAATGTCATCCTGGACGACAACCCCGAGCGCGGTGAACTGGAAGC
CAGCTTCGGTGCGTACAACACCGATGTGGAGCCGATCAATCGGCGCGTCACCGATGGCCAGACCAGCTACGCCAGCGCCA
AGGTCGGCACGCTGCTGGGCGACGACGGTGGCTTCTTCAAGGTGGGCCTGGAGCTGAAGAACCGCGAGGCCACCAACCGC
GCCGGCTTCGATCAGATTCCGCCGTTCGAAGAACAGACCCCCGCCAACCTGGCCCTGGCCGGCCAGCGCAACTACGTGCT
CGGCGATGGCGCCACCAAGGGCCTGAACGCCTGGCTCAACACCAAGATTCCGTTCAGTGCCACCGGCGAGTTCTACGCCT
TCGGTACCTACAACCAGCGCGACACCGAAGGCGCCAATTACTTCCGTTACCCGGACAGCAGCGCCAACTGGCGCGAGATC
TACCCCAACGGCTACCGCCCGATTTCCGAAGGCGAAAACCGCGACCTGCAGATCGTGGCCGGCGCCCGCGGGCAATGGGG
CGACTGGGACTACGACGCCAGCCTGGATTACGGCCGCAACGACTTCACCTACCGGCTGCGCAACTCGCTCAACGCCTCGC
TCGGCCCGGGCAGCACCACGCGCTTCAAGACCGGTGATTTCGCCTTTGCGCAGACCGTGGGCAATTTCGATTTGACCCGC
GTGTTCGATGCGGCCGATGCCACCCACACCTTCGGCACCGGCGCCGAATTCCGCCGTGAGCAGTACCGCACGCATGCCGG
CGACCCGGCCAGCTACGCGGCCGGCCCGTTCACCGATCGCCCCACCGGCTCGCAGGCCGGCGGCGGGCTCACCCCGCAGG
ACGAGGCCGATCTGTCGCGCAATGTGGCCAGCGTCTACGCCAACGTGTCCAGCCAGTTCGGCGACAAGTTCTCCACCGAC
CTGGCCGGCCGCTACGAGCACTACCAGGATTTCGGCAGCCAGTGGACCGGCAAGCTGGCCGCACGCTACGCGTTCGCACC
GGCATTCGCGCTGCGCGGTGCGGTCTCCAACAACGTGCGTGCGCCCTCGCTGAGCCAGATCGGCTACGAAGCCACCTCCA
CCGGCTACGACGCCGCGGGCCGCCTGACCCAGGGCCGCCTGCTGTCGGTCAACAACCCGATCGCCCGCGCGCTCGGTGCC
ACCGATCTGAAGCCGGAAAAGTCGATCAACGCCAGCCTGGGTTTCACCAGCAAGCTGGGCGATCACTTCGACCTGTCGCT
GGACTTTTTCCAGATCGACATCGACGACCGCATCGCGCTGTCCGAAGACATCACCGGCAGCAGCCTCACCGATTTCGTGC
AGCAGAACTTCGGCGTCACCGGCGTGCAGAGCGCCAGCTACTTCCTCAACGCCGCCGACACCCGCACCCGCGGCGCCGAG
CTGGTCGCCAACTGGCGCCAGTACGCCTTCGGCGGCGACCTGCTGCTGACCGGCACCTACAGCTATGCCAAGACCGAGTT
GAAGAACGTCATCGCCACGCCGTCGCAACTGCTGGCGCTGGATCCGGACTACGTGCTGTTCGGCGTGGAAGAGAGCAACA
CGCTCACCGATGCAGCCCCGCGCACCCGCGCATCGCTCGCCGCCAACTGGAGCAACGAGCACTGGAACCTGCAGAGCCGC
ATCAACCGCTACGGCAGCGCCACCCGCGTGTTCGACTTCGGTGCCGGCTTCGTGCCGCGCCAGACCTACGGTGCGGAATG
GCAGTTGGACCTGGAAGCCGAATACCGCCTGGGCACGCAATGGACGCTGGCGATCGGCGGCCAGAACATCCTGGACAACT
ACTCGGACCGCTCCATCGACGACATCGCCTACTTCGGCAACCTGCCCTACGACGTGCTATCGCCGATCGGCAGCAATGGC
GCGTACTGGTATGGACGGGTGCGGTATAGCTTCTGA

Upstream 100 bases:

>100_bases
TCTCCATCCGGATGGAAGTGGAACACTCCCGGCCCCCACCTTGCACGCCAGCGCGGCCGGATGCCGACGCGCGGCGGCCT
GCCGTATTTCAGGAGACAGC

Downstream 100 bases:

>100_bases
GCGAAAGCGAAGAGCTTGAGACCTCTCTCCTCAGAGAGACTGCTTTAGCCCCTCTCCTACGGGAGAGGGGTTGGGGTGAG
GGTAAGGAGCGAAGCCCTCG

Product: ferric enterobactin receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MTRPTLSVIGLAVAAVLSANAQAQQAAPGATTLDTVIVTGTRASDRTVLESTVPVDVLTAEDIRKAGVVNGELGSALQAL
LPSFNFPRQSNSGGADHIRAAQLRGLSPDQVLVLVNGKRRHTSALVNTDSKIGKGTTPVDFNSIPINAIKRIEVLRDGAG
AQYGSDAIAGVINVILDDNPERGELEASFGAYNTDVEPINRRVTDGQTSYASAKVGTLLGDDGGFFKVGLELKNREATNR
AGFDQIPPFEEQTPANLALAGQRNYVLGDGATKGLNAWLNTKIPFSATGEFYAFGTYNQRDTEGANYFRYPDSSANWREI
YPNGYRPISEGENRDLQIVAGARGQWGDWDYDASLDYGRNDFTYRLRNSLNASLGPGSTTRFKTGDFAFAQTVGNFDLTR
VFDAADATHTFGTGAEFRREQYRTHAGDPASYAAGPFTDRPTGSQAGGGLTPQDEADLSRNVASVYANVSSQFGDKFSTD
LAGRYEHYQDFGSQWTGKLAARYAFAPAFALRGAVSNNVRAPSLSQIGYEATSTGYDAAGRLTQGRLLSVNNPIARALGA
TDLKPEKSINASLGFTSKLGDHFDLSLDFFQIDIDDRIALSEDITGSSLTDFVQQNFGVTGVQSASYFLNAADTRTRGAE
LVANWRQYAFGGDLLLTGTYSYAKTELKNVIATPSQLLALDPDYVLFGVEESNTLTDAAPRTRASLAANWSNEHWNLQSR
INRYGSATRVFDFGAGFVPRQTYGAEWQLDLEAEYRLGTQWTLAIGGQNILDNYSDRSIDDIAYFGNLPYDVLSPIGSNG
AYWYGRVRYSF

Sequences:

>Translated_811_residues
MTRPTLSVIGLAVAAVLSANAQAQQAAPGATTLDTVIVTGTRASDRTVLESTVPVDVLTAEDIRKAGVVNGELGSALQAL
LPSFNFPRQSNSGGADHIRAAQLRGLSPDQVLVLVNGKRRHTSALVNTDSKIGKGTTPVDFNSIPINAIKRIEVLRDGAG
AQYGSDAIAGVINVILDDNPERGELEASFGAYNTDVEPINRRVTDGQTSYASAKVGTLLGDDGGFFKVGLELKNREATNR
AGFDQIPPFEEQTPANLALAGQRNYVLGDGATKGLNAWLNTKIPFSATGEFYAFGTYNQRDTEGANYFRYPDSSANWREI
YPNGYRPISEGENRDLQIVAGARGQWGDWDYDASLDYGRNDFTYRLRNSLNASLGPGSTTRFKTGDFAFAQTVGNFDLTR
VFDAADATHTFGTGAEFRREQYRTHAGDPASYAAGPFTDRPTGSQAGGGLTPQDEADLSRNVASVYANVSSQFGDKFSTD
LAGRYEHYQDFGSQWTGKLAARYAFAPAFALRGAVSNNVRAPSLSQIGYEATSTGYDAAGRLTQGRLLSVNNPIARALGA
TDLKPEKSINASLGFTSKLGDHFDLSLDFFQIDIDDRIALSEDITGSSLTDFVQQNFGVTGVQSASYFLNAADTRTRGAE
LVANWRQYAFGGDLLLTGTYSYAKTELKNVIATPSQLLALDPDYVLFGVEESNTLTDAAPRTRASLAANWSNEHWNLQSR
INRYGSATRVFDFGAGFVPRQTYGAEWQLDLEAEYRLGTQWTLAIGGQNILDNYSDRSIDDIAYFGNLPYDVLSPIGSNG
AYWYGRVRYSF
>Mature_810_residues
TRPTLSVIGLAVAAVLSANAQAQQAAPGATTLDTVIVTGTRASDRTVLESTVPVDVLTAEDIRKAGVVNGELGSALQALL
PSFNFPRQSNSGGADHIRAAQLRGLSPDQVLVLVNGKRRHTSALVNTDSKIGKGTTPVDFNSIPINAIKRIEVLRDGAGA
QYGSDAIAGVINVILDDNPERGELEASFGAYNTDVEPINRRVTDGQTSYASAKVGTLLGDDGGFFKVGLELKNREATNRA
GFDQIPPFEEQTPANLALAGQRNYVLGDGATKGLNAWLNTKIPFSATGEFYAFGTYNQRDTEGANYFRYPDSSANWREIY
PNGYRPISEGENRDLQIVAGARGQWGDWDYDASLDYGRNDFTYRLRNSLNASLGPGSTTRFKTGDFAFAQTVGNFDLTRV
FDAADATHTFGTGAEFRREQYRTHAGDPASYAAGPFTDRPTGSQAGGGLTPQDEADLSRNVASVYANVSSQFGDKFSTDL
AGRYEHYQDFGSQWTGKLAARYAFAPAFALRGAVSNNVRAPSLSQIGYEATSTGYDAAGRLTQGRLLSVNNPIARALGAT
DLKPEKSINASLGFTSKLGDHFDLSLDFFQIDIDDRIALSEDITGSSLTDFVQQNFGVTGVQSASYFLNAADTRTRGAEL
VANWRQYAFGGDLLLTGTYSYAKTELKNVIATPSQLLALDPDYVLFGVEESNTLTDAAPRTRASLAANWSNEHWNLQSRI
NRYGSATRVFDFGAGFVPRQTYGAEWQLDLEAEYRLGTQWTLAIGGQNILDNYSDRSIDDIAYFGNLPYDVLSPIGSNGA
YWYGRVRYSF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=188, Percent_Identity=31.3829787234043, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1788478, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790405, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87799; Mature: 87668

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPTLSVIGLAVAAVLSANAQAQQAAPGATTLDTVIVTGTRASDRTVLESTVPVDVLTA
CCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEECCCCCCCEEECCCCCEEEEEH
EDIRKAGVVNGELGSALQALLPSFNFPRQSNSGGADHIRAAQLRGLSPDQVLVLVNGKRR
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
HTSALVNTDSKIGKGTTPVDFNSIPINAIKRIEVLRDGAGAQYGSDAIAGVINVILDDNP
CCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCC
ERGELEASFGAYNTDVEPINRRVTDGQTSYASAKVGTLLGDDGGFFKVGLELKNREATNR
CCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCEEECEEECCCCCEEEEEEEEECCCCCCC
AGFDQIPPFEEQTPANLALAGQRNYVLGDGATKGLNAWLNTKIPFSATGEFYAFGTYNQR
CCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHCCCCCCCCCCCCEEEEECCCCC
DTEGANYFRYPDSSANWREIYPNGYRPISEGENRDLQIVAGARGQWGDWDYDASLDYGRN
CCCCCCEEECCCCCCCHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DFTYRLRNSLNASLGPGSTTRFKTGDFAFAQTVGNFDLTRVFDAADATHTFGTGAEFRRE
CEEEHHHHCCCCCCCCCCCCEEECCCCCEEHHHCCCCHHHHECCCCCCCCCCCCHHHHHH
QYRTHAGDPASYAAGPFTDRPTGSQAGGGLTPQDEADLSRNVASVYANVSSQFGDKFSTD
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
LAGRYEHYQDFGSQWTGKLAARYAFAPAFALRGAVSNNVRAPSLSQIGYEATSTGYDAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCC
RLTQGRLLSVNNPIARALGATDLKPEKSINASLGFTSKLGDHFDLSLDFFQIDIDDRIAL
CCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEEEEECCCCEEE
SEDITGSSLTDFVQQNFGVTGVQSASYFLNAADTRTRGAELVANWRQYAFGGDLLLTGTY
CCCCCCCHHHHHHHHCCCCCEECCHHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECH
SYAKTELKNVIATPSQLLALDPDYVLFGVEESNTLTDAAPRTRASLAANWSNEHWNLQSR
HHHHHHHHHHHCCCHHHEEECCCEEEEEECCCCCCCCCCCCHHHHEEECCCCCCCCHHHH
INRYGSATRVFDFGAGFVPRQTYGAEWQLDLEAEYRLGTQWTLAIGGQNILDNYSDRSID
HHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECEECCCEEEEEECCCHHHCCCCCCCHH
DIAYFGNLPYDVLSPIGSNGAYWYGRVRYSF
HHHHHCCCCHHHHCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
TRPTLSVIGLAVAAVLSANAQAQQAAPGATTLDTVIVTGTRASDRTVLESTVPVDVLTA
CCCHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEECCCCCCCEEECCCCCEEEEEH
EDIRKAGVVNGELGSALQALLPSFNFPRQSNSGGADHIRAAQLRGLSPDQVLVLVNGKRR
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCC
HTSALVNTDSKIGKGTTPVDFNSIPINAIKRIEVLRDGAGAQYGSDAIAGVINVILDDNP
CCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCC
ERGELEASFGAYNTDVEPINRRVTDGQTSYASAKVGTLLGDDGGFFKVGLELKNREATNR
CCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCEEECEEECCCCCEEEEEEEEECCCCCCC
AGFDQIPPFEEQTPANLALAGQRNYVLGDGATKGLNAWLNTKIPFSATGEFYAFGTYNQR
CCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHCCCCCCCCCCCCEEEEECCCCC
DTEGANYFRYPDSSANWREIYPNGYRPISEGENRDLQIVAGARGQWGDWDYDASLDYGRN
CCCCCCEEECCCCCCCHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DFTYRLRNSLNASLGPGSTTRFKTGDFAFAQTVGNFDLTRVFDAADATHTFGTGAEFRRE
CEEEHHHHCCCCCCCCCCCCEEECCCCCEEHHHCCCCHHHHECCCCCCCCCCCCHHHHHH
QYRTHAGDPASYAAGPFTDRPTGSQAGGGLTPQDEADLSRNVASVYANVSSQFGDKFSTD
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
LAGRYEHYQDFGSQWTGKLAARYAFAPAFALRGAVSNNVRAPSLSQIGYEATSTGYDAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCC
RLTQGRLLSVNNPIARALGATDLKPEKSINASLGFTSKLGDHFDLSLDFFQIDIDDRIAL
CCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEEEEECCCCEEE
SEDITGSSLTDFVQQNFGVTGVQSASYFLNAADTRTRGAELVANWRQYAFGGDLLLTGTY
CCCCCCCHHHHHHHHCCCCCEECCHHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECH
SYAKTELKNVIATPSQLLALDPDYVLFGVEESNTLTDAAPRTRASLAANWSNEHWNLQSR
HHHHHHHHHHHCCCHHHEEECCCEEEEEECCCCCCCCCCCCHHHHEEECCCCCCCCHHHH
INRYGSATRVFDFGAGFVPRQTYGAEWQLDLEAEYRLGTQWTLAIGGQNILDNYSDRSID
HHHCCCCEEEEECCCCCCCCCCCCCCEEEEEEECEECCCEEEEEECCCHHHCCCCCCCHH
DIAYFGNLPYDVLSPIGSNGAYWYGRVRYSF
HHHHHCCCCHHHHCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA