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The map label for this gene is degP1 [H]

Identifier: 66047357

GI number: 66047357

Start: 4919176

End: 4920336

Strand: Direct

Name: degP1 [H]

Synonym: Psyr_4130

Alternate gene names: 66047357

Gene position: 4919176-4920336 (Clockwise)

Preceding gene: 66047352

Following gene: 66047369

Centisome position: 80.73

GC content: 60.9

Gene sequence:

>1161_bases
ATGTTCAAGGCACTGCGTTTTTTCGGCTGGCCATTGCTGGCTGGCGTGCTTATCGCCATGCTGATTATTCAGCGCTATCC
GCAGTGGGTCGGCCTGCCGAGCCTGGATGTCAATCTGCAACAGGCCCCGCAGACCACCAATGTCATGCAAGGTCCGTCTT
CCTATGCCGACGCGGTCATTGCCGCAGCGCCCGCGGTGGTCAACCTCTATACCACCAAGATGGTCAACAAGGGCAACAAC
CCGCTTTTCGAAGACCCGCAGTTCCGACGCTTCTTCGGCGATAACACGCCCAAGCAGAAGCGCATGGAATCGAGCCTGGG
CTCTGGCGTCATGATGAGCCCCGAAGGCTACATACTGACCAACAACCACGTCACCACCGGCGCTGACCAGATCGTGGTCG
CGCTCAAGGACGGCCGTGAAACCATTGCCCGGGTCATCGGCAATGACCCGGAAACCGACCTGGCGGTGCTCAAGATCGAC
CTGAAAAATCTGCCGGCGATTACCATCGCGCGCTCTGACAGCATCCGCATCGGCGATGTTGCGCTGGCGATCGGCAACCC
GTTCGGGGTCGGCCAGACCGTGACCATGGGCATCATCAGTGCCACCGGGCGCAATCAGTTGGGCCTCAACACCTATGAAG
ACTTCATTCAGACCGATGCGGCCATCAACCCGGGTAACTCGGGCGGCGCACTGGTGGACGCCAGCGGCAACCTGATCGGT
ATCAATACCGCGATCTTTTCCAAGTCCGGCGGCTCGCAGGGCATCGGCTTCGCCATTCCGACCAAGCTGGCCATGGATGT
CATGAAGTCGATCATCGAGCACGGTCAGGTCATTCGTGGCTGGCTGGGCATCGAAGTTCAACCCCTGACTCAGGAACTGG
CCGAATCCTTCGGACTGAAGGATCGTCCAGGCATCGTTGTGGCGGGCATCTTCCGCGACGGCCCGGCGCAGAAAGCCGGA
CTGCAACTGGGTGACGTGATCCTGAGCATCAATGGCGAACCTGCCGGCGACGGGCGTCGTTCGATGAACCAGGTGGCGCG
CACCAAACCCAAGGACAAGATTGCTATCGACGTGATGCGCAACGGCAAGGAAATGCGCCTGAGCGCCGAAGTCGGCCTGC
GTCCACCGCCCGCCCCTACCCCGGTTGCAGCGCCGGAGTGA

Upstream 100 bases:

>100_bases
AAATATGCAGTTCAGAGCTGCGTTGTACTCGTATAATGCCCGCCATTATGGCGCACCCGTGGCAAAACTTTCTGCGCCCG
CAACCATCAGGACTTGTTAA

Downstream 100 bases:

>100_bases
TGCGCCAGTACCTCAAAATGAGGTACAGCACAGATCAGTGACGCCCGAAATAAAGGGCGTCCAGGCTTGTGCCCAAAGGA
CGTGGGCGCCAGCTGCTCGC

Product: peptidase S1, chymotrypsin:PDZ/DHR/GLGF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFKALRFFGWPLLAGVLIAMLIIQRYPQWVGLPSLDVNLQQAPQTTNVMQGPSSYADAVIAAAPAVVNLYTTKMVNKGNN
PLFEDPQFRRFFGDNTPKQKRMESSLGSGVMMSPEGYILTNNHVTTGADQIVVALKDGRETIARVIGNDPETDLAVLKID
LKNLPAITIARSDSIRIGDVALAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQTDAAINPGNSGGALVDASGNLIG
INTAIFSKSGGSQGIGFAIPTKLAMDVMKSIIEHGQVIRGWLGIEVQPLTQELAESFGLKDRPGIVVAGIFRDGPAQKAG
LQLGDVILSINGEPAGDGRRSMNQVARTKPKDKIAIDVMRNGKEMRLSAEVGLRPPPAPTPVAAPE

Sequences:

>Translated_386_residues
MFKALRFFGWPLLAGVLIAMLIIQRYPQWVGLPSLDVNLQQAPQTTNVMQGPSSYADAVIAAAPAVVNLYTTKMVNKGNN
PLFEDPQFRRFFGDNTPKQKRMESSLGSGVMMSPEGYILTNNHVTTGADQIVVALKDGRETIARVIGNDPETDLAVLKID
LKNLPAITIARSDSIRIGDVALAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQTDAAINPGNSGGALVDASGNLIG
INTAIFSKSGGSQGIGFAIPTKLAMDVMKSIIEHGQVIRGWLGIEVQPLTQELAESFGLKDRPGIVVAGIFRDGPAQKAG
LQLGDVILSINGEPAGDGRRSMNQVARTKPKDKIAIDVMRNGKEMRLSAEVGLRPPPAPTPVAAPE
>Mature_386_residues
MFKALRFFGWPLLAGVLIAMLIIQRYPQWVGLPSLDVNLQQAPQTTNVMQGPSSYADAVIAAAPAVVNLYTTKMVNKGNN
PLFEDPQFRRFFGDNTPKQKRMESSLGSGVMMSPEGYILTNNHVTTGADQIVVALKDGRETIARVIGNDPETDLAVLKID
LKNLPAITIARSDSIRIGDVALAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQTDAAINPGNSGGALVDASGNLIG
INTAIFSKSGGSQGIGFAIPTKLAMDVMKSIIEHGQVIRGWLGIEVQPLTQELAESFGLKDRPGIVVAGIFRDGPAQKAG
LQLGDVILSINGEPAGDGRRSMNQVARTKPKDKIAIDVMRNGKEMRLSAEVGLRPPPAPTPVAAPE

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=331, Percent_Identity=35.6495468277946, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI22129776, Length=333, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI24308541, Length=277, Percent_Identity=33.5740072202166, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI7019477, Length=329, Percent_Identity=31.9148936170213, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1789630, Length=385, Percent_Identity=43.3766233766234, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789629, Length=307, Percent_Identity=43.9739413680782, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1786356, Length=309, Percent_Identity=43.3656957928803, Blast_Score=238, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24646839, Length=393, Percent_Identity=29.2620865139949, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 41035; Mature: 41035

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKALRFFGWPLLAGVLIAMLIIQRYPQWVGLPSLDVNLQQAPQTTNVMQGPSSYADAVI
CCCHHHHHCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHCCCCCCHHHCCCHHHHHHHH
AAAPAVVNLYTTKMVNKGNNPLFEDPQFRRFFGDNTPKQKRMESSLGSGVMMSPEGYILT
HHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCEEECCCCEEEE
NNHVTTGADQIVVALKDGRETIARVIGNDPETDLAVLKIDLKNLPAITIARSDSIRIGDV
CCCEECCCCEEEEEEECCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEE
ALAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQTDAAINPGNSGGALVDASGNLIG
EEEECCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCEEE
INTAIFSKSGGSQGIGFAIPTKLAMDVMKSIIEHGQVIRGWLGIEVQPLTQELAESFGLK
EEEEEEECCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEHHHCCEEEHHHHHHHHHCCCC
DRPGIVVAGIFRDGPAQKAGLQLGDVILSINGEPAGDGRRSMNQVARTKPKDKIAIDVMR
CCCCEEEEEEECCCCCHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEC
NGKEMRLSAEVGLRPPPAPTPVAAPE
CCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFKALRFFGWPLLAGVLIAMLIIQRYPQWVGLPSLDVNLQQAPQTTNVMQGPSSYADAVI
CCCHHHHHCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHCCCCCCHHHCCCHHHHHHHH
AAAPAVVNLYTTKMVNKGNNPLFEDPQFRRFFGDNTPKQKRMESSLGSGVMMSPEGYILT
HHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCEEECCCCEEEE
NNHVTTGADQIVVALKDGRETIARVIGNDPETDLAVLKIDLKNLPAITIARSDSIRIGDV
CCCEECCCCEEEEEEECCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCEEEEEE
ALAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQTDAAINPGNSGGALVDASGNLIG
EEEECCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCEEE
INTAIFSKSGGSQGIGFAIPTKLAMDVMKSIIEHGQVIRGWLGIEVQPLTQELAESFGLK
EEEEEEECCCCCCCCCEECHHHHHHHHHHHHHHCCCEEEHHHCCEEEHHHHHHHHHCCCC
DRPGIVVAGIFRDGPAQKAGLQLGDVILSINGEPAGDGRRSMNQVARTKPKDKIAIDVMR
CCCCEEEEEEECCCCCHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEC
NGKEMRLSAEVGLRPPPAPTPVAAPE
CCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]