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The map label for this gene is coaD [H]

Identifier: 66047982

GI number: 66047982

Start: 5634887

End: 5635366

Strand: Direct

Name: coaD [H]

Synonym: Psyr_4758

Alternate gene names: 66047982

Gene position: 5634887-5635366 (Clockwise)

Preceding gene: 66047979

Following gene: 66047983

Centisome position: 92.47

GC content: 58.13

Gene sequence:

>480_bases
ATGAACCGAGTGTTGTACCCAGGCACCTTCGACCCGATTACCAAGGGCCATGGAGATCTGGTCGAGCGCGCCTCGCGCCT
GTTCGACCAAGTGGTCATTGCGGTTGCCGCCAGCCCGAAGAAAAACCCGCTGTTCCCTCTGGAGCAACGCGTCGAGCTGG
CCCGCGAAGTCACCAAGCACTTGCCCAATGTGGAAGTGGTCGGTTTTTCGACCCTGCTGGCGCATTTTGCCAAGGAACAG
AATGCCAATGTCTTTCTGCGCGGACTTCGTGCCGTCTCGGACTTCGAATACGAGTTTCAGTTGGCCAACATGAATCGTCA
GCTGGCACCGGACGTCGAAAGCCTGTTCCTCACGCCGTCGGAGCGCTACTCGTTCATTTCCTCGACGTTAGTGCGTGAAA
TCGCCGCGTTGGGCGGTGATATCACCAAGTTCGTTCACCCTGCAGTTGCCCAGGCGCTGACCGAACGCTTCAAGCGCTAG

Upstream 100 bases:

>100_bases
CGGCGCAATACGACGTTTGATACCTGCCGCACAGCTTGGCCCATCGGGAAGGCTGCGATACCATCCGAGTCCCACAACGG
ACTCCGACCAGGACGACGCG

Downstream 100 bases:

>100_bases
ACGCGCTGCATGTGAAGGTGCATCCCGAAGCCTAATGCGGCACAATTCGCCGCATTGGTTTTAATGTGCCCCGGCGTCGG
CCGCGGCAGGAGCAATTCAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVVGFSTLLAHFAKEQ
NANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR

Sequences:

>Translated_159_residues
MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVVGFSTLLAHFAKEQ
NANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR
>Mature_159_residues
MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKHLPNVEVVGFSTLLAHFAKEQ
NANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=60, Blast_Score=202, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17856; Mature: 17856

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LPNVEVVGFSTLLAHFAKEQNANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPS
CCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHCCCH
ERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRVLYPGTFDPITKGHGDLVERASRLFDQVVIAVAASPKKNPLFPLEQRVELAREVTKH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LPNVEVVGFSTLLAHFAKEQNANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPS
CCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHCCCH
ERYSFISSTLVREIAALGGDITKFVHPAVAQALTERFKR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]