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The map label for this gene is kdsC [H]

Identifier: 66047370

GI number: 66047370

Start: 4932043

End: 4932552

Strand: Direct

Name: kdsC [H]

Synonym: Psyr_4143

Alternate gene names: 66047370

Gene position: 4932043-4932552 (Clockwise)

Preceding gene: 66047369

Following gene: 66047371

Centisome position: 80.94

GC content: 57.84

Gene sequence:

>510_bases
ATGCAACGCGGCAAGGCCATCAAGCTGGCAGTCTTCGATGTCGATGGCGTGCTGACCGATGGCCGCCTTTACTTCATGGA
AGACGGCAGCGAGATCAAGACATTCAATACCCTCGACGGCCAGGGCATTAAAATGCTGATAGCCTCGGGCGTCACCACGG
CGATCATCAGTGGCCGCAAGACCGCGATAGTCGAGCGCCGGGCAAAGAGCCTGGGCATTGAACACCTGTTTCAGGGACGT
GAAGACAAACTGGTGGTACTGGACAAGTTGCTGGCAGAACTCAACCTGAGTTACGAACAGGTCGCCTATCTGGGTGATGA
TCTGCCAGACTTGCCCGTCATCAGACGCGTCGGTCTGGGCATGGCAGTGGCCAATGCTGCCGGCTTTGTACGCGAGCACG
CACACGGGATAACCAGGGCGCGAGGCGGCGAAGGTGCAGCGCGCGAATTCTGCGAACTGATTCTGAGTGCGCAAGGCAAC
CTTGAAGCGGCTCACTCCGCCTATTTATAG

Upstream 100 bases:

>100_bases
TCGTAGACCAGAACGACCGGCCGGTTGGCGCATTCAACCTGCAGGATCTCCTGCGCGCAGGCGTCATGTAATGGAAACCG
AAATAATGACTCAGGATCTC

Downstream 100 bases:

>100_bases
AAGCCATTATGTTCACTAAAAAAATTCGCAAGTTCCTGCTTCTCGGGGTACTGGCGCTGCTGCTGGCAGCGGTCGGTTAC
TGGAACATCAGCCCGGAAAG

Product: HAD family phosphatase YrbI

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQRGKAIKLAVFDVDGVLTDGRLYFMEDGSEIKTFNTLDGQGIKMLIASGVTTAIISGRKTAIVERRAKSLGIEHLFQGR
EDKLVVLDKLLAELNLSYEQVAYLGDDLPDLPVIRRVGLGMAVANAAGFVREHAHGITRARGGEGAAREFCELILSAQGN
LEAAHSAYL

Sequences:

>Translated_169_residues
MQRGKAIKLAVFDVDGVLTDGRLYFMEDGSEIKTFNTLDGQGIKMLIASGVTTAIISGRKTAIVERRAKSLGIEHLFQGR
EDKLVVLDKLLAELNLSYEQVAYLGDDLPDLPVIRRVGLGMAVANAAGFVREHAHGITRARGGEGAAREFCELILSAQGN
LEAAHSAYL
>Mature_169_residues
MQRGKAIKLAVFDVDGVLTDGRLYFMEDGSEIKTFNTLDGQGIKMLIASGVTTAIISGRKTAIVERRAKSLGIEHLFQGR
EDKLVVLDKLLAELNLSYEQVAYLGDDLPDLPVIRRVGLGMAVANAAGFVREHAHGITRARGGEGAAREFCELILSAQGN
LEAAHSAYL

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=36.8421052631579, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI2367202, Length=164, Percent_Identity=46.9512195121951, Blast_Score=156, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18255; Mature: 18255

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGKAIKLAVFDVDGVLTDGRLYFMEDGSEIKTFNTLDGQGIKMLIASGVTTAIISGRK
CCCCCEEEEEEEECCCEEECCEEEEEECCCCEEEEECCCCCCHHHHHHCCHHHHHHCCCH
TAIVERRAKSLGIEHLFQGREDKLVVLDKLLAELNLSYEQVAYLGDDLPDLPVIRRVGLG
HHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHCCC
MAVANAAGFVREHAHGITRARGGEGAAREFCELILSAQGNLEAAHSAYL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure
MQRGKAIKLAVFDVDGVLTDGRLYFMEDGSEIKTFNTLDGQGIKMLIASGVTTAIISGRK
CCCCCEEEEEEEECCCEEECCEEEEEECCCCEEEEECCCCCCHHHHHHCCHHHHHHCCCH
TAIVERRAKSLGIEHLFQGREDKLVVLDKLLAELNLSYEQVAYLGDDLPDLPVIRRVGLG
HHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHCCC
MAVANAAGFVREHAHGITRARGGEGAAREFCELILSAQGNLEAAHSAYL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]