Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 66047383

GI number: 66047383

Start: 4942351

End: 4943790

Strand: Reverse

Name: tldD [H]

Synonym: Psyr_4156

Alternate gene names: 66047383

Gene position: 4943790-4942351 (Counterclockwise)

Preceding gene: 66047384

Following gene: 66047381

Centisome position: 81.13

GC content: 63.33

Gene sequence:

>1440_bases
ATGAGTGATCTGTCCTCAGTCAGCGAACACCTTCTGGCACCCGGCGGCCTGAACCTCGACAGCCTGCAGTCCGTGCTGGG
CGATCTGGCCGGACCAGGCATCGACGCGGCCGATCTGTATTTTCAGGGCATGATCTCCGAGTCCTGGTCGCTCGAAGACG
GGATCGTCAAGGAAGGCAGTTTCAATCTCGATCAAGGCGTTGGCGTGCGTGCCCAGTCGGGCGAGAAAACCGGCTTTGCG
TACAGCAACGCGATCACCCCCGAGGCCCTGCGCACCGCCGCACAGGCCGCGCGCTCTATTTCCCGCGCAGGCCAGAATGG
TCGCGTGCAGGCTTTCACCTCGCAGGACGTGGCACAGTTGTATGCCCCGGACAACCCGCTGGAAGTACTGAGCCGCGCCG
AGAAAGTCGAGTTGCTCAAGCGCATCGACGTCGCAACGCGTGCGCTGGACTCGCGTATCCAGCAGGTTTCGGTGAGCATG
GCCGGTGTCTGGGAGCGCATCCTGGTGGCCGCCGCGGATGGCAGCCTGGCCGCTGATGTGCGACCGCTGGTGCGTTTCAA
CGTCAGTGTCATCGTCGAGCAGAATGGCCGTCGCGAGCGTGGCGGGCATGGCGGCGGCGGGCGTACCGATTACCGTTATT
TCCTGACCGACGATCGCGCCATGGGCTACGCCCGTGAGGCCCTGCGTCAGGCACTGGTCAACCTGGAAGCGATTCCTGCA
CCGGCAGGCACCTTGCCGGTGGTACTCGGCTCCGGCTGGTCCGGTGTGCTGCTGCACGAAGCGGTCGGTCACGGCCTTGA
GGGTGACTTCAACCGCAAGGGCAGCTCGGCCTACAGCGGGCGCATGGGCGAGATGGTTGCCTCGAAACTCTGCACCATCG
TCGACGACGGCACCCTGGCGGGGCGTCGTGGCTCGCTGAGCGTGGATGACGAAGGCACACCGACCGAATGCACTACGCTG
ATCGAGAACGGCGTACTCAAGGGCTACATGCAGGACAAACTCAATGCGCGCCTGATGGGTGTGGCGCGCACCGGCAACGG
CCGTCGCGAGTCCTATGCCCACCTGCCGATGCCGCGCATGACCAACACCTACATGCTGGGCGGGCAGAGCGATCCGCAGG
AAATCATCGCCTCAGTAAAGCGCGGCATCTATTGCGCCAACCTGGGCGGTGGTCAGGTGGATATCACCAGCGGCAAGTTC
GTGTTTTCGACCAGTGAGGCCTATTTGATCGAAGATGGCAAGATCACTGCGCCGGTCAAAGGCGCGACCTTGATCGGTAA
CGGGCCGGAAGCCATGAGCAGGGTATCGATGGTGGGTAACGATCTGTCGCTGGACAGTGGCGTCGGCACATGCGGGAAAG
ATGGCCAGTCGCTGCCGGTCGGTGTGGGTCAGCCTACGCTGAAAATCGACGCGATTACCGTGGGTGGCACCGGTAGCTGA

Upstream 100 bases:

>100_bases
GCGACAGTGAAGAACAGGCGTCCATACGGGCGCGGATGCCGGTGTCCAGTCACCGGCGCTTTTTTTCGCAGGACGCCATG
CGGCCTGCTTCGGAGTGAAT

Downstream 100 bases:

>100_bases
AAGTGAGTCGGGGCCGGCTGCTTGCTGCCGCCGGCCCCGAGGGCGAATTCAACGCAGACCGCGTTGAAGTTCGTCCAGCT
CACGGATGTATTTGAAGATT

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSDLSSVSEHLLAPGGLNLDSLQSVLGDLAGPGIDAADLYFQGMISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGFA
YSNAITPEALRTAAQAARSISRAGQNGRVQAFTSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDSRIQQVSVSM
AGVWERILVAAADGSLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLTDDRAMGYAREALRQALVNLEAIPA
PAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLAGRRGSLSVDDEGTPTECTTL
IENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPQEIIASVKRGIYCANLGGGQVDITSGKF
VFSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLSLDSGVGTCGKDGQSLPVGVGQPTLKIDAITVGGTGS

Sequences:

>Translated_479_residues
MSDLSSVSEHLLAPGGLNLDSLQSVLGDLAGPGIDAADLYFQGMISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGFA
YSNAITPEALRTAAQAARSISRAGQNGRVQAFTSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDSRIQQVSVSM
AGVWERILVAAADGSLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLTDDRAMGYAREALRQALVNLEAIPA
PAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLAGRRGSLSVDDEGTPTECTTL
IENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPQEIIASVKRGIYCANLGGGQVDITSGKF
VFSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLSLDSGVGTCGKDGQSLPVGVGQPTLKIDAITVGGTGS
>Mature_478_residues
SDLSSVSEHLLAPGGLNLDSLQSVLGDLAGPGIDAADLYFQGMISESWSLEDGIVKEGSFNLDQGVGVRAQSGEKTGFAY
SNAITPEALRTAAQAARSISRAGQNGRVQAFTSQDVAQLYAPDNPLEVLSRAEKVELLKRIDVATRALDSRIQQVSVSMA
GVWERILVAAADGSLAADVRPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLTDDRAMGYAREALRQALVNLEAIPAP
AGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLAGRRGSLSVDDEGTPTECTTLI
ENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRMTNTYMLGGQSDPQEIIASVKRGIYCANLGGGQVDITSGKFV
FSTSEAYLIEDGKITAPVKGATLIGNGPEAMSRVSMVGNDLSLDSGVGTCGKDGQSLPVGVGQPTLKIDAITVGGTGS

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=478, Percent_Identity=65.8995815899582, Blast_Score=623, Evalue=1e-180,
Organism=Escherichia coli, GI1790682, Length=438, Percent_Identity=24.2009132420091, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50243; Mature: 50112

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSSVSEHLLAPGGLNLDSLQSVLGDLAGPGIDAADLYFQGMISESWSLEDGIVKEGS
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
FNLDQGVGVRAQSGEKTGFAYSNAITPEALRTAAQAARSISRAGQNGRVQAFTSQDVAQL
CCCCCCCCCEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHH
YAPDNPLEVLSRAEKVELLKRIDVATRALDSRIQQVSVSMAGVWERILVAAADGSLAADV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHC
RPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLTDDRAMGYAREALRQALVNLEAIPA
HHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLA
CCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GRRGSLSVDDEGTPTECTTLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCC
TNTYMLGGQSDPQEIIASVKRGIYCANLGGGQVDITSGKFVFSTSEAYLIEDGKITAPVK
CCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCEEEEECCEEECCCC
GATLIGNGPEAMSRVSMVGNDLSLDSGVGTCGKDGQSLPVGVGQPTLKIDAITVGGTGS
CCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
SDLSSVSEHLLAPGGLNLDSLQSVLGDLAGPGIDAADLYFQGMISESWSLEDGIVKEGS
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
FNLDQGVGVRAQSGEKTGFAYSNAITPEALRTAAQAARSISRAGQNGRVQAFTSQDVAQL
CCCCCCCCCEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHH
YAPDNPLEVLSRAEKVELLKRIDVATRALDSRIQQVSVSMAGVWERILVAAADGSLAADV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHC
RPLVRFNVSVIVEQNGRRERGGHGGGGRTDYRYFLTDDRAMGYAREALRQALVNLEAIPA
HHHHEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PAGTLPVVLGSGWSGVLLHEAVGHGLEGDFNRKGSSAYSGRMGEMVASKLCTIVDDGTLA
CCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GRRGSLSVDDEGTPTECTTLIENGVLKGYMQDKLNARLMGVARTGNGRRESYAHLPMPRM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCC
TNTYMLGGQSDPQEIIASVKRGIYCANLGGGQVDITSGKFVFSTSEAYLIEDGKITAPVK
CCEEEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEECCCEEEEECCEEECCCC
GATLIGNGPEAMSRVSMVGNDLSLDSGVGTCGKDGQSLPVGVGQPTLKIDAITVGGTGS
CCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]