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The map label for this gene is hutU [H]

Identifier: 66048052

GI number: 66048052

Start: 5730019

End: 5731716

Strand: Direct

Name: hutU [H]

Synonym: Psyr_4828

Alternate gene names: 66048052

Gene position: 5730019-5731716 (Clockwise)

Preceding gene: 66048046

Following gene: 66048053

Centisome position: 94.03

GC content: 63.19

Gene sequence:

>1698_bases
GTGACCGAGAATAATCAACACCTGAAGCAGGACTGGACCCGCCATCGCGAAGGCGTCGTACGGGCTGCACGCGGTACTCA
ATTGACTGCCAAGAGCTGGCTGACCGAAGCGCCGCTACGCATGTTGATGAACAATCTCGACCCGGAAGTCGCCGAAAACC
CCAATGAGCTGGTGGTTTACGGCGGCATCGGCCGCGCCGCGCGCAACTGGGAGTGCTACGACAAGATCGTCGAGAGCCTC
ACTCAGCTCAACGATGATGAAACCCTGCTGGTACAGTCCGGCAAGCCGGTCGGCGTGTTCAAGACCCACAGCAACGCCCC
TCGCGTATTGATCGCCAACTCCAACCTGGTACCGCACTGGGCCAGTTGGGAGCACTTCAACGAACTGGATGCCAAGGGCC
TGGCCATGTATGGCCAGATGACCGCCGGCAGCTGGATCTACATCGGCAGCCAGGGCATCGTGCAAGGCACTTACGAAACC
TTCGTCGAAGCCGGTCGCCAGCACTATGACGGCAACCTCAAGGGCCGCTGGGTGCTCACCGCAGGTCTGGGCGGCATGGG
TGGCGCGCAGCCGCTGGCCGCGACATTGGCCGGGGCCTGCTCGCTGAACATAGAATGCCAGCAGAGCCGCATCGATTTCC
GCATCAAGACCCGCTACGTTGACGAACAGGCCGCAGATCTCGATGACGCACTGGCGCGTATCGCCAAATACACGGCCGAA
GGCAAAGCCATCTCCATCGCGCTGTGTGGCAACGCGGCGGAAATCCTGCCGGAAATGGTCCGTCGCGGTGTGCGCCCGGA
CATGGTCACCGACCAGACCAGCGCCCACGACCCGCTCAATGGTTACCTGCCCAAAGGCTGGACCTGGGACGAGTACCGTG
CCCGTTCGGTGAGCGAACCGGCCAGTGTGGTCAAGGCCGCCAAGCAGTCGATGGCCGAGCACGTCGAAGCCATGCTCGCC
TTCCAGCAAGCCGGCATTCCGACCTTCGACTACGGCAACAATATTCGTCAGATGGCCAAGGAAGTCGGCGTCACCAATGC
CTTCGATTTTCCGGGCTTCGTGCCGGCCTATATCCGTCCGCTGTTCTGCCGTGGCATCGGGCCGTTCCGCTGGGCCGCGC
TGTCGGGCGACCCGCAGGACATCTACAAGACCGACGCCAAAGTCAAAGAGCTGATCCCGGACGACGAGCACCTGCACAAC
TGGCTGGACATGGCCCGCGAGCGCATCAGCTTCCAGGGCCTGCCGGCGCGTATCTGCTGGGTCGGCCTGGGTCAACGCGC
CAGACTGGGTCTGGCCTTCAACGAAATGGTCCGCAGTGGCGAGTTGTCGGCACCGGTGGTGATCGGTCGCGACCACCTGG
ACTCCGGCTCGGTCGCCAGCCCCAACCGCGAAACCGAATCCATGCGTGACGGCTCCGACGCTGTTTCCGACTGGCCGCTG
CTCAATGCTCTGCTCAACACCGCCAGCGGTGCGACCTGGGTCTCGCTGCACCACGGTGGCGGCGTCGGCATGGGCTTCTC
GCAGCATTCCGGGATGGTAATCGTCTGCGACGGCACGGACGAAGCCGCCGAGCGTATTGCCCGCGTGCTGCATAACGACC
CGGCCACCGGGGTGATGCGCCATGCCGATGCCGGTTACGACATCGCTATCGACTGTGCCAGAGAGCAGGGCTTGAACCTG
CCAATGATCGGACGTTGA

Upstream 100 bases:

>100_bases
GCTAAACATTCCGCCTTCTACCCAACTGAATCGGCCTGCTTCGCCAGGCTTTGCTCGCCCTTCATCGGGCTGGTTCGAAT
TGATCGCCGAGGATTTTTTT

Downstream 100 bases:

>100_bases
CAACGTTGTCGGCCATCAGGCCGGCACACGTCGGGGACGGGCATGAGCATGCCCACGGGCCGGATGCCTACTTGAAGCTG
CCGTCATCCATTTAAGGCTT

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MTENNQHLKQDWTRHREGVVRAARGTQLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVYGGIGRAARNWECYDKIVESL
TQLNDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWASWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYET
FVEAGRQHYDGNLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRIKTRYVDEQAADLDDALARIAKYTAE
GKAISIALCGNAAEILPEMVRRGVRPDMVTDQTSAHDPLNGYLPKGWTWDEYRARSVSEPASVVKAAKQSMAEHVEAMLA
FQQAGIPTFDYGNNIRQMAKEVGVTNAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDEHLHN
WLDMARERISFQGLPARICWVGLGQRARLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETESMRDGSDAVSDWPL
LNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGVMRHADAGYDIAIDCAREQGLNL
PMIGR

Sequences:

>Translated_565_residues
MTENNQHLKQDWTRHREGVVRAARGTQLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVYGGIGRAARNWECYDKIVESL
TQLNDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWASWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYET
FVEAGRQHYDGNLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRIKTRYVDEQAADLDDALARIAKYTAE
GKAISIALCGNAAEILPEMVRRGVRPDMVTDQTSAHDPLNGYLPKGWTWDEYRARSVSEPASVVKAAKQSMAEHVEAMLA
FQQAGIPTFDYGNNIRQMAKEVGVTNAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDEHLHN
WLDMARERISFQGLPARICWVGLGQRARLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETESMRDGSDAVSDWPL
LNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGVMRHADAGYDIAIDCAREQGLNL
PMIGR
>Mature_564_residues
TENNQHLKQDWTRHREGVVRAARGTQLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVYGGIGRAARNWECYDKIVESLT
QLNDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWASWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETF
VEAGRQHYDGNLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRIKTRYVDEQAADLDDALARIAKYTAEG
KAISIALCGNAAEILPEMVRRGVRPDMVTDQTSAHDPLNGYLPKGWTWDEYRARSVSEPASVVKAAKQSMAEHVEAMLAF
QQAGIPTFDYGNNIRQMAKEVGVTNAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDEHLHNW
LDMARERISFQGLPARICWVGLGQRARLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETESMRDGSDAVSDWPLL
NALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGVMRHADAGYDIAIDCAREQGLNLP
MIGR

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=569, Percent_Identity=33.5676625659051, Blast_Score=302, Evalue=6e-82,
Organism=Homo sapiens, GI260306182, Length=216, Percent_Identity=37.962962962963, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71997891, Length=533, Percent_Identity=34.7091932457786, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 61881; Mature: 61749

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENNQHLKQDWTRHREGVVRAARGTQLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVY
CCCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GGIGRAARNWECYDKIVESLTQLNDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHW
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCC
ASWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGNLKGRWVLT
CCHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
AGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRIKTRYVDEQAADLDDALARIAKYTAE
ECCCCCCCCHHHHHHHHHHHEECEEEECCCCCEEEEEEECCHHHCCHHHHHHHHHHHCCC
GKAISIALCGNAAEILPEMVRRGVRPDMVTDQTSAHDPLNGYLPKGWTWDEYRARSVSEP
CCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCH
ASVVKAAKQSMAEHVEAMLAFQQAGIPTFDYGNNIRQMAKEVGVTNAFDFPGFVPAYIRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDEHLHNWLDMARERISFQGLPARICW
HHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VGLGQRARLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETESMRDGSDAVSDWPL
EECCCHHEECHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
LNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGVMR
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHH
HADAGYDIAIDCAREQGLNLPMIGR
HCCCCCEEEEEEHHHCCCCCCCCCC
>Mature Secondary Structure 
TENNQHLKQDWTRHREGVVRAARGTQLTAKSWLTEAPLRMLMNNLDPEVAENPNELVVY
CCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GGIGRAARNWECYDKIVESLTQLNDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHW
CCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCC
ASWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYDGNLKGRWVLT
CCHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
AGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRIKTRYVDEQAADLDDALARIAKYTAE
ECCCCCCCCHHHHHHHHHHHEECEEEECCCCCEEEEEEECCHHHCCHHHHHHHHHHHCCC
GKAISIALCGNAAEILPEMVRRGVRPDMVTDQTSAHDPLNGYLPKGWTWDEYRARSVSEP
CCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCH
ASVVKAAKQSMAEHVEAMLAFQQAGIPTFDYGNNIRQMAKEVGVTNAFDFPGFVPAYIRP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LFCRGIGPFRWAALSGDPQDIYKTDAKVKELIPDDEHLHNWLDMARERISFQGLPARICW
HHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
VGLGQRARLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETESMRDGSDAVSDWPL
EECCCHHEECHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
LNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLHNDPATGVMR
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHH
HADAGYDIAIDCAREQGLNLPMIGR
HCCCCCEEEEEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA