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The map label for this gene is ribD [H]

Identifier: 66047689

GI number: 66047689

Start: 5324768

End: 5325868

Strand: Reverse

Name: ribD [H]

Synonym: Psyr_4462

Alternate gene names: 66047689

Gene position: 5325868-5324768 (Counterclockwise)

Preceding gene: 161486727

Following gene: 66047688

Centisome position: 87.4

GC content: 66.49

Gene sequence:

>1101_bases
ATGGCGCGAGCACTCGAGCTGGCGCGCAAGGGGCTGTACTCCACGCATCCCAACCCGCGAGTCGGCTGCGTGATCGTGCG
TGAAGGCCGGATCGTTGGCGAAGGCTGGCATGCGCGCGCCGGTGAACCGCATGCCGAAGTGCATGCCTTGCGCCAGGCCG
GCGAGCTGGCCAGAGGCGCGACCGCCTACGTCACCCTCGAGCCGTGCAGTCACCAGGGGCGCACACCGCCCTGTGCCGAT
GCACTGATCGAAGCCGGGCTGACGCGGGTTGTCGCAGCGATGCAGGACCCCAACCCCGAAGTTTCCGGTCGCGGCCTGTT
GCGCCTCATGAATGCCGGCATCGGCGTTCAGTGTGGTGTGCTGGAAAGCGAAGCGCGAGCGCTGAACAAAGGCTTTCTCA
AGCGCATGGAGACCGGCCTGCCGTATGTGCGGGTCAAAATGGCCATGAGCCTGGATGGCCGAACGGCGATGGCCAGCGGG
GAAAGCCAGTGGATCACCGGCCCCGAGGCGCGCTCTGCCGTACAGCGCCTGCGCGCCCAGTCGAGCGTGGTGCTCAGCGG
TGCCGACACGGTGCTGGCCGACAAGGCTCGTCTCACCGTACGCCCTGATGAACTGGGGCTCGATGCCGAATTGACCGCGC
TGGCCGCGGCACGCGCGCCGTTGCGCGTGTTGATCGACGGCCGTTTGCGTGTGCCGCTCGATGCACCGTTCTTCCAGGCA
GGCAGTGCGCTGGTCGTGACCTGCGCTGCTGCGTCGGCGCGAGGCCGCTATCAGGAGGAGGGCCACGAAATGCTCGCGCT
GGCCGACAGCGCCGGTCATGTGGACCTGCGCAGGTTGATGGACGAACTCGCAGCGCGGGGCGTCAATGAAGTGCTGGTCG
AGGCCGGTCCGCGACTGGCGGGGGCTTTTGCGCGGCTCGGGCTGGTCGACGAGTTTCAGCTCTTCATTGCCGGCAAGTTT
CTCGGCTCATCGGCCCGTCCGCTGCTCGATCTGCCACTGGCGCAGATGAGCGAGGCACTGGAACTGAACATTGTGGAAAT
GCGTGCTGTCGGTAATGACTGGCGAGTCATCGCTCTCCCTGTGCGCACACCCGGCGTATAA

Upstream 100 bases:

>100_bases
ACCTCAACGAATTCCGTGAAGAAATCGATCGTCTGGCCCGCGAGCCGGGCAAGGAATAAATGCATTGCTGACTGAACAGG
CGGCTCTCGACGTTCATTAC

Downstream 100 bases:

>100_bases
TTCCCGGCTTTCGCCTTGCGCGCAGCCCTTGTTCTCCCGGAGGACCCATGTTTACCGGCATTATCGAATCCATTGGCAGC
ATCCGCGCCCTGACTCCCAA

Product: riboflavin biosynthesis protein RibD:riboflavin-specific deaminase, C-terminal

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MARALELARKGLYSTHPNPRVGCVIVREGRIVGEGWHARAGEPHAEVHALRQAGELARGATAYVTLEPCSHQGRTPPCAD
ALIEAGLTRVVAAMQDPNPEVSGRGLLRLMNAGIGVQCGVLESEARALNKGFLKRMETGLPYVRVKMAMSLDGRTAMASG
ESQWITGPEARSAVQRLRAQSSVVLSGADTVLADKARLTVRPDELGLDAELTALAAARAPLRVLIDGRLRVPLDAPFFQA
GSALVVTCAAASARGRYQEEGHEMLALADSAGHVDLRRLMDELAARGVNEVLVEAGPRLAGAFARLGLVDEFQLFIAGKF
LGSSARPLLDLPLAQMSEALELNIVEMRAVGNDWRVIALPVRTPGV

Sequences:

>Translated_366_residues
MARALELARKGLYSTHPNPRVGCVIVREGRIVGEGWHARAGEPHAEVHALRQAGELARGATAYVTLEPCSHQGRTPPCAD
ALIEAGLTRVVAAMQDPNPEVSGRGLLRLMNAGIGVQCGVLESEARALNKGFLKRMETGLPYVRVKMAMSLDGRTAMASG
ESQWITGPEARSAVQRLRAQSSVVLSGADTVLADKARLTVRPDELGLDAELTALAAARAPLRVLIDGRLRVPLDAPFFQA
GSALVVTCAAASARGRYQEEGHEMLALADSAGHVDLRRLMDELAARGVNEVLVEAGPRLAGAFARLGLVDEFQLFIAGKF
LGSSARPLLDLPLAQMSEALELNIVEMRAVGNDWRVIALPVRTPGV
>Mature_365_residues
ARALELARKGLYSTHPNPRVGCVIVREGRIVGEGWHARAGEPHAEVHALRQAGELARGATAYVTLEPCSHQGRTPPCADA
LIEAGLTRVVAAMQDPNPEVSGRGLLRLMNAGIGVQCGVLESEARALNKGFLKRMETGLPYVRVKMAMSLDGRTAMASGE
SQWITGPEARSAVQRLRAQSSVVLSGADTVLADKARLTVRPDELGLDAELTALAAARAPLRVLIDGRLRVPLDAPFFQAG
SALVVTCAAASARGRYQEEGHEMLALADSAGHVDLRRLMDELAARGVNEVLVEAGPRLAGAFARLGLVDEFQLFIAGKFL
GSSARPLLDLPLAQMSEALELNIVEMRAVGNDWRVIALPVRTPGV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=358, Percent_Identity=56.7039106145251, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI145693172, Length=147, Percent_Identity=35.3741496598639, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38989; Mature: 38857

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARALELARKGLYSTHPNPRVGCVIVREGRIVGEGWHARAGEPHAEVHALRQAGELARGA
CCHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
TAYVTLEPCSHQGRTPPCADALIEAGLTRVVAAMQDPNPEVSGRGLLRLMNAGIGVQCGV
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECC
LESEARALNKGFLKRMETGLPYVRVKMAMSLDGRTAMASGESQWITGPEARSAVQRLRAQ
CHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHC
SSVVLSGADTVLADKARLTVRPDELGLDAELTALAAARAPLRVLIDGRLRVPLDAPFFQA
CCEEEECCCEEEECCCEEEECCHHHCCCHHHHHHHHHCCCEEEEECCEEECCCCCCHHHC
GSALVVTCAAASARGRYQEEGHEMLALADSAGHVDLRRLMDELAARGVNEVLVEAGPRLA
CCEEEEEEEHHHHCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHH
GAFARLGLVDEFQLFIAGKFLGSSARPLLDLPLAQMSEALELNIVEMRAVGNDWRVIALP
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHEEEEEEEECCCCCEEEEEE
VRTPGV
CCCCCC
>Mature Secondary Structure 
ARALELARKGLYSTHPNPRVGCVIVREGRIVGEGWHARAGEPHAEVHALRQAGELARGA
CHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
TAYVTLEPCSHQGRTPPCADALIEAGLTRVVAAMQDPNPEVSGRGLLRLMNAGIGVQCGV
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEECC
LESEARALNKGFLKRMETGLPYVRVKMAMSLDGRTAMASGESQWITGPEARSAVQRLRAQ
CHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHC
SSVVLSGADTVLADKARLTVRPDELGLDAELTALAAARAPLRVLIDGRLRVPLDAPFFQA
CCEEEECCCEEEECCCEEEECCHHHCCCHHHHHHHHHCCCEEEEECCEEECCCCCCHHHC
GSALVVTCAAASARGRYQEEGHEMLALADSAGHVDLRRLMDELAARGVNEVLVEAGPRLA
CCEEEEEEEHHHHCCCCHHCCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHH
GAFARLGLVDEFQLFIAGKFLGSSARPLLDLPLAQMSEALELNIVEMRAVGNDWRVIALP
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHEEEEEEEECCCCCEEEEEE
VRTPGV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]