Click here to switch to the map view.

The map label for this gene is cobL [H]

Identifier: 66047645

GI number: 66047645

Start: 5282096

End: 5283298

Strand: Direct

Name: cobL [H]

Synonym: Psyr_4418

Alternate gene names: 66047645

Gene position: 5282096-5283298 (Clockwise)

Preceding gene: 66047636

Following gene: 66047646

Centisome position: 86.68

GC content: 67.08

Gene sequence:

>1203_bases
ATGTCGCCGTGGCTGACAGTCGTGGGAATCGGGGAAGACGGTTACAAGGGGCTCGGCAAGAACGCCAGACACGCGCTGCT
GCACGCTGATCAGGTGTTCGGCGGCCCGCGCCAACTGGCGTTGCTGCCGCCGTGCATTCGCGCCGAGCGACGTGCGTGGC
CCAGCCCTTTCTCGTTGAGCCCTGTGCTCGAGCAGCGGGGTGCCGAGATCTGCGTGCTGGCCAGTGGCGACCCGATGATG
TTCGGCGTCGGCGCCAGTCTTGCACGCGTGGTCAGCATAGACGAAATGCGCATTCTGCCCGCGCCCTCCTCTTACTCTCT
GGCCGCCGCCCGCCTCGGCTGGCCCCTGCAGGACGTCGTCACCCTGTCGGTGGTTGCCCGGCCGGTGGCCGCGCTGAACG
CGCATTTCCACCATGGCATGCGCCTGCTGGTGTTGAGCAACGACGGCAGCAGCCCCGCCGTGATTGCCGGCTTGTTGCGC
GAGCGCGGCTTTGGTCCAAGCCGCATGACCGTTCTGGAGCATCTGGGTGGCGAAGCCGAACGGCGCGTCGAAGGGCTGGC
CAGCGAGTGGGGCAACCCCGAGATCGCCGCGCTGAACCTGGTTGCCATCGATTGTCGCGCCGACGCCAGCGCCATCCGTC
TGAGCCCCGTTTCAGGTCTGCCGGACAGCGCCTTCGAACATGACGGACAGCTCACCAAGCGCGACGTACGCGCCATCACC
CTCGCCCGCCTTGCACCGCTGCCGGGCGAACTGTTGTGGGATGTCGGCGCGGGCTGCGGCTCCATCGGCATCGAATGGAT
GCGCGCGCACCCGACCTGCCGGGCGATGGCCATCGAAGCCGATGAAGGCCGCCAGCAACTGATCGAATTCAACCGCGACG
CACTCGGCGTGCCCGGCCTGCAACTGGTGCGGGGCAGTGCGCCTCAGGCATTGAGCGGTCTGGAGCGCCCGGATGCGATT
TTCATCGGCGGTGGCGTGACGCGTATCGGCGTGCTGGAAACCTGCTGGGAACAACTGCGTCCGGGTGGCCGACTGGTCGC
CAATGCGGTCACCCTGCAAAGCGAAACGGCCTTGATGGCCTGGCGCGAACGGCATGGCGGCGAGCTGACCCGTATCCACG
TCGCCCACGCGCAGCCCCTTGGCGAATTCGACACGTGGCGTCAGGCGTTGCCGATCACTCTGCTGGACGTAGTCAAACCC
TGA

Upstream 100 bases:

>100_bases
TTGATTAGAGCACTTGTACCCCGTCGGGCGCGGTATTATGCCTGCTTTGTCCGCAGGCATGAAAAGGCGCTCTGTCGGAA
GTTCGGATTGAGGTAGGTAC

Downstream 100 bases:

>100_bases
TGCGCGAGGAAACCGCCGAACAACCTGCGCCACTGCGCAGTGGCCTGACCACTGGCAGCTGTGCGACCGCGACCAGCCTC
GCGGCGGCGCGGTTGTTGCT

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating)

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSPWLTVVGIGEDGYKGLGKNARHALLHADQVFGGPRQLALLPPCIRAERRAWPSPFSLSPVLEQRGAEICVLASGDPMM
FGVGASLARVVSIDEMRILPAPSSYSLAAARLGWPLQDVVTLSVVARPVAALNAHFHHGMRLLVLSNDGSSPAVIAGLLR
ERGFGPSRMTVLEHLGGEAERRVEGLASEWGNPEIAALNLVAIDCRADASAIRLSPVSGLPDSAFEHDGQLTKRDVRAIT
LARLAPLPGELLWDVGAGCGSIGIEWMRAHPTCRAMAIEADEGRQQLIEFNRDALGVPGLQLVRGSAPQALSGLERPDAI
FIGGGVTRIGVLETCWEQLRPGGRLVANAVTLQSETALMAWRERHGGELTRIHVAHAQPLGEFDTWRQALPITLLDVVKP

Sequences:

>Translated_400_residues
MSPWLTVVGIGEDGYKGLGKNARHALLHADQVFGGPRQLALLPPCIRAERRAWPSPFSLSPVLEQRGAEICVLASGDPMM
FGVGASLARVVSIDEMRILPAPSSYSLAAARLGWPLQDVVTLSVVARPVAALNAHFHHGMRLLVLSNDGSSPAVIAGLLR
ERGFGPSRMTVLEHLGGEAERRVEGLASEWGNPEIAALNLVAIDCRADASAIRLSPVSGLPDSAFEHDGQLTKRDVRAIT
LARLAPLPGELLWDVGAGCGSIGIEWMRAHPTCRAMAIEADEGRQQLIEFNRDALGVPGLQLVRGSAPQALSGLERPDAI
FIGGGVTRIGVLETCWEQLRPGGRLVANAVTLQSETALMAWRERHGGELTRIHVAHAQPLGEFDTWRQALPITLLDVVKP
>Mature_399_residues
SPWLTVVGIGEDGYKGLGKNARHALLHADQVFGGPRQLALLPPCIRAERRAWPSPFSLSPVLEQRGAEICVLASGDPMMF
GVGASLARVVSIDEMRILPAPSSYSLAAARLGWPLQDVVTLSVVARPVAALNAHFHHGMRLLVLSNDGSSPAVIAGLLRE
RGFGPSRMTVLEHLGGEAERRVEGLASEWGNPEIAALNLVAIDCRADASAIRLSPVSGLPDSAFEHDGQLTKRDVRAITL
ARLAPLPGELLWDVGAGCGSIGIEWMRAHPTCRAMAIEADEGRQQLIEFNRDALGVPGLQLVRGSAPQALSGLERPDAIF
IGGGVTRIGVLETCWEQLRPGGRLVANAVTLQSETALMAWRERHGGELTRIHVAHAQPLGEFDTWRQALPITLLDVVKP

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42855; Mature: 42724

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPWLTVVGIGEDGYKGLGKNARHALLHADQVFGGPRQLALLPPCIRAERRAWPSPFSLS
CCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
PVLEQRGAEICVLASGDPMMFGVGASLARVVSIDEMRILPAPSSYSLAAARLGWPLQDVV
HHHHHCCCCEEEEECCCCEEEECCHHHHHHHHHCCEEEECCCCCCCHHHHHHCCCHHHHH
TLSVVARPVAALNAHFHHGMRLLVLSNDGSSPAVIAGLLRERGFGPSRMTVLEHLGGEAE
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHH
RRVEGLASEWGNPEIAALNLVAIDCRADASAIRLSPVSGLPDSAFEHDGQLTKRDVRAIT
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHHH
LARLAPLPGELLWDVGAGCGSIGIEWMRAHPTCRAMAIEADEGRQQLIEFNRDALGVPGL
HHHHCCCCHHHHHHHCCCCCHHCHHEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCCCH
QLVRGSAPQALSGLERPDAIFIGGGVTRIGVLETCWEQLRPGGRLVANAVTLQSETALMA
HHHCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHH
WRERHGGELTRIHVAHAQPLGEFDTWRQALPITLLDVVKP
HHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SPWLTVVGIGEDGYKGLGKNARHALLHADQVFGGPRQLALLPPCIRAERRAWPSPFSLS
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCCCCCCC
PVLEQRGAEICVLASGDPMMFGVGASLARVVSIDEMRILPAPSSYSLAAARLGWPLQDVV
HHHHHCCCCEEEEECCCCEEEECCHHHHHHHHHCCEEEECCCCCCCHHHHHHCCCHHHHH
TLSVVARPVAALNAHFHHGMRLLVLSNDGSSPAVIAGLLRERGFGPSRMTVLEHLGGEAE
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHH
RRVEGLASEWGNPEIAALNLVAIDCRADASAIRLSPVSGLPDSAFEHDGQLTKRDVRAIT
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHHH
LARLAPLPGELLWDVGAGCGSIGIEWMRAHPTCRAMAIEADEGRQQLIEFNRDALGVPGL
HHHHCCCCHHHHHHHCCCCCHHCHHEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCCCH
QLVRGSAPQALSGLERPDAIFIGGGVTRIGVLETCWEQLRPGGRLVANAVTLQSETALMA
HHHCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHH
WRERHGGELTRIHVAHAQPLGEFDTWRQALPITLLDVVKP
HHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]