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The map label for this gene is ribB [H]

Identifier: 66047687

GI number: 66047687

Start: 5322945

End: 5324036

Strand: Reverse

Name: ribB [H]

Synonym: Psyr_4460

Alternate gene names: 66047687

Gene position: 5324036-5322945 (Counterclockwise)

Preceding gene: 66047688

Following gene: 66047686

Centisome position: 87.37

GC content: 62.27

Gene sequence:

>1092_bases
GTGGCGCTCAACAGTATCGAAGAACTGGTCGAAGACATTCGCCAGGGCAAGATGGTCATCCTCATGGATGACGAAGACCG
CGAAAACGAAGGCGACCTGATCATGGCCGCCGAATGCGTGAAGCCCGAGCACATCAACTTCATGGCGCGTTTCGCCCGTG
GTCTGATCTGCATGCCGATGACTCGCGAGCGCTGCGAAACCCTCAAGCTGCCGCTGATGGCAGCGCGCAACGGCTCGGGT
TTCGGCACCAAGTTCACCGTTTCCATCGAAGCCGCCGAAGGCGTGACCACCGGCATCTCGGCAGCCGACCGTGCACGCAC
GGTGCAGGCCGCCGCGGCCAAGGACGCCAAGGCCGAAGACATCGTCAGCCCTGGGCATATCTTCCCGCTCATGGCTCAGG
CGGGCGGCACCCTGGCGCGCGCCGGTCATACCGAAGCGGCCTGCGACCTGGCGCGCATGGCCGGTTTCGAGCCGACGGGC
CTGATCTGCGAAGTCATGAACGACGACGGCACCATGTCGCGTCGCGCCGAACTCGAAGCATTTGCCCTGCAACATGACAT
CAAGATCGGCACCATCGCCGACCTGATTCACTACCGGATGATCCACGAACGTACCGTTCAGCGGATTGCCGAGCAGCCGA
TGGACAGCGAACTGGGCAGTTTCAACCTGGTGACCTACCGCGATTCGGTCGAGGGCGACGTGCATCTGGCGCTGACCCTG
GGCACCATCTGTGCCGAAGAGCCCACGCTGGTTCGCGTGCACAACATGGACCCGCTGCGTGACCTGTTGATGGTCAACCA
GCCCGGCCGCTGGAGCCTGCGCGCCGCCATGCGCGCGGTTAACGAGGCGGGCAGCGGTGTGGTGCTGCTGCTCGGTCACC
CGCTGGATGGCGATGTCTTGCTGGCACATATTCGCGAAACCGCCGGTCAGCAACCGATCAAGACGCCGACTACGTACAGC
ACGGTCGGTGCCGGTTCGCAGATCCTTCGTGACCTCGGTGTGCGCAAAATGCGCCTGATGAGTTCGCCGATGAAGTTCAA
TGCGATATCCGGTTTCGATCTGGAAGTTGTAGAATACGTGCCCTCCGAATAA

Upstream 100 bases:

>100_bases
GGGTGACAAGGCCGCCGAGCCGGGCCACGGCACGATCACCGAAAGCTTCCTGGCCGAGAACGGCTACCTCAAATCCTGAA
TTGATTGAAGGGGGTGCCGC

Downstream 100 bases:

>100_bases
ATACCGGCAGGTCGGGGCGTGTGAAAGATGGTTTTTCGCAGGTTTTGGCCTGACAGGCATGATTCGTGGCCTAATATCCC
TCAAAGTCCGCCCCAAGGCG

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MALNSIEELVEDIRQGKMVILMDDEDRENEGDLIMAAECVKPEHINFMARFARGLICMPMTRERCETLKLPLMAARNGSG
FGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKDAKAEDIVSPGHIFPLMAQAGGTLARAGHTEAACDLARMAGFEPTG
LICEVMNDDGTMSRRAELEAFALQHDIKIGTIADLIHYRMIHERTVQRIAEQPMDSELGSFNLVTYRDSVEGDVHLALTL
GTICAEEPTLVRVHNMDPLRDLLMVNQPGRWSLRAAMRAVNEAGSGVVLLLGHPLDGDVLLAHIRETAGQQPIKTPTTYS
TVGAGSQILRDLGVRKMRLMSSPMKFNAISGFDLEVVEYVPSE

Sequences:

>Translated_363_residues
MALNSIEELVEDIRQGKMVILMDDEDRENEGDLIMAAECVKPEHINFMARFARGLICMPMTRERCETLKLPLMAARNGSG
FGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKDAKAEDIVSPGHIFPLMAQAGGTLARAGHTEAACDLARMAGFEPTG
LICEVMNDDGTMSRRAELEAFALQHDIKIGTIADLIHYRMIHERTVQRIAEQPMDSELGSFNLVTYRDSVEGDVHLALTL
GTICAEEPTLVRVHNMDPLRDLLMVNQPGRWSLRAAMRAVNEAGSGVVLLLGHPLDGDVLLAHIRETAGQQPIKTPTTYS
TVGAGSQILRDLGVRKMRLMSSPMKFNAISGFDLEVVEYVPSE
>Mature_362_residues
ALNSIEELVEDIRQGKMVILMDDEDRENEGDLIMAAECVKPEHINFMARFARGLICMPMTRERCETLKLPLMAARNGSGF
GTKFTVSIEAAEGVTTGISAADRARTVQAAAAKDAKAEDIVSPGHIFPLMAQAGGTLARAGHTEAACDLARMAGFEPTGL
ICEVMNDDGTMSRRAELEAFALQHDIKIGTIADLIHYRMIHERTVQRIAEQPMDSELGSFNLVTYRDSVEGDVHLALTLG
TICAEEPTLVRVHNMDPLRDLLMVNQPGRWSLRAAMRAVNEAGSGVVLLLGHPLDGDVLLAHIRETAGQQPIKTPTTYST
VGAGSQILRDLGVRKMRLMSSPMKFNAISGFDLEVVEYVPSE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=199, Percent_Identity=52.2613065326633, Blast_Score=217, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=43.3497536945813, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 39544; Mature: 39413

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNSIEELVEDIRQGKMVILMDDEDRENEGDLIMAAECVKPEHINFMARFARGLICMPM
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCEEECCC
TRERCETLKLPLMAARNGSGFGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKDAKAED
CHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVSPGHIFPLMAQAGGTLARAGHTEAACDLARMAGFEPTGLICEVMNDDGTMSRRAELEA
CCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
FALQHDIKIGTIADLIHYRMIHERTVQRIAEQPMDSELGSFNLVTYRDSVEGDVHLALTL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEE
GTICAEEPTLVRVHNMDPLRDLLMVNQPGRWSLRAAMRAVNEAGSGVVLLLGHPLDGDVL
EHHHCCCCCEEEEECCCHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LAHIRETAGQQPIKTPTTYSTVGAGSQILRDLGVRKMRLMSSPMKFNAISGFDLEVVEYV
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHCC
PSE
CCC
>Mature Secondary Structure 
ALNSIEELVEDIRQGKMVILMDDEDRENEGDLIMAAECVKPEHINFMARFARGLICMPM
CCCHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCEEECCC
TRERCETLKLPLMAARNGSGFGTKFTVSIEAAEGVTTGISAADRARTVQAAAAKDAKAED
CHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IVSPGHIFPLMAQAGGTLARAGHTEAACDLARMAGFEPTGLICEVMNDDGTMSRRAELEA
CCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
FALQHDIKIGTIADLIHYRMIHERTVQRIAEQPMDSELGSFNLVTYRDSVEGDVHLALTL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEEE
GTICAEEPTLVRVHNMDPLRDLLMVNQPGRWSLRAAMRAVNEAGSGVVLLLGHPLDGDVL
EHHHCCCCCEEEEECCCHHHHHHEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LAHIRETAGQQPIKTPTTYSTVGAGSQILRDLGVRKMRLMSSPMKFNAISGFDLEVVEYV
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCHHHHCC
PSE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]