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The map label for this gene is gatA [H]

Identifier: 66047392

GI number: 66047392

Start: 4954141

End: 4955592

Strand: Direct

Name: gatA [H]

Synonym: Psyr_4165

Alternate gene names: 66047392

Gene position: 4954141-4955592 (Clockwise)

Preceding gene: 66047391

Following gene: 66047393

Centisome position: 81.3

GC content: 63.43

Gene sequence:

>1452_bases
ATGCATCAAATGACTCTGGCCGAGATCGCTCGCGGACTCGCCGATAAAAAGTTTTCTTCCGAAGAGCTGACTCGCGTTCT
GCTGTCGCGCATCGCGACGCTGGACCCGCAGCTCAACAGCTTCATCAGCCTCACCGAAGACCTGGCCATCACCCAGGCGC
AGGCGGCAGACGCGCGCCGTGCAGCCGGTGAAAACGGCCCGCTGCTCGGTGCCCCGCTGGCCCACAAGGACCTGTTCTGC
ACCCAGGGCATCCGCACCAGCTGCGGCTCGCTGATGCTCGACAATTTCAAGGCACCCTACGACGCCACGGTCGTGTCGCG
TCTGGCATCGGCCGGCACAGTGACGCTGGGCAAGACCAACATGGACGAATTCGCCATGGGTTCGGCCAACGAATCCAGCC
ATTACGGCGCGGTGAAAAACCCGTGGAACCTGGAATGCGTCCCTGGTGGCTCTTCGGGTGGTTCGGCAGCCGCGGTCGCT
GCACGCCTGTTGCCTGCCGCAACCGGCACCGACACCGGCGGCTCGATTCGCCAGCCTGCAGCACTGACCAACCTCACGGG
CCTCAAGCCGACCTACGGCCGCGTATCGCGCTGGGGCATGATTGCCTACGCGTCCAGCCTCGATCAGGCGGGGCCGATGG
CACGCACGGCCGAAGACTGTGCGCTGCTGCTGCAAGGCATGGCCGGTTTCGACCCGCAGGACTCCACCAGCATCGACGAA
CCGGTTCCGGACTACTCCGCCAGCCTCAATACCTCGCTCAAGGGCCTGCGTATCGGTGTGCCGAAAGAGTATTTCAGCGC
AGGCCTCGACCCGCGCATCGCGCAACTGGTGCATGAAAGCGTCAGGGAGCTGGAAAAACTCGGCGCGATCGTCAAGGAAG
TCAGCCTGCCGAACCTGCAACACGCGATCCCGGCCTACTACGTCATCGCCCCGGCTGAAGCCTCGTCCAACCTGTCGCGT
TTCGACGGTGTGCGTTTCGGCTACCGCTGCGAAGACCCGAAAGACCTGACCGACCTGTACAAGCGCTCGCGCGCCGAAGG
CTTCGGCCCGGAAGTCCAGCGACGCATCATGGTAGGCGCCTACGCGCTGTCAGCGGGTTACTACGACGCCTACTACCTGC
AGGCGCAGAAAATCCGTCGCCTGATCAAGAACGATTTCATGAACGCGTTCGCCGATGTCGACGTGATTCTCGGTCCGACC
ACGCCCAACCCGGCCTGGAAAATCGGCGCCAAGACCCACGACCCGATTGCCGAATACCTGGAAGACTTCTACACCATCAC
CGCCAACCTGGCGGGCCTGCCCGGCTTGTCCATGCCTGCGGGCTTCGTCGACGGCCTGCCGGTCGGCGTGCAGCTGCTCG
CTCCGTATTTCCAGGAAGGCCGCCTCTTGAATGTGGCGCATCAGTATCAGCAAGTCACCGACTGGCACACTCGCGCACCT
GAAGGCTTCTGA

Upstream 100 bases:

>100_bases
CCGAGCGAAATCGTCGTGACACTTACCAAGCCATCGCACCAGCGGTCCAAGACGGGCTGTATCTGGTTCCGAAAGTCATC
GAGTAAGGGAAAGCGCCTGC

Downstream 100 bases:

>100_bases
GGAGAAACACATGCAATGGGAAGTCGTCATCGGGCTGGAGATTCATACCCAGCTTTCGACCCAATCAAAGATTTTTTCCG
GTAGCGCGACCACGTTCGGC

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHQMTLAEIARGLADKKFSSEELTRVLLSRIATLDPQLNSFISLTEDLAITQAQAADARRAAGENGPLLGAPLAHKDLFC
TQGIRTSCGSLMLDNFKAPYDATVVSRLASAGTVTLGKTNMDEFAMGSANESSHYGAVKNPWNLECVPGGSSGGSAAAVA
ARLLPAATGTDTGGSIRQPAALTNLTGLKPTYGRVSRWGMIAYASSLDQAGPMARTAEDCALLLQGMAGFDPQDSTSIDE
PVPDYSASLNTSLKGLRIGVPKEYFSAGLDPRIAQLVHESVRELEKLGAIVKEVSLPNLQHAIPAYYVIAPAEASSNLSR
FDGVRFGYRCEDPKDLTDLYKRSRAEGFGPEVQRRIMVGAYALSAGYYDAYYLQAQKIRRLIKNDFMNAFADVDVILGPT
TPNPAWKIGAKTHDPIAEYLEDFYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVTDWHTRAP
EGF

Sequences:

>Translated_483_residues
MHQMTLAEIARGLADKKFSSEELTRVLLSRIATLDPQLNSFISLTEDLAITQAQAADARRAAGENGPLLGAPLAHKDLFC
TQGIRTSCGSLMLDNFKAPYDATVVSRLASAGTVTLGKTNMDEFAMGSANESSHYGAVKNPWNLECVPGGSSGGSAAAVA
ARLLPAATGTDTGGSIRQPAALTNLTGLKPTYGRVSRWGMIAYASSLDQAGPMARTAEDCALLLQGMAGFDPQDSTSIDE
PVPDYSASLNTSLKGLRIGVPKEYFSAGLDPRIAQLVHESVRELEKLGAIVKEVSLPNLQHAIPAYYVIAPAEASSNLSR
FDGVRFGYRCEDPKDLTDLYKRSRAEGFGPEVQRRIMVGAYALSAGYYDAYYLQAQKIRRLIKNDFMNAFADVDVILGPT
TPNPAWKIGAKTHDPIAEYLEDFYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVTDWHTRAP
EGF
>Mature_483_residues
MHQMTLAEIARGLADKKFSSEELTRVLLSRIATLDPQLNSFISLTEDLAITQAQAADARRAAGENGPLLGAPLAHKDLFC
TQGIRTSCGSLMLDNFKAPYDATVVSRLASAGTVTLGKTNMDEFAMGSANESSHYGAVKNPWNLECVPGGSSGGSAAAVA
ARLLPAATGTDTGGSIRQPAALTNLTGLKPTYGRVSRWGMIAYASSLDQAGPMARTAEDCALLLQGMAGFDPQDSTSIDE
PVPDYSASLNTSLKGLRIGVPKEYFSAGLDPRIAQLVHESVRELEKLGAIVKEVSLPNLQHAIPAYYVIAPAEASSNLSR
FDGVRFGYRCEDPKDLTDLYKRSRAEGFGPEVQRRIMVGAYALSAGYYDAYYLQAQKIRRLIKNDFMNAFADVDVILGPT
TPNPAWKIGAKTHDPIAEYLEDFYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVTDWHTRAP
EGF

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=494, Percent_Identity=39.6761133603239, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI195972892, Length=491, Percent_Identity=27.2912423625255, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI166795287, Length=267, Percent_Identity=29.9625468164794, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=436, Percent_Identity=38.9908256880734, Blast_Score=284, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI17537465, Length=483, Percent_Identity=26.7080745341615, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17556264, Length=317, Percent_Identity=26.1829652996845, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538252, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71990152, Length=240, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556276, Length=315, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=315, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323950, Length=463, Percent_Identity=33.2613390928726, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6319685, Length=483, Percent_Identity=31.6770186335404, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6320448, Length=194, Percent_Identity=32.9896907216495, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648113, Length=485, Percent_Identity=40.6185567010309, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24652985, Length=485, Percent_Identity=24.7422680412371, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI19922090, Length=485, Percent_Identity=24.7422680412371, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24652981, Length=485, Percent_Identity=24.7422680412371, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24652983, Length=485, Percent_Identity=24.7422680412371, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI161078093, Length=504, Percent_Identity=28.3730158730159, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24644968, Length=513, Percent_Identity=25.7309941520468, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45550774, Length=499, Percent_Identity=24.0480961923848, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648435, Length=499, Percent_Identity=24.0480961923848, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648437, Length=499, Percent_Identity=24.0480961923848, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356731, Length=485, Percent_Identity=23.2989690721649, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24648441, Length=430, Percent_Identity=24.1860465116279, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648439, Length=430, Percent_Identity=24.1860465116279, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 51916; Mature: 51916

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQMTLAEIARGLADKKFSSEELTRVLLSRIATLDPQLNSFISLTEDLAITQAQAADARR
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAGENGPLLGAPLAHKDLFCTQGIRTSCGSLMLDNFKAPYDATVVSRLASAGTVTLGKTN
HCCCCCCEECCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
MDEFAMGSANESSHYGAVKNPWNLECVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPA
HHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
ALTNLTGLKPTYGRVSRWGMIAYASSLDQAGPMARTAEDCALLLQGMAGFDPQDSTSIDE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PVPDYSASLNTSLKGLRIGVPKEYFSAGLDPRIAQLVHESVRELEKLGAIVKEVSLPNLQ
CCCCCCCCCCCCCCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HAIPAYYVIAPAEASSNLSRFDGVRFGYRCEDPKDLTDLYKRSRAEGFGPEVQRRIMVGA
HHCCEEEEEECCCCCCCHHHHCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YALSAGYYDAYYLQAQKIRRLIKNDFMNAFADVDVILGPTTPNPAWKIGAKTHDPIAEYL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCHHHHHH
EDFYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVTDWHTRAP
HHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCC
EGF
CCC
>Mature Secondary Structure
MHQMTLAEIARGLADKKFSSEELTRVLLSRIATLDPQLNSFISLTEDLAITQAQAADARR
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AAGENGPLLGAPLAHKDLFCTQGIRTSCGSLMLDNFKAPYDATVVSRLASAGTVTLGKTN
HCCCCCCEECCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCC
MDEFAMGSANESSHYGAVKNPWNLECVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPA
HHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
ALTNLTGLKPTYGRVSRWGMIAYASSLDQAGPMARTAEDCALLLQGMAGFDPQDSTSIDE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PVPDYSASLNTSLKGLRIGVPKEYFSAGLDPRIAQLVHESVRELEKLGAIVKEVSLPNLQ
CCCCCCCCCCCCCCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HAIPAYYVIAPAEASSNLSRFDGVRFGYRCEDPKDLTDLYKRSRAEGFGPEVQRRIMVGA
HHCCEEEEEECCCCCCCHHHHCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YALSAGYYDAYYLQAQKIRRLIKNDFMNAFADVDVILGPTTPNPAWKIGAKTHDPIAEYL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECCCCCCHHHHHH
EDFYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVTDWHTRAP
HHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCCC
EGF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA