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The map label for this gene is yciK [H]

Identifier: 66046881

GI number: 66046881

Start: 4337619

End: 4338359

Strand: Direct

Name: yciK [H]

Synonym: Psyr_3652

Alternate gene names: 66046881

Gene position: 4337619-4338359 (Clockwise)

Preceding gene: 66046880

Following gene: 66046882

Centisome position: 71.18

GC content: 62.62

Gene sequence:

>741_bases
ATGTTTGATTACTCCGCGCACCCGGAACTGCTCAAGGGCCGGATCATTCTGGTCACCGGTGCCGCTCGCGGCATCGGTGC
CGCAGCCGCCAAAGCCTACGCAGCGCATGGCGCCACCGTCTTGCTGCTGGGCAGGACCGACGCCAGCCTGGCTCAGGTTC
ATGACGAGATAAAGGCAGCAGGTCAGTTGCCGCCACTGGTCATACCCTTCGATCTGCAAAGCGCCGACCCGGCGCAGTAC
CACGCGCTGGCGGCCATGATCGAGCGCACAGTCGGCCGTCTAGACGGGCTGCTGCATAACGCCTCGATCATCGGCCCGCG
TACCTCGGTGGAACACCTGCCCGGCGAAGACTTCATGCAGGTCATGCACGTCAACGTCAACGCCACCTTCATGCTCACCC
AGGCACTGCTGCCGCTGCTTCAGCGTTCGGCGGATGCGTCGATAGCCTTCACCTCCAGCAGCGTAGGTCGCAAGGGGCGC
GCACAATGGGGCGCTTACGGCGTGTCGAAGTTTGCCACCGAAGGCCTGATGCAAACCCTTGCTGACGAGCTGGAGGGCGT
CAGCACGGTCCGCGCCAACAGCATCAACCCTGGCGCAACCCGCACAGGCATGCGCGCGCAGGCCTATCCGGATGAAAATC
CACAGAACAATCCGGCGCCTGAAGAGATCATGCCGGTCTATCTGTACCTGATGGGGCCGGACAGCAAATGCATCAATGGG
CAGGCATTGAATGCCCAGTGA

Upstream 100 bases:

>100_bases
CAATCCCGATCACTGGGGTGCCGACGTGGTGGTCGATCATCCGCTGGAATTGCGCAAGGTGCTGGATAACGCACTGTGCA
GCTGCTAAACGAGGCTTTAC

Downstream 100 bases:

>100_bases
CAGGGACAGGCTGTTGTGACGAAAAACCGTCACAACGGCCGTTCAAAACGGCTTTTTAAGTCAAGGAATTGCCGATTTTT
CGCCACTGTCAGAGAGATGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAAGQLPPLVIPFDLQSADPAQY
HALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQVMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGR
AQWGAYGVSKFATEGLMQTLADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
QALNAQ

Sequences:

>Translated_246_residues
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAAGQLPPLVIPFDLQSADPAQY
HALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQVMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGR
AQWGAYGVSKFATEGLMQTLADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
QALNAQ
>Mature_246_residues
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAAGQLPPLVIPFDLQSADPAQY
HALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQVMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGR
AQWGAYGVSKFATEGLMQTLADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
QALNAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=26.3358778625954, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=203, Percent_Identity=30.0492610837438, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19743808, Length=221, Percent_Identity=28.9592760180996, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=29.6, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=24.2798353909465, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32455239, Length=228, Percent_Identity=30.2631578947368, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031765, Length=228, Percent_Identity=30.2631578947368, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787526, Length=243, Percent_Identity=51.440329218107, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI87082100, Length=216, Percent_Identity=31.0185185185185, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=207, Percent_Identity=29.4685990338164, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=27.0916334661355, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=30.2040816326531, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=27.6859504132231, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=224, Percent_Identity=29.4642857142857, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=27.0161290322581, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=209, Percent_Identity=31.1004784688995, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=215, Percent_Identity=26.046511627907, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=205, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=26.530612244898, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=220, Percent_Identity=28.1818181818182, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=227, Percent_Identity=25.1101321585903, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=208, Percent_Identity=30.2884615384615, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=205, Percent_Identity=25.3658536585366, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=28.1124497991968, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=210, Percent_Identity=30.952380952381, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=238, Percent_Identity=28.9915966386555, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=214, Percent_Identity=24.7663551401869, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=205, Percent_Identity=34.6341463414634, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=33.7448559670782, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=33.1683168316832, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644339, Length=203, Percent_Identity=33.0049261083744, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357041, Length=205, Percent_Identity=33.1707317073171, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=30.4568527918782, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553409, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647948, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647946, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26116; Mature: 26116

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAA
CCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
GQLPPLVIPFDLQSADPAQYHALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHH
VMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGRAQWGAYGVSKFATEGLMQTL
HHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
HHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCC
QALNAQ
EECCCC
>Mature Secondary Structure
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAA
CCCCCCCHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
GQLPPLVIPFDLQSADPAQYHALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHH
VMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGRAQWGAYGVSKFATEGLMQTL
HHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
HHHHHCCCEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCC
QALNAQ
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]