Click here to switch to the map view.

The map label for this gene is uppP [H]

Identifier: 66766538

GI number: 66766538

Start: 240872

End: 241663

Strand: Reverse

Name: uppP [H]

Synonym: XC_0193

Alternate gene names: 66766538

Gene position: 241663-240872 (Counterclockwise)

Preceding gene: 66766547

Following gene: 66766537

Centisome position: 4.69

GC content: 64.39

Gene sequence:

>792_bases
ATGTCCGACCTCATTTCCGCCCTGTTGCTGGGCATTCTCGAAGGCCTCACCGAATTTCTGCCGATCTCCAGCACCGGCCA
CCTACTGATCGCCGAACAATGGCTCGGACGCCGCTCGGATTTCTTCAATATCGTCATCCAGGCCGGCGCGATCCTGGCGA
TCTGCCTGGCGCTGCGGCAAAAGCTGTGGACCCTGGCCACCGGCCTGGGCGAGCGCGCCAATCGCGACTACGTGCTCAAG
ATCGGCGTGGCCTTCCTGGTCACGGCGGTGGTCGGCCTGATCGTGCGCAAAGCCGGCTGGCAATTGCCGGAAACCATCCA
GCCGGTGGCCTGGGCGCTGCTGATCGGCGGCGTGTGGATGCTGGTGGCCGAACACTTTGCCGGCAAGCTGCCCGAGCGCG
ACGTGGTCACCTGGAAGGTGGCGATCGCAGTTGGCCTGGCCCAGGTGGTGGCCGGCGTGTTTCCGGGCACCTCGCGCTCG
GCCTCGGCGATTTTCCTGGCCATGCTGCTGGGCCTGAGCAAGCGCTCGGCGGCGGCGGATTTTGTGTTCATGGTCGGCAT
TCCCACCATGTTTGCTGCCAGCGGTTACGCGCTGCTGGAGATGTACAAGGAAGGCGGCTTTGGCAGCGAGAACTGGACCG
ATGTGTCGGTGGCGTTCATTGCGGCCACCCTCACCGGTTTCGTAGTGGTGAAGTGGCTGCTGGGCTACATCAAGAAGCAC
CGCTTCACGGTATTTGCGGTGTACCGCATCCTGCTCGGCGCCGCGCTGCTGCTGTGGTTGCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
TCAACACCACCTTGGTGCTAAGCGAATCCATCGTGCACCAAAATGGTGCATGCCGCAATGCACTATCCTTTCACCTCCCC
CCGCACTCCTCTCCCGCCCG

Downstream 100 bases:

>100_bases
GCCGGCCGATGCCGGGGCAGTGACGGCCGTCATTGCCCCGGCAGCCCGCTGGCGGTATCACTGAGCGGGTCCGCCGCCCG
GGAGCCATCGATGCGTGCCG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQKLWTLATGLGERANRDYVLK
IGVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASAIFLAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKH
RFTVFAVYRILLGAALLLWLPAA

Sequences:

>Translated_263_residues
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQKLWTLATGLGERANRDYVLK
IGVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRS
ASAIFLAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKH
RFTVFAVYRILLGAALLLWLPAA
>Mature_262_residues
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQKLWTLATGLGERANRDYVLKI
GVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWMLVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSA
SAIFLAMLLGLSKRSAAADFVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKHR
FTVFAVYRILLGAALLLWLPAA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin [H]

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family [H]

Homologues:

Organism=Escherichia coli, GI1789437, Length=271, Percent_Identity=35.0553505535055, Blast_Score=128, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003824 [H]

Pfam domain/function: PF02673 BacA [H]

EC number: =3.6.1.27 [H]

Molecular weight: Translated: 28364; Mature: 28233

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KLWTLATGLGERANRDYVLKIGVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWM
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASAIFLAMLLGLSKRSAAAD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHH
FVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKH
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTVFAVYRILLGAALLLWLPAA
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDLISALLLGILEGLTEFLPISSTGHLLIAEQWLGRRSDFFNIVIQAGAILAICLALRQ
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KLWTLATGLGERANRDYVLKIGVAFLVTAVVGLIVRKAGWQLPETIQPVAWALLIGGVWM
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVAEHFAGKLPERDVVTWKVAIAVGLAQVVAGVFPGTSRSASAIFLAMLLGLSKRSAAAD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHH
FVFMVGIPTMFAASGYALLEMYKEGGFGSENWTDVSVAFIAATLTGFVVVKWLLGYIKKH
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTVFAVYRILLGAALLLWLPAA
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]