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The map label for this gene is actP [H]

Identifier: 66046984

GI number: 66046984

Start: 4472506

End: 4474164

Strand: Reverse

Name: actP [H]

Synonym: Psyr_3756

Alternate gene names: 66046984

Gene position: 4474164-4472506 (Counterclockwise)

Preceding gene: 66046985

Following gene: 66046982

Centisome position: 73.42

GC content: 58.71

Gene sequence:

>1659_bases
ATGATCCGGCGCCTATCAGCAGCACTTGGCCTGGCCGCCTTCGCGCCGACCCTCTGGGCGGCAGACGCGTTGACGGGTGC
AGTGCAGAAACAACCCCTGAACGTCGCCGCGATCGTCATGTTCGTGGTCTTCGTCGCTTTCACGCTGTACATCACCTACT
GGGCATCGAAAAAGAACAAGACAGCGTCGGACTATTACTCGGCAGGTGGCAAGATCACCGGCTTCCAGAACGGTCTGGCG
ATCGCCGGTGACTACATGTCGGCAGCGTCCTTTCTGGGTATTTCCGCGCTGGTCTACACCTCCGGCTACGATGGCCTGAT
CTACTCGATCGGCTTCCTGGTAGGCTGGCCGATCATCCTGTTCCTGATCGCCGAACGCCTGCGCAACCTGGGTAAATACA
CCTTTGCCGATGTGGCGTCGTACCGCCTCAAGCAAAAGGAAATTCGCACCCTGTCTGCCTGCGGCTCACTGGTGGTGGTG
GCGTTTTACCTGATTGCGCAGATGGTCGGTGCCGGCAAGCTGATCCAGTTGCTGTTCGGTCTGGACTACGCCGTTGCGGT
GGTGCTGGTCGGTATCCTGATGTGCCTCTATGTGCTGTTCGGCGGCATGCTCGCTACCACCTGGGTGCAGATCATCAAGG
CGGTGATGTTGCTGTCCGGTGCGTCGTTCATGGCATTGATGGTCATGAAGCACGTCAACTTCGACTTCAACATGCTGTTC
TCCGAAGCGATCAAGGTTCACCCCAAAGGTGAAGCGATCATGAGCCCTGGCGGGCTGGTGAAAGACCCGATCTCGGCGTT
CTCGCTGGGTCTGGCCCTGATGTTCGGTACTGCGGGCCTGCCACACATCCTGATGCGCTTCTTCACCGTGAGCGATGCCA
AGGAAGCGCGCAAGTCGGTGCTCTACGCAACCGGCTTTATCGGTTACTTCTACATCCTGACCTTCATCATCGGTTTCGGC
GCGATCCTGCTGGTCAGCACCAATCCGGCGTTCAAGGATGCAGCAGGCGCCTTGTTGGGCGGTAACAACATGGCTGCGGT
TCACCTGGCCGATGCGGTCGGTGGCAGTCTGTTCCTGGGCTTCATCTCGGCAGTCGCTTTCGCCACCATTCTGGCAGTGG
TTGCCGGTCTGACCCTGGCGGGTGCTTCGGCGGTTTCCCACGACTTGTATGCCAGCGTCATCAAGGCAGGCAAAGCCAAC
GAGAAGGACGAGATCCGTATCTCGAAAATCACCACCATTGCCCTGGCGGTCGTGGCGATCTTTCTGGGTATTGCCTTTGA
AAGCCAGAACATCGCCTTCATGGTGGGCCTGGCGTTCTCGGTCGCGGCAAGCTGCAACTTCCCGATTCTGCTGCTTTCCA
TGTACTGGAAAAACCTGACCACCCGTGGCGCCATGATCGGCGGCTGGATGGGCCTGATCAGTGCAGTGGTGCTGATGGTG
CTCGGTCCGACCATCTGGGTGCAGATCCTGCACCACGAGAAAGCCATTTTCCCTTACGAATACCCGGCGCTGTTTTCCAT
CGCCATCGCCTTCGTAGGTATCTGGTTCTTCTCCATCACCGACAAGTCGAAAGCGGCGGAGGGCGAGCGCGCTCTGTTCT
ATCCGCAATTCGTCCGCTCGCAGACGGGGCTGGGTGCCAGTGGTGCGGTTTCGCACTAA

Upstream 100 bases:

>100_bases
GGCTGATCCTTTCCGCGTTCATATTGACGGCCATCTATGTTCGCCGTGCCAACGGTGAATTCGATGACCTGAACAACGCG
ATCCTCAAGGAGGCTCAGCA

Downstream 100 bases:

>100_bases
GGTACCGGTGTTGTGAACGAAGCAGCCTTCGGGCTGCTTTTTCATGAGCGATAAAAAAACCCCGCTTGAAAAAGCGGGGT
TTTTTATTGGCTATATGCGC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MIRRLSAALGLAAFAPTLWAADALTGAVQKQPLNVAAIVMFVVFVAFTLYITYWASKKNKTASDYYSAGGKITGFQNGLA
IAGDYMSAASFLGISALVYTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLKQKEIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYAVAVVLVGILMCLYVLFGGMLATTWVQIIKAVMLLSGASFMALMVMKHVNFDFNMLF
SEAIKVHPKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKAGKAN
EKDEIRISKITTIALAVVAIFLGIAFESQNIAFMVGLAFSVAASCNFPILLLSMYWKNLTTRGAMIGGWMGLISAVVLMV
LGPTIWVQILHHEKAIFPYEYPALFSIAIAFVGIWFFSITDKSKAAEGERALFYPQFVRSQTGLGASGAVSH

Sequences:

>Translated_552_residues
MIRRLSAALGLAAFAPTLWAADALTGAVQKQPLNVAAIVMFVVFVAFTLYITYWASKKNKTASDYYSAGGKITGFQNGLA
IAGDYMSAASFLGISALVYTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLKQKEIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYAVAVVLVGILMCLYVLFGGMLATTWVQIIKAVMLLSGASFMALMVMKHVNFDFNMLF
SEAIKVHPKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKAGKAN
EKDEIRISKITTIALAVVAIFLGIAFESQNIAFMVGLAFSVAASCNFPILLLSMYWKNLTTRGAMIGGWMGLISAVVLMV
LGPTIWVQILHHEKAIFPYEYPALFSIAIAFVGIWFFSITDKSKAAEGERALFYPQFVRSQTGLGASGAVSH
>Mature_552_residues
MIRRLSAALGLAAFAPTLWAADALTGAVQKQPLNVAAIVMFVVFVAFTLYITYWASKKNKTASDYYSAGGKITGFQNGLA
IAGDYMSAASFLGISALVYTSGYDGLIYSIGFLVGWPIILFLIAERLRNLGKYTFADVASYRLKQKEIRTLSACGSLVVV
AFYLIAQMVGAGKLIQLLFGLDYAVAVVLVGILMCLYVLFGGMLATTWVQIIKAVMLLSGASFMALMVMKHVNFDFNMLF
SEAIKVHPKGEAIMSPGGLVKDPISAFSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVLYATGFIGYFYILTFIIGFG
AILLVSTNPAFKDAAGALLGGNNMAAVHLADAVGGSLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKAGKAN
EKDEIRISKITTIALAVVAIFLGIAFESQNIAFMVGLAFSVAASCNFPILLLSMYWKNLTTRGAMIGGWMGLISAVVLMV
LGPTIWVQILHHEKAIFPYEYPALFSIAIAFVGIWFFSITDKSKAAEGERALFYPQFVRSQTGLGASGAVSH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=453, Percent_Identity=24.5033112582781, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1790503, Length=552, Percent_Identity=78.2608695652174, Blast_Score=866, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=457, Percent_Identity=25.164113785558, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87082237, Length=453, Percent_Identity=21.1920529801325, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58872; Mature: 58872

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA