Click here to switch to the map view.

The map label for this gene is pdxJ [H]

Identifier: 66047175

GI number: 66047175

Start: 4696247

End: 4696987

Strand: Reverse

Name: pdxJ [H]

Synonym: Psyr_3948

Alternate gene names: 66047175

Gene position: 4696987-4696247 (Counterclockwise)

Preceding gene: 66047176

Following gene: 66047170

Centisome position: 77.08

GC content: 63.83

Gene sequence:

>741_bases
GTGACCCACAGCACTCGTATCCTTCTCGGCGTGAACATCGACCACGTAGCCACCTTGCGTCAGGCCCGTGGCACGCGCTA
CCCGGACCCGGTAAAGGCTGCCCTGGATGCCGAAGAGGCAGGCGCCGACGGCATCACCGTCCACCTGCGTGAGGACCGCC
GACACATTCAGGAGCGCGATGTCCTGCTGCTCAAGGATGTCTTGCAGACCCGCATGAATTTCGAGATGGGCGTCACCGAA
GACATGCTCGCCTTCGCCGAACGCATTCGTCCGGCGCACATCTGCCTGGTGCCTGAGACACGGCAGGAGCTGACCACCGA
AGGCGGTCTGGACGTGGCGGGGCAGGAAGCGCGGATCAAGGCGGCGGTCGAGCGACTGGCGAAGATTGGCTGCGAAGTTT
CGCTGTTCATCGACGCCGACGAGCGTCAGATCGCCGCTTCAAAGCGCGTCGGCGCCCCCGCCATCGAACTGCATACCGGT
CGCTATGCCGACGCTCAGACCCCGACCGAAGTCGCCGAAGAACTGCAGCGGGTCGCCGATGGCGTAGCGTTTGGTCTCGC
CCAGGGGCTGGTCGTCAATGCCGGTCACGGCCTGCATTATCACAACGTCGAAGCCGTCGCCGCGATCAAGGGCATCAACG
AACTGAACATCGGCCACGCGCTGGTGGCTCATGCTCTGTTCGTCGGCTTCAAGGCGGCAGTGGCCGAGATGAAGGCGTTG
ATCGTGGCGGCAGCCAGATAA

Upstream 100 bases:

>100_bases
GTCGCCCTTTAGTCAGTCGTGAACTGTTTCGCAAGCCTTGATCAGGCTTTATTCTCTACAGCCTGCTTCGACCAGCTCGC
CCATTTTTCTGGAGACCACC

Downstream 100 bases:

>100_bases
CTCGTCCCTCAGGGCTTGCGCCCCACGATCACCGCACGCATGGGGGCGGGCAGGCCCTCGACTGTCTTGCTGTGATCGGT
GGGGTCCAGGTAGTCGCTCA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTHSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTE
DMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTG
RYADAQTPTEVAEELQRVADGVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKAL
IVAAAR

Sequences:

>Translated_246_residues
MTHSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTE
DMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTG
RYADAQTPTEVAEELQRVADGVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKAL
IVAAAR
>Mature_245_residues
THSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTED
MLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTGR
YADAQTPTEVAEELQRVADGVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALI
VAAAR

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=238, Percent_Identity=64.2857142857143, Blast_Score=305, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26579; Mature: 26448

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERD
CCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCEEEEEEHHHHHHHHHH
VLLLKDVLQTRMNFEMGVTEDMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCHHHHH
AAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTGRYADAQTPTEVAEELQRVAD
HHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
GVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKAL
HHHHHHHCCEEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVAAAR
HHHCCC
>Mature Secondary Structure 
THSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERD
CCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHCHHHCCCCCEEEEEEHHHHHHHHHH
VLLLKDVLQTRMNFEMGVTEDMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCHHHHH
AAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTGRYADAQTPTEVAEELQRVAD
HHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
GVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKAL
HHHHHHHCCEEEECCCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVAAAR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA