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The map label for this gene is lptA [H]

Identifier: 66047372

GI number: 66047372

Start: 4933120

End: 4933668

Strand: Direct

Name: lptA [H]

Synonym: Psyr_4145

Alternate gene names: 66047372

Gene position: 4933120-4933668 (Clockwise)

Preceding gene: 66047371

Following gene: 66047373

Centisome position: 80.95

GC content: 56.83

Gene sequence:

>549_bases
ATGAGGCTCGTTAAAACTCTTCCTTTATTGCTCGGCCTGGGCGCAGCACTGGGAAGCGCGAGCGCCTGGTCCCTGCCAAC
CGACCGAGATCAGCCTATCCACATCCAGTCTGACGATGCTCAGCTCGATGACAAGAAAGGCGTGGCGACCTACAAGGGCA
ATGTCATCATCACTCAGGGCTCGATGAAAATCACGGGCAACACCGTGACAATCACGCGTAATGCCCAGGGCGAAGTCGAC
GTCTTCACCTCCGTCGGCAACCTGGCTTACTACGAGCAGAAGCCTGCCGTAGACAAACCGATCGTGCAGGCCTATGCCGT
CACCATCCAGTATTACGCTGGCCAGGACCGTATCGTCCTGATCGACAAGGCCAAGGTCATCAATGATGGCAACACCTCGG
AAGGCGAGAAAATCGTCTACGACACGGTTAGACAGGTCGTCACCGCCGGTCGGGCCAATGGCGGCGCCAAGGTGACCACA
CCACGTCCGCGTATCGACATGGTCATCCAGCCGAAAAAGAAAACCGATCAACCTCAGAAGGCCCAGTAA

Upstream 100 bases:

>100_bases
GTTAGAATCGACGGCGCGGGCGGTGTCACTACGGCCAAGGGAATGAAAGCGTATTTGAAAGACAGCAGGATGGACCTGCT
GTCCAACGTAAGAGGACAGT

Downstream 100 bases:

>100_bases
ATGGCGACGCTCAAAGCCCAGCATCTCGCTAAAAGCTACAAAAGCCGGCAGGTCGTGCGCGATGTGAGCATTTCCATCGA
CAGCGGCCAGATCGTCGGCC

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MRLVKTLPLLLGLGAALGSASAWSLPTDRDQPIHIQSDDAQLDDKKGVATYKGNVIITQGSMKITGNTVTITRNAQGEVD
VFTSVGNLAYYEQKPAVDKPIVQAYAVTIQYYAGQDRIVLIDKAKVINDGNTSEGEKIVYDTVRQVVTAGRANGGAKVTT
PRPRIDMVIQPKKKTDQPQKAQ

Sequences:

>Translated_182_residues
MRLVKTLPLLLGLGAALGSASAWSLPTDRDQPIHIQSDDAQLDDKKGVATYKGNVIITQGSMKITGNTVTITRNAQGEVD
VFTSVGNLAYYEQKPAVDKPIVQAYAVTIQYYAGQDRIVLIDKAKVINDGNTSEGEKIVYDTVRQVVTAGRANGGAKVTT
PRPRIDMVIQPKKKTDQPQKAQ
>Mature_182_residues
MRLVKTLPLLLGLGAALGSASAWSLPTDRDQPIHIQSDDAQLDDKKGVATYKGNVIITQGSMKITGNTVTITRNAQGEVD
VFTSVGNLAYYEQKPAVDKPIVQAYAVTIQYYAGQDRIVLIDKAKVINDGNTSEGEKIVYDTVRQVVTAGRANGGAKVTT
PRPRIDMVIQPKKKTDQPQKAQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=180, Percent_Identity=35, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19696; Mature: 19696

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVKTLPLLLGLGAALGSASAWSLPTDRDQPIHIQSDDAQLDDKKGVATYKGNVIITQG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCEEEECC
SMKITGNTVTITRNAQGEVDVFTSVGNLAYYEQKPAVDKPIVQAYAVTIQYYAGQDRIVL
CEEEECCEEEEEECCCCCEEEEEECCCEEEECCCCCCCCHHHEEEEEEEEEECCCCEEEE
IDKAKVINDGNTSEGEKIVYDTVRQVVTAGRANGGAKVTTPRPRIDMVIQPKKKTDQPQK
EECEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCC
AQ
CC
>Mature Secondary Structure
MRLVKTLPLLLGLGAALGSASAWSLPTDRDQPIHIQSDDAQLDDKKGVATYKGNVIITQG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCEEEECC
SMKITGNTVTITRNAQGEVDVFTSVGNLAYYEQKPAVDKPIVQAYAVTIQYYAGQDRIVL
CEEEECCEEEEEECCCCCEEEEEECCCEEEECCCCCCCCHHHEEEEEEEEEECCCCEEEE
IDKAKVINDGNTSEGEKIVYDTVRQVVTAGRANGGAKVTTPRPRIDMVIQPKKKTDQPQK
EECEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCC
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]