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The map label for this gene is pqqL [C]

Identifier: 66047976

GI number: 66047976

Start: 5628208

End: 5629560

Strand: Direct

Name: pqqL [C]

Synonym: Psyr_4752

Alternate gene names: 66047976

Gene position: 5628208-5629560 (Clockwise)

Preceding gene: 66047971

Following gene: 66047977

Centisome position: 92.36

GC content: 60.98

Gene sequence:

>1353_bases
ATGAATGCTTTAGCCCGCCGCGCCGCAGGCCTGCTGCTCAGCACAATTTGTCTGCCTTTGACAGCATTGGCTGCCGATCC
GCAACCGACTCACGAATTCACCCTCGACAATGGCCTGAAAGTTGTTGTCCGCGAAGACCACCGCGCTCCGGTGGTGGTTT
CGCAGATCTGGTACAAGGTCGGCTCCAGCTACGAAACGCCGGGACAGACCGGTCTGTCCCACGCACTTGAACACATGATG
TTCAAAGGCAGCAGCAAAACCGGACCGGGCGAGTCTTCGCTGATTCTGCGCGATCTGGGCGCTGAAGAGAATGCGTTCAC
CAGCGACGACTACACCGCCTATTACCAGGTACTGGCGCGTGACCGCCTGAGCGTCGCGCTGGAGCTGGAAGCCGATCGCA
TGGCAACCCTGAAATTGCCCGCCGACGAGTTCAGCCGCGAGATCGAGGTCATCAAGGAGGAACGTCGCCTGCGTACCGAT
GACCAGCCAATGGGCAAGGCGTTCGAGCGCTTCAAGGCGATGGCCTACCCTGCCAGCGGCTATCACACGCCGACCATCGG
CTGGATGGCGGACCTGGAGCGCATGAAGGTCGAAGAACTGCGCCACTGGTACGAATCCTGGTATGCGCCGAACAACGCCA
CGCTGGTGGTGGTCGGCGATGTGCTGCCGGACGACGTCAAAGCCCTGGCAGAACGCTTCTTCGGATCGATCCCGCGCCGC
GCTGTACCGCCTTCGAAAAAACCGCTTGAACTGGCCGAACCTGGCGAGCGCAAGATCACCCTGCACGTCAAAACCCAGTT
GCCGAGCCTGATCTACGGCTTCAACGTACCGAGTGTCGCAACCGCTGAAGATCCACGTTCGGCGAACGCCCTGCGCCTTA
TCGCAGCGCTGCTCGACGGTGGTTACAGCGCACGCATTCCCGCACGCCTGGAACGTGGCGAAGAGCTGGTCTCCGGTGCC
TCGTCGCGTTACGACGCGTTCGCTCGCGGCGACAGCCTGTTCATGATCAGCGCCACACCCAACCAGCAGAAGAAGAAAAC
CCTGGCCGATGTGGAAGCCGGGATCTGGCGCCTGCTCGATGAGCTGAAAACCAAGGCACCGTCCGCCGAGGAGCTGGAGC
GTGTCCGGGCTCAGGTCATTGCCGGTGTGGTCTATGAGCGCGACTCGATCACCAGCCAGGCGACCATGATCGGAGAGCTG
GAAACCGTCGGTCTGTCCTGGAAGCTGATGGACAATGAACTGGAGGCGCTGCAGAGCGTGACCCCGCAAGACATCCAGAA
AGCTGCCAACACCTATTTCACCCGTGAGCGCCTCAGCGTTGCGCACGTTCTGCCTGAGGAGAAAGCCAAATGA

Upstream 100 bases:

>100_bases
CAGTGAAGGCTGTCTCTGAAGCAAACGGATCAGTATCCTAACACCCCCGCGCCCGCCGACGCTAAGTTCACGCGGGCCGT
CCTACAGGTTCAAACTACGA

Downstream 100 bases:

>100_bases
TCACGCGCAATGCTCCACGTCATGCGCTGCTTGGCCTGATCCTGGCCGGTTCGCTCGGTGCCTTTTTCGCACTGCCGGCC
CTGGCCGACGACGCCCCTGC

Product: insulinase-like:peptidase M16, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNALARRAAGLLLSTICLPLTALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQIWYKVGSSYETPGQTGLSHALEHMM
FKGSSKTGPGESSLILRDLGAEENAFTSDDYTAYYQVLARDRLSVALELEADRMATLKLPADEFSREIEVIKEERRLRTD
DQPMGKAFERFKAMAYPASGYHTPTIGWMADLERMKVEELRHWYESWYAPNNATLVVVGDVLPDDVKALAERFFGSIPRR
AVPPSKKPLELAEPGERKITLHVKTQLPSLIYGFNVPSVATAEDPRSANALRLIAALLDGGYSARIPARLERGEELVSGA
SSRYDAFARGDSLFMISATPNQQKKKTLADVEAGIWRLLDELKTKAPSAEELERVRAQVIAGVVYERDSITSQATMIGEL
ETVGLSWKLMDNELEALQSVTPQDIQKAANTYFTRERLSVAHVLPEEKAK

Sequences:

>Translated_450_residues
MNALARRAAGLLLSTICLPLTALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQIWYKVGSSYETPGQTGLSHALEHMM
FKGSSKTGPGESSLILRDLGAEENAFTSDDYTAYYQVLARDRLSVALELEADRMATLKLPADEFSREIEVIKEERRLRTD
DQPMGKAFERFKAMAYPASGYHTPTIGWMADLERMKVEELRHWYESWYAPNNATLVVVGDVLPDDVKALAERFFGSIPRR
AVPPSKKPLELAEPGERKITLHVKTQLPSLIYGFNVPSVATAEDPRSANALRLIAALLDGGYSARIPARLERGEELVSGA
SSRYDAFARGDSLFMISATPNQQKKKTLADVEAGIWRLLDELKTKAPSAEELERVRAQVIAGVVYERDSITSQATMIGEL
ETVGLSWKLMDNELEALQSVTPQDIQKAANTYFTRERLSVAHVLPEEKAK
>Mature_450_residues
MNALARRAAGLLLSTICLPLTALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQIWYKVGSSYETPGQTGLSHALEHMM
FKGSSKTGPGESSLILRDLGAEENAFTSDDYTAYYQVLARDRLSVALELEADRMATLKLPADEFSREIEVIKEERRLRTD
DQPMGKAFERFKAMAYPASGYHTPTIGWMADLERMKVEELRHWYESWYAPNNATLVVVGDVLPDDVKALAERFFGSIPRR
AVPPSKKPLELAEPGERKITLHVKTQLPSLIYGFNVPSVATAEDPRSANALRLIAALLDGGYSARIPARLERGEELVSGA
SSRYDAFARGDSLFMISATPNQQKKKTLADVEAGIWRLLDELKTKAPSAEELERVRAQVIAGVVYERDSITSQATMIGEL
ETVGLSWKLMDNELEALQSVTPQDIQKAANTYFTRERLSVAHVLPEEKAK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=222, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI46593007, Length=207, Percent_Identity=28.9855072463768, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI155969707, Length=228, Percent_Identity=27.6315789473684, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787770, Length=371, Percent_Identity=26.4150943396226, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367164, Length=345, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=225, Percent_Identity=27.1111111111111, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=224, Percent_Identity=24.1071428571429, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=428, Percent_Identity=21.7289719626168, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323421, Length=346, Percent_Identity=21.3872832369942, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=219, Percent_Identity=29.6803652968037, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646943, Length=219, Percent_Identity=29.6803652968037, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49943; Mature: 49943

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALARRAAGLLLSTICLPLTALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQIWYKV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHH
GSSYETPGQTGLSHALEHMMFKGSSKTGPGESSLILRDLGAEENAFTSDDYTAYYQVLAR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
DRLSVALELEADRMATLKLPADEFSREIEVIKEERRLRTDDQPMGKAFERFKAMAYPASG
HHHEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
YHTPTIGWMADLERMKVEELRHWYESWYAPNNATLVVVGDVLPDDVKALAERFFGSIPRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
AVPPSKKPLELAEPGERKITLHVKTQLPSLIYGFNVPSVATAEDPRSANALRLIAALLDG
CCCCCCCCCCCCCCCCEEEEEEEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
GYSARIPARLERGEELVSGASSRYDAFARGDSLFMISATPNQQKKKTLADVEAGIWRLLD
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
ELKTKAPSAEELERVRAQVIAGVVYERDSITSQATMIGELETVGLSWKLMDNELEALQSV
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHCC
TPQDIQKAANTYFTRERLSVAHVLPEEKAK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNALARRAAGLLLSTICLPLTALAADPQPTHEFTLDNGLKVVVREDHRAPVVVSQIWYKV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHHH
GSSYETPGQTGLSHALEHMMFKGSSKTGPGESSLILRDLGAEENAFTSDDYTAYYQVLAR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
DRLSVALELEADRMATLKLPADEFSREIEVIKEERRLRTDDQPMGKAFERFKAMAYPASG
HHHEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
YHTPTIGWMADLERMKVEELRHWYESWYAPNNATLVVVGDVLPDDVKALAERFFGSIPRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
AVPPSKKPLELAEPGERKITLHVKTQLPSLIYGFNVPSVATAEDPRSANALRLIAALLDG
CCCCCCCCCCCCCCCCEEEEEEEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
GYSARIPARLERGEELVSGASSRYDAFARGDSLFMISATPNQQKKKTLADVEAGIWRLLD
CCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
ELKTKAPSAEELERVRAQVIAGVVYERDSITSQATMIGELETVGLSWKLMDNELEALQSV
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHCC
TPQDIQKAANTYFTRERLSVAHVLPEEKAK
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]