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The map label for this gene is dctD [H]

Identifier: 66047222

GI number: 66047222

Start: 4755766

End: 4757100

Strand: Direct

Name: dctD [H]

Synonym: Psyr_3995

Alternate gene names: 66047222

Gene position: 4755766-4757100 (Clockwise)

Preceding gene: 66047221

Following gene: 66047223

Centisome position: 78.04

GC content: 64.19

Gene sequence:

>1335_bases
ATGTTGAATTCGGTCATCGTGGTAGACGACGAGGCGCCCATTCGGCAAGCCGTCGAACAATGGCTGACGCTGTCGGGGTT
CGAGGTGCAAGTCTTCGCCCGCGCCGAAGAGTGCCTGGCGCACCTACCGGAACACTTCCCCGGCGTCGTGCTGACCGATG
TGCGCATGCCAGGCATGAGCGGTCTGGAGCTGCTGACCCGGTTGCAAGGCGCAGACCGCGACCTGCCGGTCATCCTCCTG
ACCGGTCATGGCGATGTGCCGATGGCTGTGGAGGCGATGCGCGAAGGGGCCTATGACTTTCTGGAAAAACCCTTCAGCCC
GGAAACCCTGATCAGCAACCTGCGGCGCGCCCTCGAGAAACGCCAGTTGGTGCTGGAAAACCGCCGCCTGCATGAGCAGG
CCGATGCCAGAACCCGCCTGGACGCCACGCTGCTCGGCGTATCGCCCGGCATGCAGACACTGCGCCGCCAGGTGCTGGAA
CTGGCGCAACTGCCGGTCAATGTGATCATTCGCGGGGAAACCGGCAGCGGCAAGGAACTGGTCGCTCGCTGCCTGCATGA
TTTCGGGCCGCGCGCCGCCAGACCTTTTGTTGCACTCAACTGCGCGGCCATCCCGGAGCACCTGTTCGAAGCCGAGCTGT
TCGGCCACGAAAGCGGCGCCTTCACCGGCGCGCAGGGCAAACGCATCGGTCGTCTGGAGTATGCCGACGGCGGCACGGTG
TTCCTTGATGAAATCGAGAGCATGCCGATGGCACAGCAGGTCAAGCTGCTGCGCGTTCTGCAGGACAAGCGCCTTGAGCG
GCTGGGCTCGAATCAGAGTATCGACGTCGACCTGCGAATCATTGCCGCGACCAAGCCTGATCTTCTCGAAGAAGCGCGTG
CCGGGCGCTTCCGCGAAGATCTGGCCTATCGCCTGAACGTTGCCGAGCTGCGCCTGCCGCCGCTGCGCGAGCGTCTTGAA
GACATCGCGCAACTGTTCAGCCACTTCGCCCGCGCCGCCGCCGAACGCGTGGGCCGGGAGGCGCCCGCGCTGGATGCAGC
GCGCCTGAGCCTTTTGCTCGGCCATGACTGGCCTGGCAACGTGCGCGAGCTGGCCAATGCCGCCGAGCGGCAGGCGCTGG
GTCTGGAGCAGGCCCTGCCGCAACCTGATACTCAATGGCAGGGACATTCATTGGCGGCGCGTCAGGAAGCCTTCGAAGCA
CAATGCCTGCGCGCTTCGCTGGCCCGTCATAAAGGCGACATCAAGGCGGTGCTCAATGAGCTGCAACTGCCTCGAAGGAC
GCTGAACGAGAAGATGCAGCGCCATGCTCTGGTACGCGAAACGTTCCTCGAATGA

Upstream 100 bases:

>100_bases
CATTCATGAACTGGGCGGACAACTGACGGCGCAAAACCATGCGGACGGCGCCGAATTCTGGTTCAGCCTGCCCAACGACT
TTCTGGAGGCCTGACCCGGC

Downstream 100 bases:

>100_bases
GGGCTGCGCAGATTCCGTACAGCTTGTTCCGGCGATAACCGAACATTTCCTGCAGCGCCGGGTCTGCATACTGTTCACGG
CTATATGAGGGTCGTGATGG

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MLNSVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAHLPEHFPGVVLTDVRMPGMSGLELLTRLQGADRDLPVILL
TGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEKRQLVLENRRLHEQADARTRLDATLLGVSPGMQTLRRQVLE
LAQLPVNVIIRGETGSGKELVARCLHDFGPRAARPFVALNCAAIPEHLFEAELFGHESGAFTGAQGKRIGRLEYADGGTV
FLDEIESMPMAQQVKLLRVLQDKRLERLGSNQSIDVDLRIIAATKPDLLEEARAGRFREDLAYRLNVAELRLPPLRERLE
DIAQLFSHFARAAAERVGREAPALDAARLSLLLGHDWPGNVRELANAAERQALGLEQALPQPDTQWQGHSLAARQEAFEA
QCLRASLARHKGDIKAVLNELQLPRRTLNEKMQRHALVRETFLE

