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The map label for this gene is mreD [H]

Identifier: 66047388

GI number: 66047388

Start: 4950807

End: 4951298

Strand: Reverse

Name: mreD [H]

Synonym: Psyr_4161

Alternate gene names: 66047388

Gene position: 4951298-4950807 (Counterclockwise)

Preceding gene: 66047389

Following gene: 66047387

Centisome position: 81.25

GC content: 59.15

Gene sequence:

>492_bases
ATGGTTAGTCATGTTTCCGGGCGCAATGGCTGGGTGGTCTGGCTGACGTTTGCGATCGGTCTGCTGCTGAGCGTTTCGCC
GCTGCCGCAATTCATGGAAATCTTCCGGCCACTGTGGCTGGCCCTGCTGCTGACCTTCTGGGTTCTGGCGCTGCCGCACA
AATACGGCATGACCACCGCGTGGATACTGGGCCTGATGGAGGATGTGCTGTACGGCACCTTGCTCGGCCAGAACGCCCTG
ATCCTCAGTCTGATCACCTTTCTGGTGATGTCCCTGCAGCAGCGCCTGCGCATGTTTCCCATGTGGCAACAATGCCTGGT
GCTGCTGGTGGTATTCGGTCTGGCACAGCTTGCGCAACTCTGGCTCAGCGCGCTGACCGGCAACCGTCAGCCAACGCTGG
CGCTGGTGCTGCCCGCGTTGGTCAGTGCTCTGTTGTGGCCCTGGATCAGTTATGGCCTGCGTGGATTGCGCAAACGTTTG
AAAATCAATTAA

Upstream 100 bases:

>100_bases
GCACCGGCGGCCACGCCCGCGACACCGGCAAGGCCTGCTGCCCGGCCTGCGGCGTCACAGCCGCCTGCTTCACGACCTTC
CACTGCCCGGGAGCCTATCG

Downstream 100 bases:

>100_bases
GCGCAAGGTGAGCGCGACGCCCCGCTGCGTTGTTCGCGCTCACCCGCACAGACACGGAGATGTCCTTATGCCCTCGCTTT
ATCTGGCTTCTGGCTCGCCG

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MVSHVSGRNGWVVWLTFAIGLLLSVSPLPQFMEIFRPLWLALLLTFWVLALPHKYGMTTAWILGLMEDVLYGTLLGQNAL
ILSLITFLVMSLQQRLRMFPMWQQCLVLLVVFGLAQLAQLWLSALTGNRQPTLALVLPALVSALLWPWISYGLRGLRKRL
KIN

Sequences:

>Translated_163_residues
MVSHVSGRNGWVVWLTFAIGLLLSVSPLPQFMEIFRPLWLALLLTFWVLALPHKYGMTTAWILGLMEDVLYGTLLGQNAL
ILSLITFLVMSLQQRLRMFPMWQQCLVLLVVFGLAQLAQLWLSALTGNRQPTLALVLPALVSALLWPWISYGLRGLRKRL
KIN
>Mature_163_residues
MVSHVSGRNGWVVWLTFAIGLLLSVSPLPQFMEIFRPLWLALLLTFWVLALPHKYGMTTAWILGLMEDVLYGTLLGQNAL
ILSLITFLVMSLQQRLRMFPMWQQCLVLLVVFGLAQLAQLWLSALTGNRQPTLALVLPALVSALLWPWISYGLRGLRKRL
KIN

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=163, Percent_Identity=33.7423312883436, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18513; Mature: 18513

Theoretical pI: Translated: 11.46; Mature: 11.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSHVSGRNGWVVWLTFAIGLLLSVSPLPQFMEIFRPLWLALLLTFWVLALPHKYGMTTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHH
WILGLMEDVLYGTLLGQNALILSLITFLVMSLQQRLRMFPMWQQCLVLLVVFGLAQLAQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSALTGNRQPTLALVLPALVSALLWPWISYGLRGLRKRLKIN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSHVSGRNGWVVWLTFAIGLLLSVSPLPQFMEIFRPLWLALLLTFWVLALPHKYGMTTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHH
WILGLMEDVLYGTLLGQNALILSLITFLVMSLQQRLRMFPMWQQCLVLLVVFGLAQLAQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSALTGNRQPTLALVLPALVSALLWPWISYGLRGLRKRLKIN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]