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The map label for this gene is gpwA [H]

Identifier: 66046899

GI number: 66046899

Start: 4357067

End: 4357621

Strand: Reverse

Name: gpwA [H]

Synonym: Psyr_3670

Alternate gene names: 66046899

Gene position: 4357621-4357067 (Counterclockwise)

Preceding gene: 66046900

Following gene: 66046895

Centisome position: 71.51

GC content: 58.02

Gene sequence:

>555_bases
ATGATGAAACTTCGCTTTTTTTCGATCCCTCTTTTGCTGCTGGCCATGAGCGGTGCTGCCATGGCTGCCGACTGCCCGCC
GTTGCTGCAAGGCGAGTTGCCCAAGCTGCGCGCCAAGGAAAACATCGACCTGTGCAAGCGCTTCGCCGGCAAGCCGCTGG
TGGTGGTCAATACTGCCAGTTTCTGCGGCTTTGCCCCGCAGTTCAAAGGCCTTGAAGCGCTGAGTCAGCGCTACAAGGGG
CAGGGGCTGGAGGTGTTGGGCGTGCCGTCCAATGACTTCAAACAGGAAGCCAAGGATGGTGAGGAGACCGCCAAGGTCTG
TTACGTCAACTATGGCGTGACCTTCACCATGACCGAGCCGCAGGCAGTACGCGGTGATGATGCGACCCATCTGTTCAAGG
TACTGGCCGAGCAGAGCAGTGCGCCGCGCTGGAACTTTTACAAGTACGTGGTTGATCGTCAGGGCAAGGTCATCGCCAAC
TTCTCCAGCATGACCAAGCCGGATGATCCGGAGCTGATCGCAGCCATTGAGAAGGCGATTGCGTCTAAGCCTTAG

Upstream 100 bases:

>100_bases
GTCGGGCTGGCCGCATTGCAACTGGGAATGGGCGCTTGCTAGGCAGACGCTCCGGCATGCGGTAGCGTGTCGGCAGACGA
CAACAATATCCAGGGCCGCC

Downstream 100 bases:

>100_bases
GGGGCAAAAAAGGGCGGCTTGAGTCTTGTCTGAATCGACCTGGCATCGCAGAACCCTTGTGTGACGCAGAGCGCCACATA
GAGGACGCAGAGCGTCCAGA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MMKLRFFSIPLLLLAMSGAAMAADCPPLLQGELPKLRAKENIDLCKRFAGKPLVVVNTASFCGFAPQFKGLEALSQRYKG
QGLEVLGVPSNDFKQEAKDGEETAKVCYVNYGVTFTMTEPQAVRGDDATHLFKVLAEQSSAPRWNFYKYVVDRQGKVIAN
FSSMTKPDDPELIAAIEKAIASKP

Sequences:

>Translated_184_residues
MMKLRFFSIPLLLLAMSGAAMAADCPPLLQGELPKLRAKENIDLCKRFAGKPLVVVNTASFCGFAPQFKGLEALSQRYKG
QGLEVLGVPSNDFKQEAKDGEETAKVCYVNYGVTFTMTEPQAVRGDDATHLFKVLAEQSSAPRWNFYKYVVDRQGKVIAN
FSSMTKPDDPELIAAIEKAIASKP
>Mature_184_residues
MMKLRFFSIPLLLLAMSGAAMAADCPPLLQGELPKLRAKENIDLCKRFAGKPLVVVNTASFCGFAPQFKGLEALSQRYKG
QGLEVLGVPSNDFKQEAKDGEETAKVCYVNYGVTFTMTEPQAVRGDDATHLFKVLAEQSSAPRWNFYKYVVDRQGKVIAN
FSSMTKPDDPELIAAIEKAIASKP

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=143, Percent_Identity=33.5664335664336, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI192455698, Length=140, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1788003, Length=162, Percent_Identity=34.5679012345679, Blast_Score=90, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17535473, Length=144, Percent_Identity=34.0277777777778, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506887, Length=143, Percent_Identity=33.5664335664336, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=128, Percent_Identity=43.75, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319721, Length=141, Percent_Identity=39.7163120567376, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322826, Length=142, Percent_Identity=38.0281690140845, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI85726443, Length=136, Percent_Identity=34.5588235294118, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656772, Length=135, Percent_Identity=31.8518518518519, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656777, Length=135, Percent_Identity=31.8518518518519, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24656767, Length=135, Percent_Identity=31.8518518518519, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20212; Mature: 20212

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLRFFSIPLLLLAMSGAAMAADCPPLLQGELPKLRAKENIDLCKRFAGKPLVVVNTAS
CCEEEHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECHH
FCGFAPQFKGLEALSQRYKGQGLEVLGVPSNDFKQEAKDGEETAKVCYVNYGVTFTMTEP
HHCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEEECCEEEEECCC
QAVRGDDATHLFKVLAEQSSAPRWNFYKYVVDRQGKVIANFSSMTKPDDPELIAAIEKAI
CCCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHHH
ASKP
CCCC
>Mature Secondary Structure
MMKLRFFSIPLLLLAMSGAAMAADCPPLLQGELPKLRAKENIDLCKRFAGKPLVVVNTAS
CCEEEHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECHH
FCGFAPQFKGLEALSQRYKGQGLEVLGVPSNDFKQEAKDGEETAKVCYVNYGVTFTMTEP
HHCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCEEEEEEECCEEEEECCC
QAVRGDDATHLFKVLAEQSSAPRWNFYKYVVDRQGKVIANFSSMTKPDDPELIAAIEKAI
CCCCCCCHHHHHHHHHHHCCCCCCHHHHEEECCCCCEEECCCCCCCCCCHHHHHHHHHHH
ASKP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA