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The map label for this gene is fis [C]

Identifier: 66047632

GI number: 66047632

Start: 5267317

End: 5267637

Strand: Direct

Name: fis [C]

Synonym: Psyr_4405

Alternate gene names: 66047632

Gene position: 5267317-5267637 (Clockwise)

Preceding gene: 66047631

Following gene: 66047633

Centisome position: 86.44

GC content: 55.14

Gene sequence:

>321_bases
ATGACGATGATGACCGAGACTTTAGTGAGTGGAACAACACCCGTGAGCGACAACGTCAATTTGAAACAGCACCTCAACAC
GCCGAGCGAAGAGGGTCAGACCCTGCGCGGAAGTGTCGAGAAGGCGCTGCACAATTATTTCGCCCACCTCGAAGGCGCAT
CCGTCACTGACGTCTACAACCTGGTGTTGTCGGAAGTCGAGGCTCCGCTTCTGGAAAGCGTGATGAACTACGTCAAGGGC
AACCAGACGAAGGCCTCCGAGCTGCTGGGGCTCAATCGCGGCACGCTGCGCAAGAAACTCAAACAGTACGATCTGCTTTA
A

Upstream 100 bases:

>100_bases
ATCGTTTGGAAGATACGGAAGCACAGTGCGCCAACGTCCGGGAGTTCTTCAGCCAAGGCTGCAAGGGCCCGGATAACGAG
AATGATAAAGAGGTGGCCGC

Downstream 100 bases:

>100_bases
AGCATTCAAAACAGAAAAGGCGACCTTGCACCGCGGTCGCTTTTTTTTGCTGACTTCTTTTGCTTTTGATGGAAATCGAG
ATGACCGACCAGACTACCCG

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTMMTETLVSGTTPVSDNVNLKQHLNTPSEEGQTLRGSVEKALHNYFAHLEGASVTDVYNLVLSEVEAPLLESVMNYVKG
NQTKASELLGLNRGTLRKKLKQYDLL

Sequences:

>Translated_106_residues
MTMMTETLVSGTTPVSDNVNLKQHLNTPSEEGQTLRGSVEKALHNYFAHLEGASVTDVYNLVLSEVEAPLLESVMNYVKG
NQTKASELLGLNRGTLRKKLKQYDLL
>Mature_105_residues
TMMTETLVSGTTPVSDNVNLKQHLNTPSEEGQTLRGSVEKALHNYFAHLEGASVTDVYNLVLSEVEAPLLESVMNYVKGN
QTKASELLGLNRGTLRKKLKQYDLL

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=69, Percent_Identity=63.768115942029, Blast_Score=98, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11722; Mature: 11590

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMMTETLVSGTTPVSDNVNLKQHLNTPSEEGQTLRGSVEKALHNYFAHLEGASVTDVYN
CCCHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVLSEVEAPLLESVMNYVKGNQTKASELLGLNRGTLRKKLKQYDLL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMMTETLVSGTTPVSDNVNLKQHLNTPSEEGQTLRGSVEKALHNYFAHLEGASVTDVYN
CCHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVLSEVEAPLLESVMNYVKGNQTKASELLGLNRGTLRKKLKQYDLL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]