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The map label for this gene is anr [H]

Identifier: 66046654

GI number: 66046654

Start: 4089470

End: 4090204

Strand: Direct

Name: anr [H]

Synonym: Psyr_3425

Alternate gene names: 66046654

Gene position: 4089470-4090204 (Clockwise)

Preceding gene: 66046652

Following gene: 66046655

Centisome position: 67.11

GC content: 57.01

Gene sequence:

>735_bases
ATGTCCGAGCCAGTCAAGTTGCGCGCTCAAACCCAGGCTCACTGCAAGGATTGCAGTCTCGCGCCGTTGTGCCTGCCCCT
TTCGTTAAATACCGAAGACATGGACTGCCTTGACCAGATCGTCAAACGCGGCCGGCCACTGAAGAAAGGCGAGTTTCTGT
TTCGCCAGGGTGACACCTTCGAGTCGGTCTACGCGGTGCGTTCCGGGGCGTTGAAAACCTTCAATATCAGTGACAGCGGT
GAAGAACAACTCACCGGCTTTCACCTGCCCAGCGAACTGGTAGGCATGTCCGGTATGGACGCCGAGGCTTACCCGGTCTC
GGCGCAGGCACTGGAAACCACATCGGTCTGCGAAATCCCTTTCGAGCGCCTGGACGAGCTGTCCGTAAGACTGCCGCAAC
TGCGTCGGCAGTTGATGCGCGTCATGAGCCGTGAGATCCGTGACGATCAGCAAATGATGCTGCTGCTGTCGAAAAAGACC
GCCGATGAGCGTATCGCCACGTTTCTGATCAATCTGTCTGCACGCTTTCGCGCCAGAGGCTTTTCGGCCAATCAGTTCCG
CCTGAGCATGTCGCGCAATGAAATCGGTAATCACCTGGGTCTGGCAGTCGAGACGGTGTCCCGTGTATTTACCCGATTCC
AGCAAAATCAGCTGATTTCTGCCGAGGGCAAAGAGATACACATCCTCGACCCCATCGAGCTGTGTGCGCTGGCTGGCGGG
TCGATGCAAAGCTGA

Upstream 100 bases:

>100_bases
CGCAACCTTGACGACGCCGACAGGTTTGCAGGCTGGCCCCGACAAGCCTGGGTGAGTTACCCTTACGGCTTATGTGTGAT
TTCCCACAAGGAATTAAGTG

Downstream 100 bases:

>100_bases
AACGTGCGATCTTTGGCGGGTCGGCTTAAACTGTCGGCCAAAACTGCCATGGAACCCCCTGATGACTTTCGATCAATCGA
ACTTCAAATCCCTCATCCGC

Product: cyclic nucleotide-binding: regulatory protein, Crp

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSEPVKLRAQTQAHCKDCSLAPLCLPLSLNTEDMDCLDQIVKRGRPLKKGEFLFRQGDTFESVYAVRSGALKTFNISDSG
EEQLTGFHLPSELVGMSGMDAEAYPVSAQALETTSVCEIPFERLDELSVRLPQLRRQLMRVMSREIRDDQQMMLLLSKKT
ADERIATFLINLSARFRARGFSANQFRLSMSRNEIGNHLGLAVETVSRVFTRFQQNQLISAEGKEIHILDPIELCALAGG
SMQS

Sequences:

>Translated_244_residues
MSEPVKLRAQTQAHCKDCSLAPLCLPLSLNTEDMDCLDQIVKRGRPLKKGEFLFRQGDTFESVYAVRSGALKTFNISDSG
EEQLTGFHLPSELVGMSGMDAEAYPVSAQALETTSVCEIPFERLDELSVRLPQLRRQLMRVMSREIRDDQQMMLLLSKKT
ADERIATFLINLSARFRARGFSANQFRLSMSRNEIGNHLGLAVETVSRVFTRFQQNQLISAEGKEIHILDPIELCALAGG
SMQS
>Mature_243_residues
SEPVKLRAQTQAHCKDCSLAPLCLPLSLNTEDMDCLDQIVKRGRPLKKGEFLFRQGDTFESVYAVRSGALKTFNISDSGE
EQLTGFHLPSELVGMSGMDAEAYPVSAQALETTSVCEIPFERLDELSVRLPQLRRQLMRVMSREIRDDQQMMLLLSKKTA
DERIATFLINLSARFRARGFSANQFRLSMSRNEIGNHLGLAVETVSRVFTRFQQNQLISAEGKEIHILDPIELCALAGGS
MQS

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=52.6548672566372, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27345; Mature: 27214

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPVKLRAQTQAHCKDCSLAPLCLPLSLNTEDMDCLDQIVKRGRPLKKGEFLFRQGDTF
CCCCCEECCCHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCH
ESVYAVRSGALKTFNISDSGEEQLTGFHLPSELVGMSGMDAEAYPVSAQALETTSVCEIP
HHHHHHHHCCEEEEECCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCC
FERLDELSVRLPQLRRQLMRVMSREIRDDQQMMLLLSKKTADERIATFLINLSARFRARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
FSANQFRLSMSRNEIGNHLGLAVETVSRVFTRFQQNQLISAEGKEIHILDPIELCALAGG
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECHHHHHHHCCC
SMQS
CCCC
>Mature Secondary Structure 
SEPVKLRAQTQAHCKDCSLAPLCLPLSLNTEDMDCLDQIVKRGRPLKKGEFLFRQGDTF
CCCCEECCCHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCH
ESVYAVRSGALKTFNISDSGEEQLTGFHLPSELVGMSGMDAEAYPVSAQALETTSVCEIP
HHHHHHHHCCEEEEECCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCC
FERLDELSVRLPQLRRQLMRVMSREIRDDQQMMLLLSKKTADERIATFLINLSARFRARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
FSANQFRLSMSRNEIGNHLGLAVETVSRVFTRFQQNQLISAEGKEIHILDPIELCALAGG
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEECHHHHHHHCCC
SMQS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]