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The map label for this gene is yegD [H]

Identifier: 66047668

GI number: 66047668

Start: 5307920

End: 5309185

Strand: Direct

Name: yegD [H]

Synonym: Psyr_4441

Alternate gene names: 66047668

Gene position: 5307920-5309185 (Clockwise)

Preceding gene: 66047666

Following gene: 66047671

Centisome position: 87.11

GC content: 61.3

Gene sequence:

>1266_bases
ATGAATGACCAATCCCCGGCCCGTGCCTGCGGTATCGATTTCGGCACGTCCAACTCCACTGTCGGCTGGCAACGACCCGG
CATGGAATCGTTGATCGCGCTGGAGGACGACAAGATTACCCTGCCTTCGGTGGTGTTCTTCAATATGGAAGAGCGCCGCC
CGGTGTATGGCCGCCTGGCGCTGCACGAGTATCTGGAAGGCTATGAAGGCCGCCTGATGCGCTCGCTCAAAAGCCTGCTG
GGCTCCAAGCTGATCAAACATGACACCAGCGTGCTGGGCACAGCGATGCCCTTCAAGGATTTGCTGGCCCTGTTTATCGG
CGAGCTGAAAAAGCGCGCGGAGCAAACGGCCGGCCGCGAATTCGAGCAGGTCGTGCTGGGCCGTCCGGTGCATTTTGTCG
ATGACGACGCACAGGCCGATCAGGAAGCCGAAGACACGCTGGCTGAAGTGGCGCGCAAGATCGGCTTCAAGGACGTGTCC
TTCCAGTTCGAGCCCATCGCGGCGGCCTTCGACTACGAGTCCACCATCCAGGACGAAGAACTGGTGCTGATCGTCGACAT
TGGCGGCGGTACCTCGGACTTTTCGCTGGTGCGTCTGTCGCCCGAGCGACGCCAGCACGATGATCGCCAGCAGGACATCC
TCGCCACCGGTGGCGTGCACATCGGCGGGACCGACTTCGACAAGCAGTTGAGCCTGCAAGGCGTGATGCCGCTGTTCGGT
TATGGCAGCCGCATGAAAAGCGGTGCGTACATGCCGACCAGCCACCATATGAACCTGGCGACCTGGCACACGATCAACGC
GGTGTACTCGCAAAAGTCGCAACTGGCCCTGGGCAGCATGCGCTACGACATCGAAGACACCGGCGGCATCGATCGCCTGT
TCAAACTGATCGAACAGCGCGCCGGGCACTGGCTGGCCATGGAAGTGGAAGAAACCAAGATCCAGCTGACCCACGCCGAC
AGCCGTCACCTGCTCATGGATCGAGTGGAAGCCGGACTGAGCGTGGACCTTAGCCGGGTGATGTTCGAAGCCGCCATCGA
CGCCCAGCTTGAGCGCGTGCGCAACAGCGTGACGAACTTGCTCAACGATGCGGGAGTGAGTGTCGAACAGGTCAGCACGG
TGTTCTTCACCGGCGGTTCAAGCGGTATCCCGGCCCTGCGCAACAGCGTCTCGGACATGCTGCCCAACGCACGCCACGTC
GAAGGCAACATCTTCGGCAGCATCGGCAGCGGCCTGGCCATCGAAGCGAAGAAACGTTACGGCTAG

Upstream 100 bases:

>100_bases
GCAAATACAGCCAGGTAAATATAAGCGACGTGTCGCGCTACGCAATTTGCCCGCGCTGACATAAACTGCGCGGCCGTTTT
TTGACTGGAACGTAAAAGAC

Downstream 100 bases:

>100_bases
TCATGCGCCTATCGTGGGAATGCCCTTCGTGATGCTCCGCGTCAAAGATCGCTGATCTTGTGGGAGCGAGCTTGCTCGCG
AAGACGGATTACCTGATCAA

Product: heat shock protein YegD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MNDQSPARACGIDFGTSNSTVGWQRPGMESLIALEDDKITLPSVVFFNMEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAEQTAGREFEQVVLGRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVS
FQFEPIAAAFDYESTIQDEELVLIVDIGGGTSDFSLVRLSPERRQHDDRQQDILATGGVHIGGTDFDKQLSLQGVMPLFG
YGSRMKSGAYMPTSHHMNLATWHTINAVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIQLTHAD
SRHLLMDRVEAGLSVDLSRVMFEAAIDAQLERVRNSVTNLLNDAGVSVEQVSTVFFTGGSSGIPALRNSVSDMLPNARHV
EGNIFGSIGSGLAIEAKKRYG

Sequences:

>Translated_421_residues
MNDQSPARACGIDFGTSNSTVGWQRPGMESLIALEDDKITLPSVVFFNMEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAEQTAGREFEQVVLGRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVS
FQFEPIAAAFDYESTIQDEELVLIVDIGGGTSDFSLVRLSPERRQHDDRQQDILATGGVHIGGTDFDKQLSLQGVMPLFG
YGSRMKSGAYMPTSHHMNLATWHTINAVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIQLTHAD
SRHLLMDRVEAGLSVDLSRVMFEAAIDAQLERVRNSVTNLLNDAGVSVEQVSTVFFTGGSSGIPALRNSVSDMLPNARHV
EGNIFGSIGSGLAIEAKKRYG
>Mature_421_residues
MNDQSPARACGIDFGTSNSTVGWQRPGMESLIALEDDKITLPSVVFFNMEERRPVYGRLALHEYLEGYEGRLMRSLKSLL
GSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAEQTAGREFEQVVLGRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVS
FQFEPIAAAFDYESTIQDEELVLIVDIGGGTSDFSLVRLSPERRQHDDRQQDILATGGVHIGGTDFDKQLSLQGVMPLFG
YGSRMKSGAYMPTSHHMNLATWHTINAVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQRAGHWLAMEVEETKIQLTHAD
SRHLLMDRVEAGLSVDLSRVMFEAAIDAQLERVRNSVTNLLNDAGVSVEQVSTVFFTGGSSGIPALRNSVSDMLPNARHV
EGNIFGSIGSGLAIEAKKRYG

Specific function: Unknown

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI87082035, Length=448, Percent_Identity=29.2410714285714, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1786196, Length=442, Percent_Identity=21.4932126696833, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788875, Length=252, Percent_Identity=27.3809523809524, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17534015, Length=441, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534013, Length=441, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17507981, Length=262, Percent_Identity=29.0076335877863, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17534771, Length=438, Percent_Identity=24.8858447488584, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17568549, Length=411, Percent_Identity=24.0875912408759, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322505, Length=413, Percent_Identity=23.728813559322, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320805, Length=433, Percent_Identity=22.8637413394919, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319396, Length=443, Percent_Identity=24.3792325056433, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322426, Length=436, Percent_Identity=24.3119266055046, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320950, Length=441, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17737941, Length=253, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641406, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641408, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641402, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641404, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 46516; Mature: 46516

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDQSPARACGIDFGTSNSTVGWQRPGMESLIALEDDKITLPSVVFFNMEERRPVYGRLA
CCCCCCCHHHCCCCCCCCCCCCCCCCCHHHEEEECCCCEECCEEEEEECCCCCCHHHHHH
LHEYLEGYEGRLMRSLKSLLGSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAEQTAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHH
FEQVVLGRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVSFQFEPIAAAFDYESTIQDEE
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCHHCCCCCC
LVLIVDIGGGTSDFSLVRLSPERRQHDDRQQDILATGGVHIGGTDFDKQLSLQGVMPLFG
EEEEEECCCCCCCCEEEEECCHHHCCCHHHHHHHHCCCEEECCCCCCHHHHHCCCCHHHC
YGSRMKSGAYMPTSHHMNLATWHTINAVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQR
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHEEECCCCCCCHHHHHHHHHHH
AGHWLAMEVEETKIQLTHADSRHLLMDRVEAGLSVDLSRVMFEAAIDAQLERVRNSVTNL
CCCEEEEEEECEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDAGVSVEQVSTVFFTGGSSGIPALRNSVSDMLPNARHVEGNIFGSIGSGLAIEAKKRY
HHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCEEEECCCCCEEEEECCCC
G
C
>Mature Secondary Structure
MNDQSPARACGIDFGTSNSTVGWQRPGMESLIALEDDKITLPSVVFFNMEERRPVYGRLA
CCCCCCCHHHCCCCCCCCCCCCCCCCCHHHEEEECCCCEECCEEEEEECCCCCCHHHHHH
LHEYLEGYEGRLMRSLKSLLGSKLIKHDTSVLGTAMPFKDLLALFIGELKKRAEQTAGRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHH
FEQVVLGRPVHFVDDDAQADQEAEDTLAEVARKIGFKDVSFQFEPIAAAFDYESTIQDEE
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCHHCCCCCC
LVLIVDIGGGTSDFSLVRLSPERRQHDDRQQDILATGGVHIGGTDFDKQLSLQGVMPLFG
EEEEEECCCCCCCCEEEEECCHHHCCCHHHHHHHHCCCEEECCCCCCHHHHHCCCCHHHC
YGSRMKSGAYMPTSHHMNLATWHTINAVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQR
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHEEECCCCCCCHHHHHHHHHHH
AGHWLAMEVEETKIQLTHADSRHLLMDRVEAGLSVDLSRVMFEAAIDAQLERVRNSVTNL
CCCEEEEEEECEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDAGVSVEQVSTVFFTGGSSGIPALRNSVSDMLPNARHVEGNIFGSIGSGLAIEAKKRY
HHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCEEEECCCCCEEEEECCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7940673; 7984428 [H]