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The map label for this gene is htpX [H]

Identifier: 66046845

GI number: 66046845

Start: 4300383

End: 4301270

Strand: Direct

Name: htpX [H]

Synonym: Psyr_3616

Alternate gene names: 66046845

Gene position: 4300383-4301270 (Clockwise)

Preceding gene: 66046844

Following gene: 66046847

Centisome position: 70.57

GC content: 59.91

Gene sequence:

>888_bases
ATGATGCGCATTTTGCTGTTTTTGGCCACTAACCTTGCGGTCGTGCTGATTGCCAGCATCACCCTGAGCCTTTTTGGCTT
CAATGGGTTCATGGCGGCCAACGGGGTTGATCTGAACCTCAATCAGCTGCTGGTCTTCTGCGCTGTGTTCGGCTTCGCGG
GCTCGCTGTTCTCGCTGTTCATCTCCAAGTGGATGGCGAAGATGAGCACCGGTACTCAGATCATCAGCCAGCCTCGCACT
CGCCATGAGCAATGGTTGCTGCAGACCGTTGAACAATTGTCCCGCGACGCGGGCATCAAGATGCCGGAGGTCGGTATTTT
CCCGGCGTACGAAGCCAACGCGTTCGCTACGGGCTGGAACAAGAACGATGCACTGGTTGCGGTCAGCCAGGGCCTGCTCG
AGCGTTTTTCGCCGGATGAGGTGAAAGCCGTACTGGCGCACGAGATCGGCCACGTTGCCAACGGCGACATGGTGACGCTG
GCGCTGGTGCAGGGTGTGGTGAACACCTTCGTGATGTTCTTCGCCCGCATCATCGGCAACTTCGTCGACAAGGTGATCTT
CAAGACTGAAAACGGTCAGGGCATCGCTTACTACATCACGACGATCTTCGCCGAGCTGGTACTGGGCTTTCTGGCCAGCG
CCATCGTCATGTGGTTCTCGCGCAAACGCGAATTCCGCGCTGACGATGCCGGTGCACGACTGGCGGGTACGGGTGCAATG
ATCGGCGCGCTGCAACGCCTGCGTTCCGAACAGGGCGTCCCGGTGAACATGCCCGACAGCCTGACCGCCTTCGGTATCAA
CGCCGGTCTCAAGAAAGGCCTCGCCGGCCTGTTCATGAGCCACCCGCCGCTGGAGCAACGCATCGAGGCCCTGCGCCGCC
GCGGTTGA

Upstream 100 bases:

>100_bases
AGGACACAGTTTGAAATAGTCCCTCTGTTGAATAGCAGCAAGCATCACCTTATATACCCGGCATCGAGTTACATATTTAC
CTGAGGAGAACGTTTCGACC

Downstream 100 bases:

>100_bases
ACCACGAACGCGATAGCCTCAGCCCCGCGCATGGCAATGAGAGGTGTTCTTCCGGACACCTCTCGTTCCTTACGCTCCGC
GTGGGAATGCAGTTCGTGAC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIISQPRT
RHEQWLLQTVEQLSRDAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTL
ALVQGVVNTFVMFFARIIGNFVDKVIFKTENGQGIAYYITTIFAELVLGFLASAIVMWFSRKREFRADDAGARLAGTGAM
IGALQRLRSEQGVPVNMPDSLTAFGINAGLKKGLAGLFMSHPPLEQRIEALRRRG

Sequences:

>Translated_295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIISQPRT
RHEQWLLQTVEQLSRDAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTL
ALVQGVVNTFVMFFARIIGNFVDKVIFKTENGQGIAYYITTIFAELVLGFLASAIVMWFSRKREFRADDAGARLAGTGAM
IGALQRLRSEQGVPVNMPDSLTAFGINAGLKKGLAGLFMSHPPLEQRIEALRRRG
>Mature_295_residues
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLFISKWMAKMSTGTQIISQPRT
RHEQWLLQTVEQLSRDAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTL
ALVQGVVNTFVMFFARIIGNFVDKVIFKTENGQGIAYYITTIFAELVLGFLASAIVMWFSRKREFRADDAGARLAGTGAM
IGALQRLRSEQGVPVNMPDSLTAFGINAGLKKGLAGLFMSHPPLEQRIEALRRRG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=298, Percent_Identity=48.3221476510067, Blast_Score=266, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 32227; Mature: 32227

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISKWMAKMSTGTQIISQPRTRHEQWLLQTVEQLSRDAGIKMPEVGIFPAYEANAFATGWN
HHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALVQGVVNTFVMFFARIIGN
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDKVIFKTENGQGIAYYITTIFAELVLGFLASAIVMWFSRKREFRADDAGARLAGTGAM
HHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
IGALQRLRSEQGVPVNMPDSLTAFGINAGLKKGLAGLFMSHPPLEQRIEALRRRG
HHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLF
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
ISKWMAKMSTGTQIISQPRTRHEQWLLQTVEQLSRDAGIKMPEVGIFPAYEANAFATGWN
HHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCC
KNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALVQGVVNTFVMFFARIIGN
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVDKVIFKTENGQGIAYYITTIFAELVLGFLASAIVMWFSRKREFRADDAGARLAGTGAM
HHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
IGALQRLRSEQGVPVNMPDSLTAFGINAGLKKGLAGLFMSHPPLEQRIEALRRRG
HHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA