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The map label for this gene is ltaE [H]

Identifier: 66047990

GI number: 66047990

Start: 5641228

End: 5642268

Strand: Direct

Name: ltaE [H]

Synonym: Psyr_4766

Alternate gene names: 66047990

Gene position: 5641228-5642268 (Clockwise)

Preceding gene: 66047988

Following gene: 66047991

Centisome position: 92.57

GC content: 60.9

Gene sequence:

>1041_bases
ATGACAGACCAAAGCCAACAGTTCGCCAGCGACAACTATTCCGGTATCTGCCCTGAAGCCTGGGCAGCCATGGAGCAGGC
GAACAAGGGCCATCAACGCGCTTATGGTGACGATCAATGGACTGCCCGCGCTTCGGATGATTTCCGCCGACTGTTCGAAA
CCGACTGCGAAGTGTTTTTCGCCTTCAACGGCACGGCGGCCAACTCGCTGGCACTGTCATCGCTGTGCCAGAGTTACCAC
AGTGTCATCTGTTCGGAAACGGCTCACGTCGAAACCGATGAATGCGGTGCGCCGGAGTTTTTCTCCAACGGTTCCAAACT
GCTGACAGCCCGCAGCGCGGGCGGCAAGCTGACCCCGGAATCGATTCGTGAAGTGGCGCTCAAGCGTCAGGACATTCACT
ACCCCAAGCCGCGCGTCGTGACCCTCACCCAGGCCACCGAGGTGGGCGGCGTCTATCAGCCGGAAGAACTCAAGGCAATC
AGCGCGACCTGCAAGGAACTGGGCCTGCACCTGCACATGGACGGTGCCCGCTTCTCCAATGCCTGCGCCTTTCTGGAGGC
TTCCCCGGCTGAACTGACCTGGAAGTCCGGCGTTGACGTGTTGTGCTTCGGCGGCACCAAAAACGGTATGGCGGTGGGCG
AAGCGATTCTGTTTTTCGACCATGATCTGGCTGAAGACTTCGACTATCGCTGCAAGCAGGCCGGGCAACTGGCGTCGAAG
ATGCGCTTCCTGTCTGCACCGTGGGTCGGCCTGCTGGAAAACGACGCCTGGCTCAAACACGCCCGTCACGCCAACCGCTG
TGCGCAACTGCTCGCCGAACTGGTCAAGGACATTCCTGGCGTGGAGCTGATGTTCCCGGTGCAGGCCAATGGCGTGTTCC
TGCAGCTGTCGGAGCCGGCCATTGCTGCATTGACCGCCCGCGGCTGGCGCTTCTACACCTTCATCGGCAACGGCGGCGCC
CGTTTCATGTGCTCGTGGGACACCGAAGAAGACCGCGTGCGTGAACTGGCCGCCGATATCAGGCTGGTGATGCAGGGCTG
A

Upstream 100 bases:

>100_bases
TAGTGCTCCTGAACGGGGAATTGCGTCATGCAGCCAACACATGACCGAACCTTATATTGTCGCTACAGTGCGCACCATAA
TCGCCCATAAGGAATCGGCC

Downstream 100 bases:

>100_bases
AGCGTCTAAATCAAGCTTGCAGGTGCAGCCTGACGAGCGACGGGTTAATCTCCTTCTTGACGGCAAACGGCCCACAAGGC
CGTCCGGACTTTACCGACCG

Product: threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTDQSQQFASDNYSGICPEAWAAMEQANKGHQRAYGDDQWTARASDDFRRLFETDCEVFFAFNGTAANSLALSSLCQSYH
SVICSETAHVETDECGAPEFFSNGSKLLTARSAGGKLTPESIREVALKRQDIHYPKPRVVTLTQATEVGGVYQPEELKAI
SATCKELGLHLHMDGARFSNACAFLEASPAELTWKSGVDVLCFGGTKNGMAVGEAILFFDHDLAEDFDYRCKQAGQLASK
MRFLSAPWVGLLENDAWLKHARHANRCAQLLAELVKDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGNGGA
RFMCSWDTEEDRVRELAADIRLVMQG

Sequences:

>Translated_346_residues
MTDQSQQFASDNYSGICPEAWAAMEQANKGHQRAYGDDQWTARASDDFRRLFETDCEVFFAFNGTAANSLALSSLCQSYH
SVICSETAHVETDECGAPEFFSNGSKLLTARSAGGKLTPESIREVALKRQDIHYPKPRVVTLTQATEVGGVYQPEELKAI
SATCKELGLHLHMDGARFSNACAFLEASPAELTWKSGVDVLCFGGTKNGMAVGEAILFFDHDLAEDFDYRCKQAGQLASK
MRFLSAPWVGLLENDAWLKHARHANRCAQLLAELVKDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGNGGA
RFMCSWDTEEDRVRELAADIRLVMQG
>Mature_345_residues
TDQSQQFASDNYSGICPEAWAAMEQANKGHQRAYGDDQWTARASDDFRRLFETDCEVFFAFNGTAANSLALSSLCQSYHS
VICSETAHVETDECGAPEFFSNGSKLLTARSAGGKLTPESIREVALKRQDIHYPKPRVVTLTQATEVGGVYQPEELKAIS
ATCKELGLHLHMDGARFSNACAFLEASPAELTWKSGVDVLCFGGTKNGMAVGEAILFFDHDLAEDFDYRCKQAGQLASKM
RFLSAPWVGLLENDAWLKHARHANRCAQLLAELVKDIPGVELMFPVQANGVFLQLSEPAIAALTARGWRFYTFIGNGGAR
FMCSWDTEEDRVRELAADIRLVMQG

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=329, Percent_Identity=26.7477203647416, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38145; Mature: 38014

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQSQQFASDNYSGICPEAWAAMEQANKGHQRAYGDDQWTARASDDFRRLFETDCEVFF
CCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEE
AFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLTARSAGGKLTPE
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHH
SIREVALKRQDIHYPKPRVVTLTQATEVGGVYQPEELKAISATCKELGLHLHMDGARFSN
HHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
ACAFLEASPAELTWKSGVDVLCFGGTKNGMAVGEAILFFDHDLAEDFDYRCKQAGQLASK
CEEEEECCCCCEECCCCCCEEEECCCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHH
MRFLSAPWVGLLENDAWLKHARHANRCAQLLAELVKDIPGVELMFPVQANGVFLQLSEPA
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCC
IAALTARGWRFYTFIGNGGARFMCSWDTEEDRVRELAADIRLVMQG
EEEEEECCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
TDQSQQFASDNYSGICPEAWAAMEQANKGHQRAYGDDQWTARASDDFRRLFETDCEVFF
CCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEE
AFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLTARSAGGKLTPE
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCHH
SIREVALKRQDIHYPKPRVVTLTQATEVGGVYQPEELKAISATCKELGLHLHMDGARFSN
HHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
ACAFLEASPAELTWKSGVDVLCFGGTKNGMAVGEAILFFDHDLAEDFDYRCKQAGQLASK
CEEEEECCCCCEECCCCCCEEEECCCCCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHH
MRFLSAPWVGLLENDAWLKHARHANRCAQLLAELVKDIPGVELMFPVQANGVFLQLSEPA
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCC
IAALTARGWRFYTFIGNGGARFMCSWDTEEDRVRELAADIRLVMQG
EEEEEECCEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]