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The map label for this gene is fic [H]

Identifier: 66046949

GI number: 66046949

Start: 4408636

End: 4409241

Strand: Direct

Name: fic [H]

Synonym: Psyr_3720

Alternate gene names: 66046949

Gene position: 4408636-4409241 (Clockwise)

Preceding gene: 66046948

Following gene: 66046950

Centisome position: 72.35

GC content: 50.33

Gene sequence:

>606_bases
ATGCTCGATAAATATGGGGCCAACCAGGATCCATACTGCTATCCCGGCACGTCTATTTTGAAAAACCGCTTGAACTTGAC
TAGCGATGATCTACTGTCAGGCGCGGAGCGCGCACTGTCTGAAGTCGCTTTGAGTCTAATCGAGTTTGCACCGCCTCCAT
ACGATCTCTCGTACCTGAAATACCTCCATCGCCTTCTGTTCGCCGATCTTTACGACTGGGCGGGAGAGCTACGCACTGTA
GACATATCCAAAGGGAATACCCGTTTCTGCACCACAACCCGCATCGAGCCTGAGGCGAAAAAAATATTTGCTCCTCTCGC
TAGCGTAAACTGGCTTCAAGAGCTGGAACGAGAACAGCTTGTAAACGCCAGCGCCGAAGCTTTCGGTGATCTGAATGTCA
TTCATCCCTTCAGAGAGGGCAATGGCAGGGCCCAGCGAGTATTGTTCGAACATCTCATCATGAACGCAGGATACGAAATC
AGCTGGTGGGCAGTAGAAGCAGAGGAATGGATGCAAGCGAATATCTATGCGGTGGATTGCGAATATGGTCCGCTTATAGA
CGTGTTTGAGCACTGTATCGGAAAGCCTATCTTGCCAGAAACCTGA

Upstream 100 bases:

>100_bases
GCTTGCGCTTGGAGGGTTATGACTGCACGCCGCTCGACGCCGAGCGTCCTCTTCCGACTCGCGAAGAGCTGTTGAAAACT
TACCGTAACAAACAGGCCTG

Downstream 100 bases:

>100_bases
ACCATTCATCGATTCACGTGTTAAATCTGCAGCCAAATTTAGCGCTGAAGCCGATCATCAATCCTCCCTTCAATGGCCTG
ATCACGCCAAGAAGCCCAGT

Product: filamentation induced by cAMP protein Fic

Products: NA

Alternate protein names: Cell filamentation protein fic [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLDKYGANQDPYCYPGTSILKNRLNLTSDDLLSGAERALSEVALSLIEFAPPPYDLSYLKYLHRLLFADLYDWAGELRTV
DISKGNTRFCTTTRIEPEAKKIFAPLASVNWLQELEREQLVNASAEAFGDLNVIHPFREGNGRAQRVLFEHLIMNAGYEI
SWWAVEAEEWMQANIYAVDCEYGPLIDVFEHCIGKPILPET

Sequences:

>Translated_201_residues
MLDKYGANQDPYCYPGTSILKNRLNLTSDDLLSGAERALSEVALSLIEFAPPPYDLSYLKYLHRLLFADLYDWAGELRTV
DISKGNTRFCTTTRIEPEAKKIFAPLASVNWLQELEREQLVNASAEAFGDLNVIHPFREGNGRAQRVLFEHLIMNAGYEI
SWWAVEAEEWMQANIYAVDCEYGPLIDVFEHCIGKPILPET
>Mature_201_residues
MLDKYGANQDPYCYPGTSILKNRLNLTSDDLLSGAERALSEVALSLIEFAPPPYDLSYLKYLHRLLFADLYDWAGELRTV
DISKGNTRFCTTTRIEPEAKKIFAPLASVNWLQELEREQLVNASAEAFGDLNVIHPFREGNGRAQRVLFEHLIMNAGYEI
SWWAVEAEEWMQANIYAVDCEYGPLIDVFEHCIGKPILPET

Specific function: Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Involved in cell filamentation induced by cyclic AMP. May have some role in cell division [H]

COG id: COG2184

COG function: function code D; Protein involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fido domain [H]

Homologues:

Organism=Escherichia coli, GI1789761, Length=174, Percent_Identity=41.9540229885057, Blast_Score=157, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003812 [H]

Pfam domain/function: PF02661 Fic [H]

EC number: NA

Molecular weight: Translated: 22878; Mature: 22878

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKYGANQDPYCYPGTSILKNRLNLTSDDLLSGAERALSEVALSLIEFAPPPYDLSYLK
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
YLHRLLFADLYDWAGELRTVDISKGNTRFCTTTRIEPEAKKIFAPLASVNWLQELEREQL
HHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNASAEAFGDLNVIHPFREGNGRAQRVLFEHLIMNAGYEISWWAVEAEEWMQANIYAVDC
HCHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCEEEEEC
EYGPLIDVFEHCIGKPILPET
CCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLDKYGANQDPYCYPGTSILKNRLNLTSDDLLSGAERALSEVALSLIEFAPPPYDLSYLK
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
YLHRLLFADLYDWAGELRTVDISKGNTRFCTTTRIEPEAKKIFAPLASVNWLQELEREQL
HHHHHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNASAEAFGDLNVIHPFREGNGRAQRVLFEHLIMNAGYEISWWAVEAEEWMQANIYAVDC
HCHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHCCEEEEEC
EYGPLIDVFEHCIGKPILPET
CCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546924; 2403545; 9278503; 7549107; 2007139 [H]