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The map label for this gene is recG [H]

Identifier: 66767279

GI number: 66767279

Start: 1136662

End: 1138803

Strand: Reverse

Name: recG [H]

Synonym: XC_0947

Alternate gene names: 66767279

Gene position: 1138803-1136662 (Counterclockwise)

Preceding gene: 66767280

Following gene: 66767278

Centisome position: 22.12

GC content: 69.37

Gene sequence:

>2142_bases
GTGCCGCGCGCGCGTTCCGTCACCCCAAGCCTGGCCGTCGCTGGCCAGGCGCCGCTTTCCAGCTTGCCCGGGGTCGGCCC
GAAAGTGGCCGAGAAATTTGCCGCGCGCGGCATTCTCAGCCTGCAGGATCTGTGGCTGCACCTGCCGCTGCGCTACGAAG
ACCGCACCCGCCTGACCACCATCGCGCAGTTGCAGGGCGGGGTACCGGCGCAGATCGAGGGGCGTGTGGAGGCGATGGAG
CGCGGCTTCCGCTTTCGCCCGGTGTTGCGCGTGGCGATGTCGGACGACTCGTGCGGCACGCTGGTGCTGCGCTTCTTCCA
CTTTCGCGCGGCCCAGGTTGCGCAGTTTTCCCCGGGCACGCGCTTGCGCGTGTTCGGCACGCCCAAGCCCGGCCAGAACG
GCTGGGAAATCGTTCACCCCAGTTACCGCGTCCTGGCGCCGGATGAAGATGCGGGCCTGGGCGATTGCCTGGACCCGGTG
TATCCGGTGCTGGAAGGTGTCGGGCCGGCCACGCTGCGCAAGCTGATCGGCCAGGCATTGGAGCGCTTGCCGCCGGAGGC
CGCGCTGGAACTGCTGCCGCCGCACTGGTTGCAGGACGAACAGCTGCCGTCGCTACGCAGCGCGCTGCTGACCATGCATC
GCCCACCGGTGGACACCGACCCGCAGCAACTGCTGGCCGGCGGACATCCGGCGCAACAGCGATTGGCCATCGAAGAACTG
CTGGCGCATCAAGTGAGCCTGCGCCGGCAACGCATCGCGCTGCAGCGCTTCCGCGCACCGCAGTTGCGCGGTGGCCGCTT
GGTGCAGCAGTTACGCAAGGCCTTGCCGTTCCAGCTCACCGGCGCGCAGCAGCGCGTGTTCGAGCAGATCGCCCACGATC
TGGCGCAGCCGGCACCGATGCTGCGGCTGGTGCAGGGCGATGTGGGCAGCGGCAAGACCGTGGTGGCGGCACTGGCCGCG
ATGTTGGCGGTCGAACACGGCAAACAAGTGGCCCTGGCTGCGCCCACCGAGCTGCTGGCCGAGCAGCATCTGGCCAACCT
GCGTGGCTGGCTGGAACCGCTGGGCGTGCGCATCGTCTGGCTGGCCGGCAAGGTCACCGGCAAGGCGCGCGTCGCGGCGA
TGGCCGAAGTAGCCTCCGGGCAGGCACAGGTGGTGGTGGGCACGCATGCGCTGATGCAGGACGCGGTGGTCTTCCACGAT
CTGGCGCTGGCCATCATCGACGAGCAGCACCGCTTCGGCGTGCATCAGCGCCTGGCGCTGCGCGACAAGGGCGCGGCTGC
CGGCAGCGTGCCGCATCAACTGGTGATGACCGCCACGCCGATCCCGCGCACGCTGGCAATGGCGGCCTACGCGGATCTGC
ACGTCTCGGCCATCGACGAACTGCCGCCCGGTCGCACGCCGGTGCAGACCATCGTGCTGAGCGCCGAGCGCCGGCCCGAG
CTGGTGGAGCGCATTCGCGCGGCCTGTGCCGAAGGCCGGCAGGCGTACTGGGTCTGTACCCTGATCGAAGAAAGCGAAGA
CACCGACAAGGGCGCGCAGAACGGCCCGCCGCGCATCGAAGCACAGGCCGCGCAGGTCACCTTCGAAACGCTCTCGGCGC
AACTGCCGGGCGTGCGCGTGGCGCTGGTACACGGGCGCATGAAACCGGCCGAAAAGCAGCAGGCCATGCTGGATTTCAAG
CAGGGCCGCACCGATCTGCTGGTCGCCACCACCGTGATCGAAGTGGGCGTGGATGTGCCCAACGCCTCGCTGATGATCAT
CGAGAACGCCGAGCGTCTCGGCCTGGCCCAGTTGCACCAGTTACGCGGGCGGGTCGGGCGCGGCGCGGCGGCGTCCAGCT
GCGTGCTGCTCTATCAGGGCCCGCTGTCGCTGATGGCACGCCAGCGGTTGGAGACCATGCGCCAGACCAACGATGGCTTC
GTGATTGCCGAAAGGGATCTGGAGCTGCGTGGCCCCGGCGAGTTGCTGGGTACGCGCCAGACCGGTCTGGCGAGTTTCCG
CATCGCCGACCTGGCGCGCGATGCCGGCCTGCTGCCGCGGGTGCAGGTGCTGGCGGAGCGCTTGCTCGACGAAGCGCCGG
AGATCGCCGACCGCGTGGTCGCACGCTGGATCGGTGGCGCAGTGCGGTATGCGGCCGCTTGA

Upstream 100 bases:

>100_bases
CCCGGCGCGCTCGACCATCGAGGTGTCGGGCCTGCCCAAGGGCGCTGGCTTCGAGGTCGACGCAGTGATGGTGCTCGACT
GACCGAAGGCGCGATTCGCC

Downstream 100 bases:

>100_bases
GTGGCGGGGATTGGGGATTTGGGAGTGGGGATTTGTCAGAGCGGGGCTGCTGCCTCATCTGATTCGCTTGCCTCGCCGAT
CCTTGCGAAGATGCGACAAC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MPRARSVTPSLAVAGQAPLSSLPGVGPKVAEKFAARGILSLQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVEAME
RGFRFRPVLRVAMSDDSCGTLVLRFFHFRAAQVAQFSPGTRLRVFGTPKPGQNGWEIVHPSYRVLAPDEDAGLGDCLDPV
YPVLEGVGPATLRKLIGQALERLPPEAALELLPPHWLQDEQLPSLRSALLTMHRPPVDTDPQQLLAGGHPAQQRLAIEEL
LAHQVSLRRQRIALQRFRAPQLRGGRLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPAPMLRLVQGDVGSGKTVVAALAA
MLAVEHGKQVALAAPTELLAEQHLANLRGWLEPLGVRIVWLAGKVTGKARVAAMAEVASGQAQVVVGTHALMQDAVVFHD
LALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMAAYADLHVSAIDELPPGRTPVQTIVLSAERRPE
LVERIRAACAEGRQAYWVCTLIEESEDTDKGAQNGPPRIEAQAAQVTFETLSAQLPGVRVALVHGRMKPAEKQQAMLDFK
QGRTDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQGPLSLMARQRLETMRQTNDGF
VIAERDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVARWIGGAVRYAAA

Sequences:

>Translated_713_residues
MPRARSVTPSLAVAGQAPLSSLPGVGPKVAEKFAARGILSLQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVEAME
RGFRFRPVLRVAMSDDSCGTLVLRFFHFRAAQVAQFSPGTRLRVFGTPKPGQNGWEIVHPSYRVLAPDEDAGLGDCLDPV
YPVLEGVGPATLRKLIGQALERLPPEAALELLPPHWLQDEQLPSLRSALLTMHRPPVDTDPQQLLAGGHPAQQRLAIEEL
LAHQVSLRRQRIALQRFRAPQLRGGRLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPAPMLRLVQGDVGSGKTVVAALAA
MLAVEHGKQVALAAPTELLAEQHLANLRGWLEPLGVRIVWLAGKVTGKARVAAMAEVASGQAQVVVGTHALMQDAVVFHD
LALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMAAYADLHVSAIDELPPGRTPVQTIVLSAERRPE
LVERIRAACAEGRQAYWVCTLIEESEDTDKGAQNGPPRIEAQAAQVTFETLSAQLPGVRVALVHGRMKPAEKQQAMLDFK
QGRTDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQGPLSLMARQRLETMRQTNDGF
VIAERDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVARWIGGAVRYAAA
>Mature_712_residues
PRARSVTPSLAVAGQAPLSSLPGVGPKVAEKFAARGILSLQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVEAMER
GFRFRPVLRVAMSDDSCGTLVLRFFHFRAAQVAQFSPGTRLRVFGTPKPGQNGWEIVHPSYRVLAPDEDAGLGDCLDPVY
PVLEGVGPATLRKLIGQALERLPPEAALELLPPHWLQDEQLPSLRSALLTMHRPPVDTDPQQLLAGGHPAQQRLAIEELL
AHQVSLRRQRIALQRFRAPQLRGGRLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPAPMLRLVQGDVGSGKTVVAALAAM
LAVEHGKQVALAAPTELLAEQHLANLRGWLEPLGVRIVWLAGKVTGKARVAAMAEVASGQAQVVVGTHALMQDAVVFHDL
ALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMAAYADLHVSAIDELPPGRTPVQTIVLSAERRPEL
VERIRAACAEGRQAYWVCTLIEESEDTDKGAQNGPPRIEAQAAQVTFETLSAQLPGVRVALVHGRMKPAEKQQAMLDFKQ
GRTDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQGPLSLMARQRLETMRQTNDGFV
IAERDLELRGPGELLGTRQTGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVARWIGGAVRYAAA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=698, Percent_Identity=57.163323782235, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=399, Percent_Identity=39.8496240601504, Blast_Score=249, Evalue=6e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77409; Mature: 77278

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRARSVTPSLAVAGQAPLSSLPGVGPKVAEKFAARGILSLQDLWLHLPLRYEDRTRLTT
CCCCCCCCCCCEECCCCCHHHCCCCCHHHHHHHHHCCCHHHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQIEGRVEAMERGFRFRPVLRVAMSDDSCGTLVLRFFHFRAAQVAQFSPGT
HHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCC
RLRVFGTPKPGQNGWEIVHPSYRVLAPDEDAGLGDCLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ERLPPEAALELLPPHWLQDEQLPSLRSALLTMHRPPVDTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQVSLRRQRIALQRFRAPQLRGGRLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPAPM
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCHH
LRLVQGDVGSGKTVVAALAAMLAVEHGKQVALAAPTELLAEQHLANLRGWLEPLGVRIVW
HHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCEEEEE
LAGKVTGKARVAAMAEVASGQAQVVVGTHALMQDAVVFHDLALAIIDEQHRFGVHQRLAL
EECCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
RDKGAAAGSVPHQLVMTATPIPRTLAMAAYADLHVSAIDELPPGRTPVQTIVLSAERRPE
HCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCHH
LVERIRAACAEGRQAYWVCTLIEESEDTDKGAQNGPPRIEAQAAQVTFETLSAQLPGVRV
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
ALVHGRMKPAEKQQAMLDFKQGRTDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQ
EEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHH
LRGRVGRGAAASSCVLLYQGPLSLMARQRLETMRQTNDGFVIAERDLELRGPGELLGTRQ
HHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCC
TGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVARWIGGAVRYAAA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRARSVTPSLAVAGQAPLSSLPGVGPKVAEKFAARGILSLQDLWLHLPLRYEDRTRLTT
CCCCCCCCCCEECCCCCHHHCCCCCHHHHHHHHHCCCHHHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQIEGRVEAMERGFRFRPVLRVAMSDDSCGTLVLRFFHFRAAQVAQFSPGT
HHHHCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCC
RLRVFGTPKPGQNGWEIVHPSYRVLAPDEDAGLGDCLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ERLPPEAALELLPPHWLQDEQLPSLRSALLTMHRPPVDTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQVSLRRQRIALQRFRAPQLRGGRLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPAPM
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCHH
LRLVQGDVGSGKTVVAALAAMLAVEHGKQVALAAPTELLAEQHLANLRGWLEPLGVRIVW
HHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCEEEEE
LAGKVTGKARVAAMAEVASGQAQVVVGTHALMQDAVVFHDLALAIIDEQHRFGVHQRLAL
EECCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
RDKGAAAGSVPHQLVMTATPIPRTLAMAAYADLHVSAIDELPPGRTPVQTIVLSAERRPE
HCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCHH
LVERIRAACAEGRQAYWVCTLIEESEDTDKGAQNGPPRIEAQAAQVTFETLSAQLPGVRV
HHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
ALVHGRMKPAEKQQAMLDFKQGRTDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQ
EEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHH
LRGRVGRGAAASSCVLLYQGPLSLMARQRLETMRQTNDGFVIAERDLELRGPGELLGTRQ
HHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCC
TGLASFRIADLARDAGLLPRVQVLAERLLDEAPEIADRVVARWIGGAVRYAAA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]