Sequences:

>Translated_444_residues
MLNSVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAHLPEHFPGVVLTDVRMPGMSGLELLTRLQGADRDLPVILL
TGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEKRQLVLENRRLHEQADARTRLDATLLGVSPGMQTLRRQVLE
LAQLPVNVIIRGETGSGKELVARCLHDFGPRAARPFVALNCAAIPEHLFEAELFGHESGAFTGAQGKRIGRLEYADGGTV
FLDEIESMPMAQQVKLLRVLQDKRLERLGSNQSIDVDLRIIAATKPDLLEEARAGRFREDLAYRLNVAELRLPPLRERLE
DIAQLFSHFARAAAERVGREAPALDAARLSLLLGHDWPGNVRELANAAERQALGLEQALPQPDTQWQGHSLAARQEAFEA
QCLRASLARHKGDIKAVLNELQLPRRTLNEKMQRHALVRETFLE
>Mature_444_residues
MLNSVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAHLPEHFPGVVLTDVRMPGMSGLELLTRLQGADRDLPVILL
TGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEKRQLVLENRRLHEQADARTRLDATLLGVSPGMQTLRRQVLE
LAQLPVNVIIRGETGSGKELVARCLHDFGPRAARPFVALNCAAIPEHLFEAELFGHESGAFTGAQGKRIGRLEYADGGTV
FLDEIESMPMAQQVKLLRVLQDKRLERLGSNQSIDVDLRIIAATKPDLLEEARAGRFREDLAYRLNVAELRLPPLRERLE
DIAQLFSHFARAAAERVGREAPALDAARLSLLLGHDWPGNVRELANAAERQALGLEQALPQPDTQWQGHSLAARQEAFEA
QCLRASLARHKGDIKAVLNELQLPRRTLNEKMQRHALVRETFLE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=369, Percent_Identity=44.4444444444444, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1790299, Length=364, Percent_Identity=45.8791208791209, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1790437, Length=441, Percent_Identity=38.7755102040816, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1788905, Length=451, Percent_Identity=38.8026607538803, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789087, Length=328, Percent_Identity=43.5975609756098, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI87082117, Length=248, Percent_Identity=48.7903225806452, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=49.7797356828194, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=43.1309904153355, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=38.006230529595, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=45.8515283842795, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1787583, Length=250, Percent_Identity=42.4, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789828, Length=249, Percent_Identity=32.1285140562249, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87081858, Length=207, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=32.7868852459016, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=30.5084745762712, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=31.3559322033898, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49579; Mature: 49579

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAHLPEHFPGVVLTDVRMPGMS
CCCCEEEECCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCH
GLELLTRLQGADRDLPVILLTGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEK
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHH
RQLVLENRRLHEQADARTRLDATLLGVSPGMQTLRRQVLELAQLPVNVIIRGETGSGKEL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHH
VARCLHDFGPRAARPFVALNCAAIPEHLFEAELFGHESGAFTGAQGKRIGRLEYADGGTV
HHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEECEEEECCCCEE
FLDEIESMPMAQQVKLLRVLQDKRLERLGSNQSIDVDLRIIAATKPDLLEEARAGRFRED
EHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHH
LAYRLNVAELRLPPLRERLEDIAQLFSHFARAAAERVGREAPALDAARLSLLLGHDWPGN
HHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
VRELANAAERQALGLEQALPQPDTQWQGHSLAARQEAFEAQCLRASLARHKGDIKAVLNE
HHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LQLPRRTLNEKMQRHALVRETFLE
HHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNSVIVVDDEAPIRQAVEQWLTLSGFEVQVFARAEECLAHLPEHFPGVVLTDVRMPGMS
CCCCEEEECCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCH
GLELLTRLQGADRDLPVILLTGHGDVPMAVEAMREGAYDFLEKPFSPETLISNLRRALEK
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHH
RQLVLENRRLHEQADARTRLDATLLGVSPGMQTLRRQVLELAQLPVNVIIRGETGSGKEL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHH
VARCLHDFGPRAARPFVALNCAAIPEHLFEAELFGHESGAFTGAQGKRIGRLEYADGGTV
HHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEECEEEECCCCEE
FLDEIESMPMAQQVKLLRVLQDKRLERLGSNQSIDVDLRIIAATKPDLLEEARAGRFRED
EHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHH
LAYRLNVAELRLPPLRERLEDIAQLFSHFARAAAERVGREAPALDAARLSLLLGHDWPGN
HHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
VRELANAAERQALGLEQALPQPDTQWQGHSLAARQEAFEAQCLRASLARHKGDIKAVLNE
HHHHHHHHHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LQLPRRTLNEKMQRHALVRETFLE
HHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]