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The map label for this gene is ureC

Identifier: 66047663

GI number: 66047663

Start: 5302524

End: 5304224

Strand: Direct

Name: ureC

Synonym: Psyr_4436

Alternate gene names: 66047663

Gene position: 5302524-5304224 (Clockwise)

Preceding gene: 66047662

Following gene: 66047666

Centisome position: 87.02

GC content: 62.73

Gene sequence:

>1701_bases
ATGAAGATAAGCCGCCAAGCCTACGCAGACATGTTCGGCCCCACCGTCGGCGACAAGGTTCGCCTGGCCGACACCGAGCT
GTGGATCGAGGTCGAGAAGGACTTCACCACCTATGGCGAAGAAGTGAAGTTCGGCGGTGGCAAGGTCATTCGTGACGGCA
TGGGCCAGGGCCAGCTGCTGGCCGCCGAGGTGGTCGACACGCTGATCACCAATGCCTTGATCATCGATCACTGGGGCATC
GTCAAGGCCGACGTCGGCATCAAGAACGGGCGTATCGCGGCCATTGGCAAGGCGGGCAACCCGGACATCCAGCCGGACGT
GACCATTGCCGTCGGCGCTGCCACCGAGGTCATTGCCGGCGAAGGCATGATCCTCACCGCGGGTGGCGTCGACACGCACA
TCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCCCTGATGAGCGGCGTGACAACGATGATCGGCGGCGGCACCGGCCCG
GCCACGGGCACCAATGCCACCACCGTAACACCCGGCCCGTGGCACATGGCGCGCATGCTCCAGGCCTCGGACTCGTTCCC
GATGAACATCGGCTTCACCGGCAAGGGCAACGTCAGCCTGCCCGGCCCGCTGATCGAACAGGTCAAGGCCGGCGCCATCG
GTCTGAAGTTGCACGAGGACTGGGGCACCACGCCTGCGGCCATCGACAACTGCCTGAGCGTGGCCGACGAATACGACGTG
CAGGTCGCGATCCACACCGACACCCTCAACGAGTCGGGTTTTGTCGAGACCACCCTGGCCGCGTTCAAGAACCGCACGAT
TCACACTTATCACACCGAAGGTGCCGGTGGCGGTCATGCGCCGGACATCATCAAGGCCTGTGGCTCGCCGAACGTGCTGC
CGAGCTCGACCAACCCGACGCGTCCGTTCACCCGCAACACCATCGACGAGCACCTGGACATGCTCATGGTCTGCCATCAC
CTGGACCCGAGCATCGCCGAAGACGTGGCTTTCGCGGAAAGCCGCATCCGTCGCGAGACCATCGCTGCCGAGGATATCCT
TCACGACCTGGGCGCCTTTTCCATGCTCAGTTCCGACAGCCAGGCCATGGGCCGGGTTGGCGAAGTGATCATGCGCACCT
GGCAAACCGCCGACAAGATGAAGAAACAGCGCGGCCCACTGCCGCAGGACGGCCCGGGCAACGACAACTTCCGCGCCAAG
CGTTACATCGCCAAATACACCATCAATCCGGCGATCACCCACGGCATCAGCCATGAAGTGGGCTCCATCGAAGTCGGTAA
ATGGGCAGACCTGGTGCTGTGGCGGCCGGCGTTCTTTGGCGTCAAACCGACCCTGATCCTCAAGGGCGGGGCCATCGCTG
CCAGCCTGATGGGCGACGCCAATGCTTCAATCCCGACCCCGCAACCGGTTCATTACCGCCCGATGTTCGCAAGCTTCGGC
AGTTCACTGCACGCCACCAGCCTGACGTTCATCAGCCAGGCAGCGTTCGACGCCGGCGTACCGGAGTCACTGGGCCTGAA
AAAGCAGATCGGTGTCGTCAAAGGCTGCCGTACCGTGCAGAAAAAAGACCTGATCCACAACGATTACCTGCCGGACATCG
AAGTCGACCCGCAGACCTATCAGGTCAAGGCCGACGGCGTGCTGCTATGGTGCGAACCTGCCGATGTGCTGCCGATGGCG
CAGCGGTATTTTCTGTTTTGA

Upstream 100 bases:

>100_bases
AGCATATGACGACTAAAGACTTGCAGCTTGCAGCTTGTCGCTTTGAACACATTACAGTGTGCGGCCTGCAGCTTGCCGCT
CTGAATCCGAGGTACGAGAG

Downstream 100 bases:

>100_bases
ATCAGCAAGGGCCTTCGCTTTCAGAAGGCCCTTCAATATTTATTGCTCGGTTTATTCTTTGAGGCTAAGCAACTCGTTGA
GTTTGGCTCTGAACCAGGAC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha 2

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLLAAEVVDTLITNALIIDHWGI
VKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAGEGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTVTPGPWHMARMLQASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV
QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDSQAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAK
RYIAKYTINPAITHGISHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG
SSLHATSLTFISQAAFDAGVPESLGLKKQIGVVKGCRTVQKKDLIHNDYLPDIEVDPQTYQVKADGVLLWCEPADVLPMA
QRYFLF

Sequences:

>Translated_566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLLAAEVVDTLITNALIIDHWGI
VKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAGEGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTVTPGPWHMARMLQASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV
QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDSQAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAK
RYIAKYTINPAITHGISHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG
SSLHATSLTFISQAAFDAGVPESLGLKKQIGVVKGCRTVQKKDLIHNDYLPDIEVDPQTYQVKADGVLLWCEPADVLPMA
QRYFLF
>Mature_566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLLAAEVVDTLITNALIIDHWGI
VKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAGEGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTVTPGPWHMARMLQASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV
QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDSQAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAK
RYIAKYTINPAITHGISHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG
SSLHATSLTFISQAAFDAGVPESLGLKKQIGVVKGCRTVQKKDLIHNDYLPDIEVDPQTYQVKADGVLLWCEPADVLPMA
QRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE12_PSEU2 (Q4ZN06)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_237504.1
- ProteinModelPortal:   Q4ZN06
- SMR:   Q4ZN06
- STRING:   Q4ZN06
- GeneID:   3369976
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_4436
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   PSYR205918:PSYR_4436-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60702; Mature: 60702

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 319-319 BINDING 218-218

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLL
CCCCHHHHHHHHCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCCCCCCCH
AAEVVDTLITNALIIDHWGIVKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAG
HHHHHHHHHHCEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEC
EGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMARML
CCEEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCEECCCHHHHHHHH
QASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV
HCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE
QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPT
EEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCC
RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDS
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAKRYIAKYTINPAITHGISHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCHHHHCCCCCCC
GSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG
CCEECCCCEEEEEECHHHHCCCCEEEEECCCEEEEHHCCCCCCCCCCCCCCCCCHHHHHC
SSLHATSLTFISQAAFDAGVPESLGLKKQIGVVKGCRTVQKKDLIHNDYLPDIEVDPQTY
CCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEE
QVKADGVLLWCEPADVLPMAQRYFLF
EEEECCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MKISRQAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQGQLL
CCCCHHHHHHHHCCCCCCEEEEECCEEEEEECCCCCCCCCEEEECCCEEEECCCCCCCCH
AAEVVDTLITNALIIDHWGIVKADVGIKNGRIAAIGKAGNPDIQPDVTIAVGAATEVIAG
HHHHHHHHHHCEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEC
EGMILTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMARML
CCEEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCEECCCHHHHHHHH
QASDSFPMNIGFTGKGNVSLPGPLIEQVKAGAIGLKLHEDWGTTPAAIDNCLSVADEYDV
HCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE
QVAIHTDTLNESGFVETTLAAFKNRTIHTYHTEGAGGGHAPDIIKACGSPNVLPSSTNPT
EEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCCCC
RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMLSSDS
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVIMRTWQTADKMKKQRGPLPQDGPGNDNFRAKRYIAKYTINPAITHGISHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEEECCHHHHCCCCCCC
GSIEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFG
CCEECCCCEEEEEECHHHHCCCCEEEEECCCEEEEHHCCCCCCCCCCCCCCCCCHHHHHC
SSLHATSLTFISQAAFDAGVPESLGLKKQIGVVKGCRTVQKKDLIHNDYLPDIEVDPQTY
CCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEE
QVKADGVLLWCEPADVLPMAQRYFLF
EEEECCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA