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The map label for this gene is atoS [H]

Identifier: 66046689

GI number: 66046689

Start: 4123865

End: 4125079

Strand: Reverse

Name: atoS [H]

Synonym: Psyr_3460

Alternate gene names: 66046689

Gene position: 4125079-4123865 (Counterclockwise)

Preceding gene: 66046690

Following gene: 66046688

Centisome position: 67.69

GC content: 61.89

Gene sequence:

>1215_bases
ATGTCCCAGGCCGCCCAACTGACTTCCGCCCTATCTGTTCAGGCTCCGTACTCCCCGGAGCTGGAAAGTCGTCAGGGGCT
TGAGCACGCATTCTCGCTGTTCAATCAAATGTCGGCACAATTGACCGATTCCTACGGGGTGCTTGAAGCGCGCGTCACCG
AACTCAAGGGCGAACTGGCACATGCCGGCGCCCAGCGTCTTCAGGAGCTGGCGGAAAAAGAACGCCTGGCCAACCGCCTG
CAGAATCTGCTTGATCTGCTGCCCGGCGGGGTGATCGTCATTGATGGCATGGGCGTCGTGCGCGAGGCCAACCCCGCTGC
TATCGATCTGCTCGGGCAGCCGCTGCTGGGCATGCTCTGGCGTCATGTGATCAGCCGCTGCTTTGCACCCCGAGAGGACG
ACGGCCACGAAGTCTCCCTCAAGGACGGTCGCAGGCTCTCGATTGCCACACGCTCGCTGGATGCCGAGCCGGGTCAGTTG
GTATTGCTCAATGACCTGACCGAAACCCGTCATCTTCAGGAACAGCTGGCCCGTCACGAGCGCCTGTCTTCACTGGGGCG
TATGGTCGCCTCTCTGGCGCATCAGATTCGTACGCCGTTGTCCGCTGCCATGATCTACGCCAGCCATTTGACCGAGCAGG
AACTGCCGGTGGAAACCCAGCAGCGTTTCGCCGCGCGGCTCAAGGATCGTTTGCATGAGCTGGAGCATCAGGTTCGCGAC
ATGCTGGTGTTCGCCCGCGGCGAATTGCCGCTGACGGATCGCCTGACGCCCGGTGCTCTGTTTCAGGCGCTGCAAAATGC
GGCTGCGACGCATGTTCAGGGCGTTTCGGTGCGCTGGCAGTGCGACAGCATCGATGGCGAGCTGCTGTGCAATCGCGACA
CACTGGTCGGCGCACTGCTCAATCTGATTGAAAACGCCGTCCAGGCCAGCGCTGGCCGGACGCTGCTGAAAATTCACGCC
TACAGTCGCGGCAACGAACTGCGAATCTGCTTCAGCGATAACGGCAGCGGCATTGACAAGGCCGCGCTGGCGCGCATCGG
TGAGCCGTTCTTTACGACCAAGACCACCGGCACAGGGCTTGGTCTGGCCGTGGTGACGGCGGTGTCGCGTGCGCATCAGG
GGCGCGTGGATTATTTGTCGCGGGTCGGCCGTGGTACCTGCGCCATTGTCAGTCTGCCGTTGATCCCGGCTTCCAGTCCG
ACAGGTAATAACTGA

Upstream 100 bases:

>100_bases
CCAAGCCCCTGATTTTTCAGGGGTTTTTTTTAGGCACGGGGATTGCTAAGTCTCTCTTAACACACCGTTTACTGACGGTT
CGCCACGAGAGAGATGAATC

Downstream 100 bases:

>100_bases
TGCCGATCAATGTGCTGCTGGTCGAGGATGACCGTTCGCTCCGGGAAGCGCTTGGGGAAACCCTCGAGCTGGCCGGTTAT
GACTATAAGGCGGTCGGTTC

Product: flagellar sensor histidine kinase FleS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSQAAQLTSALSVQAPYSPELESRQGLEHAFSLFNQMSAQLTDSYGVLEARVTELKGELAHAGAQRLQELAEKERLANRL
QNLLDLLPGGVIVIDGMGVVREANPAAIDLLGQPLLGMLWRHVISRCFAPREDDGHEVSLKDGRRLSIATRSLDAEPGQL
VLLNDLTETRHLQEQLARHERLSSLGRMVASLAHQIRTPLSAAMIYASHLTEQELPVETQQRFAARLKDRLHELEHQVRD
MLVFARGELPLTDRLTPGALFQALQNAAATHVQGVSVRWQCDSIDGELLCNRDTLVGALLNLIENAVQASAGRTLLKIHA
YSRGNELRICFSDNGSGIDKAALARIGEPFFTTKTTGTGLGLAVVTAVSRAHQGRVDYLSRVGRGTCAIVSLPLIPASSP
TGNN

Sequences:

>Translated_404_residues
MSQAAQLTSALSVQAPYSPELESRQGLEHAFSLFNQMSAQLTDSYGVLEARVTELKGELAHAGAQRLQELAEKERLANRL
QNLLDLLPGGVIVIDGMGVVREANPAAIDLLGQPLLGMLWRHVISRCFAPREDDGHEVSLKDGRRLSIATRSLDAEPGQL
VLLNDLTETRHLQEQLARHERLSSLGRMVASLAHQIRTPLSAAMIYASHLTEQELPVETQQRFAARLKDRLHELEHQVRD
MLVFARGELPLTDRLTPGALFQALQNAAATHVQGVSVRWQCDSIDGELLCNRDTLVGALLNLIENAVQASAGRTLLKIHA
YSRGNELRICFSDNGSGIDKAALARIGEPFFTTKTTGTGLGLAVVTAVSRAHQGRVDYLSRVGRGTCAIVSLPLIPASSP
TGNN
>Mature_403_residues
SQAAQLTSALSVQAPYSPELESRQGLEHAFSLFNQMSAQLTDSYGVLEARVTELKGELAHAGAQRLQELAEKERLANRLQ
NLLDLLPGGVIVIDGMGVVREANPAAIDLLGQPLLGMLWRHVISRCFAPREDDGHEVSLKDGRRLSIATRSLDAEPGQLV
LLNDLTETRHLQEQLARHERLSSLGRMVASLAHQIRTPLSAAMIYASHLTEQELPVETQQRFAARLKDRLHELEHQVRDM
LVFARGELPLTDRLTPGALFQALQNAAATHVQGVSVRWQCDSIDGELLCNRDTLVGALLNLIENAVQASAGRTLLKIHAY
SRGNELRICFSDNGSGIDKAALARIGEPFFTTKTTGTGLGLAVVTAVSRAHQGRVDYLSRVGRGTCAIVSLPLIPASSPT
GNN

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=30.5483028720627, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=31.9327731092437, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=24.6913580246914, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43952; Mature: 43821

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAAQLTSALSVQAPYSPELESRQGLEHAFSLFNQMSAQLTDSYGVLEARVTELKGELA
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
HAGAQRLQELAEKERLANRLQNLLDLLPGGVIVIDGMGVVREANPAAIDLLGQPLLGMLW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCHHHHHHCCHHHHHHH
RHVISRCFAPREDDGHEVSLKDGRRLSIATRSLDAEPGQLVLLNDLTETRHLQEQLARHE
HHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHH
RLSSLGRMVASLAHQIRTPLSAAMIYASHLTEQELPVETQQRFAARLKDRLHELEHQVRD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLVFARGELPLTDRLTPGALFQALQNAAATHVQGVSVRWQCDSIDGELLCNRDTLVGALL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHH
NLIENAVQASAGRTLLKIHAYSRGNELRICFSDNGSGIDKAALARIGEPFFTTKTTGTGL
HHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEECCCCCCH
GLAVVTAVSRAHQGRVDYLSRVGRGTCAIVSLPLIPASSPTGNN
HHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SQAAQLTSALSVQAPYSPELESRQGLEHAFSLFNQMSAQLTDSYGVLEARVTELKGELA
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
HAGAQRLQELAEKERLANRLQNLLDLLPGGVIVIDGMGVVREANPAAIDLLGQPLLGMLW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCHHHHHHCCHHHHHHH
RHVISRCFAPREDDGHEVSLKDGRRLSIATRSLDAEPGQLVLLNDLTETRHLQEQLARHE
HHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHH
RLSSLGRMVASLAHQIRTPLSAAMIYASHLTEQELPVETQQRFAARLKDRLHELEHQVRD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLVFARGELPLTDRLTPGALFQALQNAAATHVQGVSVRWQCDSIDGELLCNRDTLVGALL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHH
NLIENAVQASAGRTLLKIHAYSRGNELRICFSDNGSGIDKAALARIGEPFFTTKTTGTGL
HHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEECCCCCCH
GLAVVTAVSRAHQGRVDYLSRVGRGTCAIVSLPLIPASSPTGNN
HHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]