Click here to switch to the map view.

The map label for this gene is ydbM [H]

Identifier: 66046833

GI number: 66046833

Start: 4285891

End: 4287072

Strand: Direct

Name: ydbM [H]

Synonym: Psyr_3604

Alternate gene names: 66046833

Gene position: 4285891-4287072 (Clockwise)

Preceding gene: 66046832

Following gene: 66046837

Centisome position: 70.33

GC content: 65.14

Gene sequence:

>1182_bases
ATGAAACTTTCACCGCTTCGTCAGCACCGTGAGCTGTCCGAATCAGCAGCAGATTTCGCCACCCGGCTGGAAGGGATTAC
CGCAACGCTGGCCGAAACCGCAGAGCACTACGATGCCAGCGGAGCATTCCCCCACGCCAACTTTGCCTTGCTGCACAGCC
ATGGCCTGCTGGGCTTTACCGTGCCCGCCGAACTGGGCGGCGGCGGTGCCGATCTGGCGCGAGCGCAACAGGTCGTCAGC
GCAGTGGCCAGGGGCGAACCGTCGACAGCGCTGATTCTGGTGATGCAGTACCTGCAGCATTCGCGCCTGCAAGAGAACAG
CCAATGGCCGACTGATCTGCGCATTCGCGTGGCCGAAGAGGCGGTTCGCGACGGCGCGCTGATCAACGCCCTGCGCGTGG
AGCCGGACCTGGGCACACCCGCACGCGGCGGCCTGCCGGGCACCATCGCCTGCCGTACCGCCGAGGGCTGGCGGATCAGC
GGCAGCAAAATCTACTCCACCGGCAGCCATGGCCTGACCTGGTTTGCCGTGTGGGCTCGCAGCGATGACGACGACCCGTT
GGTCGGCAGCTGGCTGGTGCACAAGGACACGCCCGGCATCACGATCATCGAGGACTGGGACCATCTGGGCATGCGCGCCA
CCAGCAGCCACGAAGTCAGATTCGACAATGTGCTGGTGCCGCTCGATCACGCCGTCAGCGTCAGCCCGTGGAGCGCTCCG
CAATCCGAACTGGATGGATCGGGCCTGCTGTGGATGGCGGTGCTGCTGTCGTCGGTCTACGACGGCATCGCTCAATCCGC
CCGCGACTGGCTGGTGCACTGGCTGGAACAGCGCACGCCCTCCAACCTCGGCGCGTCGCTATCGACCTTGCCGCGCTTTC
AGGAAACCGTCGGGCAGATCGATACCCTGCTGTTCGCCAATCGCACCCTGCTGCACTCGGCTGCCCACGGGCACACACCT
GCCCAGCACGCCGGGCAGATCAAATACCTGGTGACGGGCAACGCCATCCGCGCGGTGGAGCTGGCCATCGAGGCTTCGGG
GAATCCTGGACTGTCACGCAGCAACCCGTTGCAGCGCCACTACCGCAACGTCCTGTGCGGTCGGGTGCATACCCCACAGA
ACGATGCGGTGCTGGTGAACGTGGGCAAGGCGGCGTTTGCAGCACGCAGCAAAGACCAATAA

Upstream 100 bases:

>100_bases
TCTCGACCGGCTTCGATAAAAGCTTCAACACATCGCGTGCCCGGATTGCCCAGGCCAACGCTCACTAACCCTCGGATATC
CGCTGCGAAAAGGACCCCGC

Downstream 100 bases:

>100_bases
GACGCGTCAGAGCAGTGACGGCGGCTCGAACGCCGTCACCGGCGGCAGGTCCTGATGCCATTTGACGATGTCCACCGATG
CTGTCTGTGCTGAACAGCCC

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLSPLRQHRELSESAADFATRLEGITATLAETAEHYDASGAFPHANFALLHSHGLLGFTVPAELGGGGADLARAQQVVS
AVARGEPSTALILVMQYLQHSRLQENSQWPTDLRIRVAEEAVRDGALINALRVEPDLGTPARGGLPGTIACRTAEGWRIS
GSKIYSTGSHGLTWFAVWARSDDDDPLVGSWLVHKDTPGITIIEDWDHLGMRATSSHEVRFDNVLVPLDHAVSVSPWSAP
QSELDGSGLLWMAVLLSSVYDGIAQSARDWLVHWLEQRTPSNLGASLSTLPRFQETVGQIDTLLFANRTLLHSAAHGHTP
AQHAGQIKYLVTGNAIRAVELAIEASGNPGLSRSNPLQRHYRNVLCGRVHTPQNDAVLVNVGKAAFAARSKDQ

Sequences:

>Translated_393_residues
MKLSPLRQHRELSESAADFATRLEGITATLAETAEHYDASGAFPHANFALLHSHGLLGFTVPAELGGGGADLARAQQVVS
AVARGEPSTALILVMQYLQHSRLQENSQWPTDLRIRVAEEAVRDGALINALRVEPDLGTPARGGLPGTIACRTAEGWRIS
GSKIYSTGSHGLTWFAVWARSDDDDPLVGSWLVHKDTPGITIIEDWDHLGMRATSSHEVRFDNVLVPLDHAVSVSPWSAP
QSELDGSGLLWMAVLLSSVYDGIAQSARDWLVHWLEQRTPSNLGASLSTLPRFQETVGQIDTLLFANRTLLHSAAHGHTP
AQHAGQIKYLVTGNAIRAVELAIEASGNPGLSRSNPLQRHYRNVLCGRVHTPQNDAVLVNVGKAAFAARSKDQ
>Mature_393_residues
MKLSPLRQHRELSESAADFATRLEGITATLAETAEHYDASGAFPHANFALLHSHGLLGFTVPAELGGGGADLARAQQVVS
AVARGEPSTALILVMQYLQHSRLQENSQWPTDLRIRVAEEAVRDGALINALRVEPDLGTPARGGLPGTIACRTAEGWRIS
GSKIYSTGSHGLTWFAVWARSDDDDPLVGSWLVHKDTPGITIIEDWDHLGMRATSSHEVRFDNVLVPLDHAVSVSPWSAP
QSELDGSGLLWMAVLLSSVYDGIAQSARDWLVHWLEQRTPSNLGASLSTLPRFQETVGQIDTLLFANRTLLHSAAHGHTP
AQHAGQIKYLVTGNAIRAVELAIEASGNPGLSRSNPLQRHYRNVLCGRVHTPQNDAVLVNVGKAAFAARSKDQ

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=25.2659574468085, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501859, Length=356, Percent_Identity=23.5955056179775, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=342, Percent_Identity=23.6842105263158, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=271, Percent_Identity=23.9852398523985, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666513, Length=350, Percent_Identity=23.7142857142857, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646207, Length=394, Percent_Identity=24.8730964467005, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42478; Mature: 42478

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSPLRQHRELSESAADFATRLEGITATLAETAEHYDASGAFPHANFALLHSHGLLGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEE
VPAELGGGGADLARAQQVVSAVARGEPSTALILVMQYLQHSRLQENSQWPTDLRIRVAEE
CCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHH
AVRDGALINALRVEPDLGTPARGGLPGTIACRTAEGWRISGSKIYSTGSHGLTWFAVWAR
HHHCCHHEEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCCEEEECCCCCEEEEEEEEC
SDDDDPLVGSWLVHKDTPGITIIEDWDHLGMRATSSHEVRFDNVLVPLDHAVSVSPWSAP
CCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEECCEEEECCCCEECCCCCCC
QSELDGSGLLWMAVLLSSVYDGIAQSARDWLVHWLEQRTPSNLGASLSTLPRFQETVGQI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
DTLLFANRTLLHSAAHGHTPAQHAGQIKYLVTGNAIRAVELAIEASGNPGLSRSNPLQRH
HHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCHHHHH
YRNVLCGRVHTPQNDAVLVNVGKAAFAARSKDQ
HHHHHHCCCCCCCCCEEEEEECHHHHHHCCCCC
>Mature Secondary Structure
MKLSPLRQHRELSESAADFATRLEGITATLAETAEHYDASGAFPHANFALLHSHGLLGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEE
VPAELGGGGADLARAQQVVSAVARGEPSTALILVMQYLQHSRLQENSQWPTDLRIRVAEE
CCHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHH
AVRDGALINALRVEPDLGTPARGGLPGTIACRTAEGWRISGSKIYSTGSHGLTWFAVWAR
HHHCCHHEEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCCEEEECCCCCEEEEEEEEC
SDDDDPLVGSWLVHKDTPGITIIEDWDHLGMRATSSHEVRFDNVLVPLDHAVSVSPWSAP
CCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEECCEEEECCCCEECCCCCCC
QSELDGSGLLWMAVLLSSVYDGIAQSARDWLVHWLEQRTPSNLGASLSTLPRFQETVGQI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
DTLLFANRTLLHSAAHGHTPAQHAGQIKYLVTGNAIRAVELAIEASGNPGLSRSNPLQRH
HHHHHHHHHHHHHHHCCCCCHHHCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCHHHHH
YRNVLCGRVHTPQNDAVLVNVGKAAFAARSKDQ
HHHHHHCCCCCCCCCEEEEEECHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]